MedPath

Maridebart Cafraglutide

Generic Name
Maridebart Cafraglutide

A Study to Evaluate AMG 133 Administered Subcutaneously in Participants With Overweight or Obesity

Phase 1
Completed
Conditions
Obesity
Overweight
Interventions
First Posted Date
2025-05-16
Last Posted Date
2025-05-16
Lead Sponsor
Amgen
Target Recruit Count
120
Registration Number
NCT06976372
Locations
πŸ‡ΊπŸ‡Έ

CenExel, Anaheim, California, United States

πŸ‡ΊπŸ‡Έ

CenExel Collaborative Neuroscience Research, LLC Los Alamitos, Los Alamitos, California, United States

πŸ‡ΊπŸ‡Έ

Fortrea Clinical Research Unit - Dallas, Dallas, Texas, United States

Evaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight

Phase 3
Recruiting
Conditions
Obesity
Interventions
First Posted Date
2025-03-05
Last Posted Date
2025-05-14
Lead Sponsor
Amgen
Target Recruit Count
3501
Registration Number
NCT06858839
Locations
πŸ‡ΊπŸ‡Έ

Indago Research and Health Center, Hialeah, Florida, United States

πŸ‡ΊπŸ‡Έ

Yale School of Medicine, New Haven, Connecticut, United States

πŸ‡ΊπŸ‡Έ

Pinnacle Research Group LLC, Anniston, Alabama, United States

and more 99 locations

Efficacy and Safety of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight

Phase 3
Recruiting
Conditions
Type 2 Diabetes Mellitus (T2DM), Obesity, Overweight
Interventions
First Posted Date
2025-03-05
Last Posted Date
2025-05-14
Lead Sponsor
Amgen
Target Recruit Count
999
Registration Number
NCT06858878
Locations
πŸ‡ΊπŸ‡Έ

Alliance for Multispecialty Research Mobile, Mobile, Alabama, United States

πŸ‡ΊπŸ‡Έ

Gilbert Center for Family Medicine, Gilbert, Arizona, United States

πŸ‡ΊπŸ‡Έ

Desert Clinical Research, Mesa, Arizona, United States

and more 69 locations

A Study of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus (T2DM)

Phase 2
Active, not recruiting
Conditions
Type 2 Diabetes Mellitus (T2DM)
Interventions
First Posted Date
2024-10-28
Last Posted Date
2025-05-16
Lead Sponsor
Amgen
Target Recruit Count
409
Registration Number
NCT06660173
Locations
πŸ‡΅πŸ‡±

Centrum Badan Klinicznych Piotr Napora lekarze spolka partnerska, Wroclaw, Poland

πŸ‡΅πŸ‡±

Futuremeds spolka z ograniczona odpowiedzialnoscia, Wroclaw, Poland

πŸ‡΅πŸ‡·

Latin Clinical Trial Center, San Juan, Puerto Rico

and more 92 locations

A Study to Evaluate AMG 133 in Chinese Participants With Obesity or Overweight

Phase 1
Active, not recruiting
Conditions
Obesity
Interventions
First Posted Date
2024-04-08
Last Posted Date
2024-08-02
Lead Sponsor
Amgen
Target Recruit Count
20
Registration Number
NCT06352892
Locations
πŸ‡­πŸ‡°

Queen Mary Hospital, Hong Kong, Hong Kong

Dose-ranging Study to Evaluate the Efficacy, Safety, and Tolerability of AMG 133 in Adult Subjects With Overweight or Obesity, With or Without Type 2 Diabetes Mellitus

Phase 2
Active, not recruiting
Conditions
Type 2 Diabetes Mellitus
Overweight
Obesity
Interventions
First Posted Date
2023-01-03
Last Posted Date
2025-02-20
Lead Sponsor
Amgen
Target Recruit Count
592
Registration Number
NCT05669599
Locations
πŸ‡ΊπŸ‡Έ

Progressive Medical Research, Port Orange, Florida, United States

πŸ‡ΊπŸ‡Έ

Diablo Clinical Research, Walnut Creek, California, United States

πŸ‡ΊπŸ‡Έ

Research Innovations LLC dba Internal Medicine Care Inc, Beavercreek, Ohio, United States

and more 75 locations

Study of AMG 133 Administered Subcutaneously in Healthy Japanese and Caucasian Participants

Phase 1
Completed
Conditions
Healthy Participants
Interventions
First Posted Date
2021-09-24
Last Posted Date
2025-02-25
Lead Sponsor
Amgen
Target Recruit Count
34
Registration Number
NCT05056246
Locations
πŸ‡ΊπŸ‡Έ

WCCT Global LLC, Cypress, California, United States

Single and Multiple Ascending Dose Study of AMG 133 in Participants With Obesity

Phase 1
Completed
Conditions
Obesity
Interventions
First Posted Date
2020-07-21
Last Posted Date
2024-08-02
Lead Sponsor
Amgen
Target Recruit Count
110
Registration Number
NCT04478708
Locations
πŸ‡ΊπŸ‡Έ

Anaheim Clinical Trials, Anaheim, California, United States

πŸ‡ΊπŸ‡Έ

Orange County Research Center, Tustin, California, United States

πŸ‡ΊπŸ‡Έ

Clinical Pharmacology of Miami, LLC, Miami, Florida, United States

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