Liraglutide
- Generic Name
- Liraglutide
- Brand Names
- Saxenda, Victoza, Xultophy
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 204656-20-2
- Unique Ingredient Identifier
- 839I73S42A
- Background
Victoza contains liraglutide, a synthetic analog of human glucagon-like peptide-1(GLP-1) and acts as a GLP-1 receptor agonist. Liraglutide is 97% similar to native human GLP-1, differing primarily by substituting arginine for lysine at position 34. Liraglutide is made by attaching a C-16 fatty acid (palmitic acid) with a glutamic acid spacer on the remaining...
- Indication
Saxenda, a formulation of liraglutide intended for weight loss, is indicated as an adjunct to diet and exercise for chronic weight management in adult patients who are obese (BMI≥30 kg/m), or who are overweight (BMI≥27 kg/m) and have at least one weight-related comorbidity. It is also indicated for chronic weight management in pediatric patients ≥12 years ol...
- Associated Conditions
- Major Adverse Cardiovascular Events, Type 2 Diabetes Mellitus
- Associated Therapies
- Chronic Weight Management therapy
The Effect of Liraglutide on Endothelial Function in Subjects With Type 2 Diabetes Mellitus
- Conditions
- Interventions
- First Posted Date
- 2008-02-21
- Last Posted Date
- 2017-03-08
- Lead Sponsor
- Novo Nordisk A/S
- Target Recruit Count
- 49
- Registration Number
- NCT00620282
- Locations
- 🇺🇸
Novo Nordisk Investigational Site, Rochester, Minnesota, United States
Effect of Liraglutide or Glimepiride Added to Metformin on Blood Glucose Control in Subjects With Type 2 Diabetes
- Conditions
- Interventions
- First Posted Date
- 2008-02-13
- Last Posted Date
- 2017-03-08
- Lead Sponsor
- Novo Nordisk A/S
- Target Recruit Count
- 929
- Registration Number
- NCT00614120
- Locations
- 🇰🇷
Novo Nordisk Investigational Site, Suwon, Korea, Republic of
Effect of Liraglutide or Exenatide Added to an Ongoing Treatment on Blood Glucose Control in Subjects With Type 2 Diabetes
- Conditions
- Interventions
- First Posted Date
- 2007-08-21
- Last Posted Date
- 2017-03-08
- Lead Sponsor
- Novo Nordisk A/S
- Target Recruit Count
- 467
- Registration Number
- NCT00518882
- Locations
- 🇨🇭
Novo Nordisk Investigational Site, Lugano, Switzerland
The Effect of Liraglutide on Body Weight in Obese Subjects Without Diabetes
- Conditions
- Interventions
- First Posted Date
- 2007-01-15
- Last Posted Date
- 2017-11-01
- Lead Sponsor
- Novo Nordisk A/S
- Target Recruit Count
- 564
- Registration Number
- NCT00422058
- Locations
- 🇬🇧
Novo Nordisk Investigational Site, Norwich, United Kingdom
Effect of Liraglutide in Combination With Sulfonylurea (SU) on Blood Glucose Control in Subjects With Type 2 Diabetes
- Conditions
- Interventions
- First Posted Date
- 2006-11-03
- Last Posted Date
- 2017-03-08
- Lead Sponsor
- Novo Nordisk A/S
- Target Recruit Count
- 264
- Registration Number
- NCT00395746
- Locations
- 🇯🇵
Novo Nordisk Investigational Site, Tokyo, Japan
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
- Conditions
- Interventions
- First Posted Date
- 2006-10-29
- Last Posted Date
- 2017-03-08
- Lead Sponsor
- Novo Nordisk A/S
- Target Recruit Count
- 400
- Registration Number
- NCT00393718
- Locations
- 🇯🇵
Novo Nordisk Investigational Site, Tokyo, Japan
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
- Conditions
- First Posted Date
- 2006-06-02
- Last Posted Date
- 2017-01-25
- Lead Sponsor
- Novo Nordisk A/S
- Target Recruit Count
- 576
- Registration Number
- NCT00333151
- Locations
- 🇨🇦
Novo Nordisk Investigational Site, Windsor, Canada
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
- Conditions
- First Posted Date
- 2006-05-31
- Last Posted Date
- 2017-01-26
- Lead Sponsor
- Novo Nordisk A/S
- Target Recruit Count
- 584
- Registration Number
- NCT00331851
- Locations
- 🇬🇧
Novo Nordisk Investigational Site, Watford, United Kingdom
To Compare the Effect of Liraglutide When Given Together With Metformin With the Effect of Metformin Given Alone and With the Effect of Glimepiride and Metformin Given Together
- Conditions
- Interventions
- First Posted Date
- 2006-04-26
- Last Posted Date
- 2017-03-07
- Lead Sponsor
- Novo Nordisk A/S
- Target Recruit Count
- 1091
- Registration Number
- NCT00318461
- Locations
- 🇬🇧
Novo Nordisk Investigational Site, Sunbury on Thames, United Kingdom
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
- Conditions
- First Posted Date
- 2006-04-26
- Last Posted Date
- 2017-01-25
- Lead Sponsor
- Novo Nordisk A/S
- Target Recruit Count
- 1041
- Registration Number
- NCT00318422
- Locations
- 🇹🇷
Novo Nordisk Investigational Site, Izmir, Turkey
Drug Development Updates
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