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Citric acid

Generic Name
Citric acid
Brand Names
Alka-seltzer, Alka-seltzer Fruit Chews, Alka-seltzer Heartburn Relief, As 3, Citrasate, Clenpiq, Cpda-1 Blood Collection System, Cytra-K, EnLyte, Hemosate Ultra, Leukotrap, Oracit, Phexxi, Pico-salax, Picoflo, Purg-odan, Renacidin
Drug Type
Small Molecule
Chemical Formula
C6H8O7
CAS Number
77-92-9
Unique Ingredient Identifier
XF417D3PSL

Overview

A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020. It is also used in combination with magnesium oxide to form magnesium citrate, an osmotic laxative.

Background

A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability. Citric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020. It is also used in combination with magnesium oxide to form magnesium citrate, an osmotic laxative.

Indication

No indication information available.

Associated Conditions

  • Acidosis
  • Catheter site calcification caused by appetite
  • Catheter site calcification caused by struvite
  • Gout
  • Headache
  • Heartburn
  • Kidney Stones
  • Metabolic Acidosis

FDA Approved Products

CLENPIQ
Manufacturer:Ferring Pharmaceuticals Inc.
Route:ORAL
Strength:12 g in 160 mL
Approved: 2019/10/31
NDC:55566-6700
Sodium Citrate and Citric Acid
Manufacturer:MAJOR® PHARMACEUTICALS
Route:ORAL
Strength:334 mg in 5 mL
Approved: 2023/08/01
NDC:0904-7316
imuflex wb-sp blood bag system with integral whole blood leukocyte reduction filter (saving platelets) with diversion blood sampling arm
Manufacturer:Terumo Corporation
Route:INTRAVENOUS
Strength:209 mg in 70 mL
Approved: 2021/12/10
NDC:53877-010
Sodium Citrate and Citric Acid
Manufacturer:Pharmaceutical Associates, Inc.
Route:ORAL
Strength:334 mg in 5 mL
Approved: 2022/12/15
NDC:0121-1190
CPDA-1
Manufacturer:Fenwal, Inc.
Route:INTRAVENOUS
Strength:209 mg in 70 mL
Approved: 2014/08/27
NDC:0942-6326

Singapore Approved Products

Ural Effervescent Granules
Manufacturer:Aspen Pharma Pty Ltd
Form:GRANULE, EFFERVESCENT
Strength:0.72g
Online:Yes
Approved: 2013/06/26
Approval:SIN14374P
PICO-SWIFT POWDER FOR ORAL SOLUTION
Manufacturer:IND-SWIFT LIMITED
Form:POWDER, FOR SOLUTION
Strength:12000 mg
Online:Yes
Approved: 2025/01/16
Approval:SIN17163P

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