Olaratumab

Generic Name
Olaratumab
Brand Names
Lartruvo
Drug Type
Biotech
Chemical Formula
-
CAS Number
1024603-93-7
Unique Ingredient Identifier
TT6HN20MVF
Background

Olaratumab (IMC-3G3) is a fully human IgG1 monoclonal antibody with antitumor activity that selectively binds the external domain of human platelet-derived growth factor receptor (PDGFR)-α with high affinity and blocks ligand binding. It is composed of two heavy chain molecule fragments and 2 light chain fragments. Studies show that the treatment of olaratum...

Indication

用于治疗软组织肉瘤。

Associated Conditions
Soft Tissue Sarcoma
Associated Therapies
-

A Study of Olaratumab and Doxorubicin in Participants With Advanced Soft Tissue Sarcoma

Phase 1
Completed
Conditions
Interventions
First Posted Date
2014-12-25
Last Posted Date
2019-11-21
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
49
Registration Number
NCT02326025
Locations
🇺🇸

UCLA Medical Center, Los Angeles, California, United States

🇺🇸

Northwestern University, Chicago, Illinois, United States

🇺🇸

Washington University Medical Center, Saint Louis, Missouri, United States

and more 3 locations
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