Bupivacaine
- Generic Name
- Bupivacaine
- Brand Names
- Exparel, Kenalog, Marbeta, Marcaine, Marcaine With Epinephrine, Marvona Suik, P-Care M, P-Care MG, P-care, Posimir, Readysharp Anesthetics Plus Ketorolac, Readysharp-A, Readysharp-p40, Readysharp-p80, Sensorcaine, Sensorcaine With Epinephrine, Vivacaine, Xaracoll, Exparel liposomal
- Drug Type
- Small Molecule
- Chemical Formula
- C18H28N2O
- CAS Number
- 38396-39-3
- Unique Ingredient Identifier
- Y8335394RO
- Background
Bupivacaine is a widely used local anesthetic agent.
- Indication
As an implant, bupivacaine is indicated in adults for placement into the surgical site to produce postsurgical analgesia for up to 24 hours following open inguinal hernia repair.
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- Associated Conditions
- Acute Gouty Arthritis, Adrenocortical Insufficiency, Alopecia Areata (AA), Ankylosing Spondylitis (AS), Berylliosis, Bullous dermatitis herpetiformis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Dermatomyositis (DM), Discoid Lupus Erythematosus (DLE), Edema of the cerebrum, Epicondylitis, Hemolytic Anemia, Hypercalcemia caused by Cancer, Keloids Scars, Leukemias, Mycosis Fungoides (MF), Necrobiosis lipoidica diabeticorum, Ocular Inflammation, Ophthalmia, Sympathetic, Osteoarthritis (OA), Pain, Labor, Polymyositis, Postoperative pain, Psoriatic Arthritis, Psoriatic plaque, Pure Red Cell Aplasia, Regional Enteritis, Rheumatoid Arthritis, Secondary thrombocytopenia, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Acute Bursitis, Acute Idiopathic Nephrotic Syndrome, Acute Lupus Erythematosus, Acute Multiple sclerosis, Acute Rheumatic heart disease, unspecified, Acute nonspecific tenosynovitis, Cystic tumors of aponeurosis, Cystic tumors of tendon, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Inflammatory lesions of granuloma annulare, Inflammatory lesions of lichen planus, Inflammatory lesions of lichen simplex, Non-suppurative Thyroiditis, Permphigus, Severe Allergic Reactions
- Associated Therapies
- General Anesthesia, Local Anaesthesia therapy, Regional nerve block therapy
Dose-ranging Study for Postoperative Analgesia in Subjects Undergoing Primary Unilateral Inguinal Hernia Repair
- First Posted Date
- 2007-06-13
- Last Posted Date
- 2021-03-02
- Lead Sponsor
- Pacira Pharmaceuticals, Inc
- Target Recruit Count
- 98
- Registration Number
- NCT00485433
- Locations
- 🇺🇸
Saddleback Valley Outpatient Surgery, Laguna Hills, California, United States
🇺🇸Kirby Outpatient Surgical Center, Houston, Texas, United States
🇺🇸Arcadia Methodist Hospital, Arcadia, California, United States
Dose-Ranging Study for Prolonged Postoperative Analgesia in Subject Undergoing Total Knee Arthroplasty
- First Posted Date
- 2007-06-13
- Last Posted Date
- 2022-06-28
- Lead Sponsor
- Pacira Pharmaceuticals, Inc
- Target Recruit Count
- 138
- Registration Number
- NCT00485693
- Locations
- 🇺🇸
West Alabama Research, Inc., Birmingham, Alabama, United States
🇺🇸California Clinical Research, Inc., Davis, California, United States
🇺🇸The Ohio State University Medical Center, Columbus, Ohio, United States
Laparoscopic Ventral Hernia Repair With Elastomeric Pain Pump
- Conditions
- Interventions
- First Posted Date
- 2007-05-11
- Last Posted Date
- 2015-06-08
- Lead Sponsor
- University Hospitals Cleveland Medical Center
- Target Recruit Count
- 100
- Registration Number
- NCT00472134
- Locations
- 🇺🇸
University Hospitals of Cleveland, Cleveland, Ohio, United States
Minimum Local Anesthetic Volume of Bupivacaine in Labour Epidurals
- First Posted Date
- 2007-03-21
- Last Posted Date
- 2007-12-17
- Target Recruit Count
- 50
- Registration Number
- NCT00450099
- Locations
- 🇨🇦
Mount Sinai Hospital, Toronto, Ontario, Canada
A Comparison of Bupivacaine and Ketorolac for Postoperative Analgesia After Iliac Crest Bone Harvesting
- Conditions
- Interventions
- First Posted Date
- 2006-11-30
- Last Posted Date
- 2013-08-20
- Lead Sponsor
- The Hospital for Sick Children
- Target Recruit Count
- 54
- Registration Number
- NCT00405262
- Locations
- 🇨🇦
The Hospital for Sick Children, Toronto, Ontario, Canada
Ropivacaine Versus Bupivacaine for Spinal Anaesthesia in Patients Undergoing Unilateral Lower Limb Surgery
- Conditions
- First Posted Date
- 2006-07-31
- Last Posted Date
- 2009-03-26
- Lead Sponsor
- AstraZeneca
- Target Recruit Count
- 220
- Registration Number
- NCT00358280
- Locations
- 🇨🇳
Research Site, Xi'an, China
Efficacy Study of Continuous Intraarticular Infusion in Patients Undergoing Arthroscopic Knee and Shoulder Operations
- Conditions
- First Posted Date
- 2006-04-14
- Last Posted Date
- 2009-07-13
- Lead Sponsor
- Children's Hospital of Philadelphia
- Target Recruit Count
- 16
- Registration Number
- NCT00314457
- Locations
- 🇺🇸
The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
A Phase I Safety and Immunogenicity Trial of the Facilitated HIV-1 Gag-Pol DNA Vaccine (APL-400-047, Apollon, Inc.) Given Intramuscularly by Needle and Syringe or Biojector 2000 Needle-Free Jet Injection System in HIV-1 Uninfected Adult Volunteers
- Conditions
- First Posted Date
- 2001-08-31
- Last Posted Date
- 2008-09-29
- Target Recruit Count
- 40
- Registration Number
- NCT00001088
- Locations
- 🇺🇸
Vanderbilt Univ Hosp, Nashville, Tennessee, United States
🇺🇸Univ of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸Univ of Rochester Med Ctr, Rochester, New York, United States
Drug Development Updates
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