Bupivacaine
- Generic Name
- Bupivacaine
- Brand Names
- Exparel, Kenalog, Marbeta, Marcaine, Marcaine With Epinephrine, Marvona Suik, P-Care M, P-Care MG, P-care, Posimir, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Sensorcaine, Sensorcaine With Epinephrine, Vivacaine, Xaracoll, Exparel liposomal
- Drug Type
- Small Molecule
- Chemical Formula
- C18H28N2O
- CAS Number
- 38396-39-3
- Unique Ingredient Identifier
- Y8335394RO
- Background
Bupivacaine is a widely used local anesthetic agent.
- Indication
As an implant, bupivacaine is indicated in adults for placement into the surgical site to produce postsurgical analgesia for up to 24 hours following open inguinal hernia repair.
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- Associated Conditions
- Acute Gouty Arthritis, Adrenocortical Insufficiency, Alopecia Areata (AA), Ankylosing Spondylitis (AS), Berylliosis, Bullous dermatitis herpetiformis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatomyositis (DM), Discoid Lupus Erythematosus (DLE), Edema of the cerebrum, Epicondylitis, Hemolytic Anemia, Hypercalcemia caused by Cancer, Keloids Scars, Leukemias, Mycosis Fungoides (MF), Necrobiosis lipoidica diabeticorum, Ocular Inflammation, Ophthalmia, Sympathetic, Osteoarthritis (OA), Pain, Labor, Polymyositis, Postoperative pain, Psoriatic Arthritis, Psoriatic plaque, Pure Red Cell Aplasia, Regional Enteritis, Rheumatoid Arthritis, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Acute Bursitis, Acute Idiopathic Nephrotic Syndrome, Acute Lupus Erythematosus, Acute Multiple sclerosis, Acute Rheumatic heart disease, unspecified, Acute nonspecific tenosynovitis, Cystic tumors of aponeurosis, Cystic tumors of tendon, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Inflammatory lesions of granuloma annulare, Inflammatory lesions of lichen planus, Inflammatory lesions of lichen simplex, Non-suppurative Thyroiditis, Permphigus, Severe Allergic Reactions
- Associated Therapies
- General Anesthesia, Local Anaesthesia therapy, Regional nerve block therapy
Exparel vs. ACB With Bupivacaine for ACL Reconstruction
- First Posted Date
- 2024-02-23
- Last Posted Date
- 2024-02-23
- Lead Sponsor
- Children's Hospital of Orange County
- Target Recruit Count
- 96
- Registration Number
- NCT06274008
- Locations
- 🇺🇸
CHOC Children's Hospital, Orange, California, United States
Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoing Cardiac Surgery
- First Posted Date
- 2024-02-21
- Last Posted Date
- 2024-10-24
- Lead Sponsor
- Pacira Pharmaceuticals, Inc
- Target Recruit Count
- 48
- Registration Number
- NCT06271265
- Locations
- 🇺🇸
Duke University Health System, Durham, North Carolina, United States
🇺🇸University of Oklahoma (OU) - Medical Center - The Children's Hospital, Oklahoma City, Oklahoma, United States
🇺🇸The University of Texas Health Science Center at Houston (UTHSC-H) - McGovern Medical School, Houston, Texas, United States
Dexmedetomidine in Obturator Nerve Block as an Analgesic in Transurethral Surgeries
- Conditions
- Interventions
- First Posted Date
- 2024-01-29
- Last Posted Date
- 2024-08-12
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 56
- Registration Number
- NCT06229054
- Locations
- 🇪🇬
Faculty of Medicine-Cairo Univeristy, Cairo, Egypt
Bilateral Rhomboid Intercostal Block for Perioperative Analgesia in Patients Undergoing Bilateral Reduction Mammoplasty
- Conditions
- Interventions
- First Posted Date
- 2024-01-26
- Last Posted Date
- 2024-07-24
- Lead Sponsor
- Zagazig University
- Target Recruit Count
- 72
- Registration Number
- NCT06225895
- Locations
- 🇪🇬
Shereen E Abd Ellatif, Zagazig, Alsharqia, Egypt
🇪🇬Faculty of medicine, zagazig university, Zagazig, Alsharqia, Egypt
Supraclavicular Bupivacaine Vs. Supraclavicular Liposomal Bupivacaine for Distal Radius Fracture Repair
- Conditions
- Interventions
- First Posted Date
- 2023-12-21
- Last Posted Date
- 2024-06-17
- Lead Sponsor
- University of North Carolina, Chapel Hill
- Target Recruit Count
- 100
- Registration Number
- NCT06179004
- Locations
- 🇺🇸
UNC Chapel Hill, Chapel Hill, North Carolina, United States
Effect of Prilocaine vs Bupivacaine on Hemodynamics in Spinal Anesthesia for Geriatric Patients
- First Posted Date
- 2023-12-11
- Last Posted Date
- 2024-07-23
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 112
- Registration Number
- NCT06165679
- Locations
- 🇪🇬
Kasr Alaini hospital, Cairo, Egypt
ED90 of Bupivacaine After Lidocaine Test Dose With DPE and EPL
- First Posted Date
- 2023-11-27
- Last Posted Date
- 2023-11-27
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT06146842
Effect of Prilocaine on Motor Block During Caesarean Section
- Conditions
- Interventions
- First Posted Date
- 2023-11-18
- Last Posted Date
- 2024-02-28
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 40
- Registration Number
- NCT06133881
- Locations
- 🇪🇬
Faculty of Medicine Cairo University, Cairo, Egypt
Intraperitoneal Bupivacaine for Pelvic Organ Prolapse
- First Posted Date
- 2023-11-07
- Last Posted Date
- 2024-11-07
- Lead Sponsor
- Indiana University
- Target Recruit Count
- 91
- Registration Number
- NCT06120530
- Locations
- 🇺🇸
IU north, Carmel, Indiana, United States
A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE.
- First Posted Date
- 2023-10-31
- Last Posted Date
- 2023-10-31
- Lead Sponsor
- Heron Therapeutics
- Target Recruit Count
- 30
- Registration Number
- NCT06109415
- Locations
- 🇺🇸
First Surgical Hospital, Bellaire, Texas, United States
🇺🇸Legent Orthopedic Hospital, Carrollton, Texas, United States
🇺🇸JBR Clinical Research, Salt Lake City, Utah, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.