Bupivacaine
- Generic Name
- Bupivacaine
- Brand Names
- Exparel, Kenalog, Marbeta, Marcaine, Marcaine With Epinephrine, Marvona Suik, P-Care M, P-Care MG, P-care, Posimir, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Sensorcaine, Sensorcaine With Epinephrine, Vivacaine, Xaracoll, Exparel liposomal
- Drug Type
- Small Molecule
- Chemical Formula
- C18H28N2O
- CAS Number
- 38396-39-3
- Unique Ingredient Identifier
- Y8335394RO
- Background
Bupivacaine is a widely used local anesthetic agent.
- Indication
As an implant, bupivacaine is indicated in adults for placement into the surgical site to produce postsurgical analgesia for up to 24 hours following open inguinal hernia repair.
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- Associated Conditions
- Acute Gouty Arthritis, Adrenocortical Insufficiency, Alopecia Areata (AA), Ankylosing Spondylitis (AS), Berylliosis, Bullous dermatitis herpetiformis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatomyositis (DM), Discoid Lupus Erythematosus (DLE), Edema of the cerebrum, Epicondylitis, Hemolytic Anemia, Hypercalcemia caused by Cancer, Keloids Scars, Leukemias, Mycosis Fungoides (MF), Necrobiosis lipoidica diabeticorum, Ocular Inflammation, Ophthalmia, Sympathetic, Osteoarthritis (OA), Pain, Labor, Polymyositis, Postoperative pain, Psoriatic Arthritis, Psoriatic plaque, Pure Red Cell Aplasia, Regional Enteritis, Rheumatoid Arthritis, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Acute Bursitis, Acute Idiopathic Nephrotic Syndrome, Acute Lupus Erythematosus, Acute Multiple sclerosis, Acute Rheumatic heart disease, unspecified, Acute nonspecific tenosynovitis, Cystic tumors of aponeurosis, Cystic tumors of tendon, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Inflammatory lesions of granuloma annulare, Inflammatory lesions of lichen planus, Inflammatory lesions of lichen simplex, Non-suppurative Thyroiditis, Permphigus, Severe Allergic Reactions
- Associated Therapies
- General Anesthesia, Local Anaesthesia therapy, Regional nerve block therapy
Dorsal Penile Block for Post-Robotic Prostatectomy Foley Discomfort
- Conditions
- Interventions
- First Posted Date
- 2012-03-28
- Last Posted Date
- 2015-03-05
- Lead Sponsor
- Columbia University
- Registration Number
- NCT01565512
- Locations
- 🇺🇸
New York Presbyterian Hospital/Columbia University, New York, New York, United States
Transversus Abdominis Plane Blocks for Infants and Children for Postoperative Pain Control
- First Posted Date
- 2012-03-21
- Last Posted Date
- 2012-03-21
- Target Recruit Count
- 36
- Registration Number
- NCT01559740
- Locations
- 🇺🇸
Children's Memorial Hospital, Chicago, Illinois, United States
Single Dose Pharmacokinetics and Pharmacodynamics of Bupivacaine Following Transversus Abdominis Plane (TAP) Block in Neonates
- First Posted Date
- 2012-03-20
- Last Posted Date
- 2013-03-21
- Target Recruit Count
- 13
- Registration Number
- NCT01557985
- Locations
- 🇺🇸
Ann & Robert H Lurie Children's Hospital of Chicago, Chicago, Illinois, United States
Superficial Cervical Plexus Block for Shoulder Pain After Lung Surgery
- Conditions
- Interventions
- First Posted Date
- 2012-03-09
- Last Posted Date
- 2017-07-18
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 10
- Registration Number
- NCT01550302
- Locations
- 🇺🇸
University of Washington, Seattle, Washington, United States
Plasma Glucose Levels With Dexamethasone as Adjuvant to Interscalene Block
- Conditions
- Interventions
- First Posted Date
- 2012-02-24
- Last Posted Date
- 2013-05-20
- Lead Sponsor
- Lifespan
- Registration Number
- NCT01538459
- Locations
- 🇺🇸
Newport Hospital, Newport, Rhode Island, United States
Effect of Paracervical Block on Post Operative Pain in Laparoscopic Gynecologic Surgery
- Conditions
- Interventions
- First Posted Date
- 2012-02-16
- Last Posted Date
- 2017-12-20
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Target Recruit Count
- 132
- Registration Number
- NCT01534416
- Locations
- 🇺🇸
Icahn School of Medicine at Mount Sinai, New York, New York, United States
Randomized Control Trial of Intraperitoneal Bupivacaine During Cholecystectomy
- Conditions
- Interventions
- First Posted Date
- 2012-02-08
- Last Posted Date
- 2012-02-08
- Target Recruit Count
- 42
- Registration Number
- NCT01528722
- Locations
- 🇬🇧
University Hospitals Coventry and Warwickshire, Coventry, Warwickshire, United Kingdom
Clinical Trial Examining the Short and Long-term Effect of Myofascial Trigger Points Injection in Low Back Pain Patients
- First Posted Date
- 2012-01-30
- Last Posted Date
- 2013-07-29
- Lead Sponsor
- Dr. Yoram Shir
- Target Recruit Count
- 40
- Registration Number
- NCT01520415
- Locations
- 🇨🇦
Alan Edwards Pain Management Unit - Montreal General Hospital, Montreal, Quebec, Canada
A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S23B504
- Conditions
- Interventions
- First Posted Date
- 2012-01-13
- Last Posted Date
- 2014-04-07
- Lead Sponsor
- Pacira Pharmaceuticals, Inc
- Target Recruit Count
- 33
- Registration Number
- NCT01509807
- Locations
- 🇺🇸
Florida Hospital d/b/a Colon & Rectal Surgery Center, Orlando, Florida, United States
🇺🇸University of Arizona College of Medicine, Tucson, Arizona, United States
🇺🇸University of South Florida, Tampa, Florida, United States
Bupivacaine Pain Pumps to Decrease Mastectomy Post-Operative Pain
- First Posted Date
- 2011-12-16
- Last Posted Date
- 2015-10-14
- Lead Sponsor
- Johns Hopkins University
- Registration Number
- NCT01494259
- Locations
- 🇺🇸
Dept. of Plastic and Reconstructive Surgery, Johns Hopkins, Baltimore, Maryland, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.