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Aminolevulinic Acid

Generic Name: Aminolevulinic Acid

Brand Names: Ameluz, Gliolan, Levulan

Drug Type: Small Molecule

Chemical Formula: C_₅H_₉NO_₃

CAS Number: 106-60-5

Unique Ingredient Identifier: 88755TAZ87

Overview

A compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. It is used as a photochemotherapy for actinic keratosis. [PubChem]

Background

A compound produced from succinyl-CoA and glycine as an intermediate in heme synthesis. It is used as a photochemotherapy for actinic keratosis. [PubChem]

Indication

用于皮肤癌及鲍温病、牛皮癣，男性尿道尖锐湿疣等皮肤病。可治疗消化道肿瘤、口腔癌。可诊断和治疗膀胱癌、尿路上皮肿瘤。能阻止血管成形术后在狭窄。

Associated Conditions

Actinic Cheilitis
Actinic Keratoses of the face
Actinic Keratoses of the scalp
Actinic Keratosis (AK) of the Upper Extremity
Basal Cell Carcinoma (BCC)
Cutaneous Squamous Cell Carcinoma in Situ (CSCCis)
Glioma

Clinical Trials

Efficacy and Safety of Treatment of Actinic Keratoses With Photodynamic Therapy Between MAL Cream and ALA Gel

Phase 4

Posted: 2016/01/06

Sponsor:

Fundación Instituto ...

ID:NCT02647151

5-Aminolevulinic Acid (5-ALA) to Enhance Visualization of Malignant Tumor

Completed

Posted: 2015/12/16

Sponsor:

Constantinos Hadjipa...

ID:NCT02632370

The Use of Microneedles to Expedite Treatment Time in Photodynamic Therapy

Not Applicable

Completed

Posted: 2015/11/03

Sponsor:University of Califo...

ID:NCT02594644

Daylight PDT for Actinic Keratoses: a Multicentre Study Comparing Two Photosensitizers (BF-200 ALA Versus MAL)

Phase 4

Completed

Posted: 2015/06/08

Sponsor:

Joint Authority for ...

ID:NCT02464709

Photodynamic Therapy (PDT) With Levulan and Blue Light for the Treatment of Actinic Cheilitis

Phase 4

Completed

Posted: 2015/04/07

Sponsor:Dartmouth-Hitchcock ...

ID:NCT02409732

FDA Approved Products

No FDA products found for this drug

Singapore Approved Products

No Singapore products found for this drug

Related News

FDA Approves Sun Pharma's Next-Generation LED BLU-U Device for Actinic Keratosis Treatment

7 days ago

The FDA has granted premarket approval for Sun Pharma's next-generation BLU-U Blue Light Photodynamic Therapy Illuminator, featuring LED panels instead of fluorescent tubes for treating actinic keratosis.

Biofrontera's Ameluz Secures Patent Extension to 2043, Targets $5.7B Acne Market

17 days ago

Biofrontera Inc. has secured FDA approval for a reformulated Ameluz nanoemulsion gel, extending patent protection until 2043 and allowing up to three tubes per treatment, potentially increasing revenue through larger average sales.

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Biofrontera's Ameluz-PDT Shows Promise in Phase 3 Trial for Superficial Basal Cell Carcinoma

4 months ago

Biofrontera's Phase 3 trial of Ameluz-PDT for superficial basal cell carcinoma (sBCC) has reached a crucial milestone with all patients completing the 1-year follow-up.

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