Anastrozole
- Generic Name
- Anastrozole
- Brand Names
- Arimidex
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19N5
- CAS Number
- 120511-73-1
- Unique Ingredient Identifier
- 2Z07MYW1AZ
- Background
Anastrozole is a non-steroidal aromatase inhibitor (AI), similar to letrozole, used to decrease circulating estrogen levels in the treatment of postmenopausal women with estrogen-responsive breast cancer. Anastrozole is also related to exemestane, a steroidal AI, but its non-steroidal nature provides stark advantages including a lack of steroid-associated ad...
- Indication
Anastrozole is indicated as adjunct therapy in the treatment of hormone receptor-positive early breast cancer in postmenopausal women, and as a first-line treatment for hormone receptor-positive (or hormone receptor-unknown) locally advanced or metastatic breast cancer in postmenopausal women. It may also be used in the treatment of advanced breast cancer in...
- Associated Conditions
- Advanced Breast Cancer, Invasive Early Breast Cancer, Locally Advanced Breast Cancer (LABC), Metastatic Breast Cancer, Stage I Breast Cancer
- Associated Therapies
- -
Combination Chemotherapy Compared With Observation After Surgery in Treating Women With Relapsed Nonmetastatic Breast Cancer
- Conditions
- First Posted Date
- 2003-02-06
- Last Posted Date
- 2014-12-16
- Lead Sponsor
- UNICANCER
- Registration Number
- NCT00053911
- Locations
- 🇫🇷
Clinique Claude Bernard, Albi, France
🇫🇷Institut Bergonie, Bordeaux, France
🇫🇷Centre Paul Papin, Angers, France
Anastrozole and ZD 1839 in Treating Postmenopausal Women With Metastatic Breast Cancer
- Conditions
- Locations
- 🇺🇸
Cancer Therapy and Research Center, San Antonio, Texas, United States
Primary Chemotherapy With Docetaxel-Capecitabine and Doxorubicin-Cyclophosphamide in Breast Cancer
- First Posted Date
- 2000-06-14
- Last Posted Date
- 2013-03-19
- Lead Sponsor
- National Cancer Institute (NCI)
- Target Recruit Count
- 30
- Registration Number
- NCT00005908
- Locations
- 🇺🇸
National Naval Medical Center, Bethesda, Maryland, United States
Drug Development Updates
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