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Epinastine

Generic Name
Epinastine
Brand Names
Elestat
Drug Type
Small Molecule
Chemical Formula
C16H15N3
CAS Number
80012-43-7
Unique Ingredient Identifier
Q13WX941EF

Overview

Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to stop itching and provide lasting protection, and 3. prevents the release of proinflammatory chemical mediators from the blood vessel to halt progression of the allergic response.

Background

Epinastine is used for the prevention of itching associated with allergic conjunctivitis. It has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding to both the H1- and H2-receptors to stop itching and provide lasting protection, and 3. prevents the release of proinflammatory chemical mediators from the blood vessel to halt progression of the allergic response.

Indication

For the prevention of itching associated with allergic conjunctivitis.

Associated Conditions

  • Allergic Conjunctivitis (AC)

FDA Approved Products

EPINASTINE HYDROCHLORIDE
Manufacturer:Sun Pharmaceutical Industries, Inc.
Route:OPHTHALMIC
Strength:0.5 mg in 1 mL
Approved: 2018/10/24
NDC:62756-329
Epinastine Hydrochloride
Manufacturer:Breckenridge Pharmaceutical, Inc.
Route:OPHTHALMIC
Strength:0.5 mg in 1 mL
Approved: 2021/11/01
NDC:51991-836
EPINASTINE HYDROCHLORIDE
Manufacturer:Somerset Therapeutics, LLC
Route:OPHTHALMIC
Strength:0.5 mg in 1 mL
Approved: 2023/11/09
NDC:70069-008

Singapore Approved Products

No Singapore products found for this drug

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