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Ranitidine

Generic Name
Ranitidine
Brand Names
Good Sense Acid Reducer, Wal-zan, Zantac
Drug Type
Small Molecule
Chemical Formula
C13H22N4O3S
CAS Number
66357-35-5
Unique Ingredient Identifier
884KT10YB7

Overview

Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as cimetidine and famotidine. This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of its ability to decrease gastric acid secretion. Ranitidine is often referred to as Zantac, and is available in various forms, including tablet, injection, and effervescent tablet preparations. The prevalence of GERD is thought to be 10-20% in western countries. Ranitidine has proven to be an effective treatment for relieving uncomfortable symptoms of gastric acid associated conditions and is therefore widely used in GERD and other gastric-acid related conditions.

Background

Ranitidine is a commonly used drug, classified as a histamine H2-receptor antagonist, and belongs to the same drug class as cimetidine and famotidine. This drug helps to prevent and treat gastric-acid associated conditions, including ulcers, because of its ability to decrease gastric acid secretion. Ranitidine is often referred to as Zantac, and is available in various forms, including tablet, injection, and effervescent tablet preparations. The prevalence of GERD is thought to be 10-20% in western countries. Ranitidine has proven to be an effective treatment for relieving uncomfortable symptoms of gastric acid associated conditions and is therefore widely used in GERD and other gastric-acid related conditions.

Indication

This drug is used alone or with concomitant antacids for the following conditions: short-term treatment of active duodenal ulcer, treating gastric acid hypersecretion due to Zollinger-Ellison syndrome, systemic mastocytosis, and other conditions that may pathologically raise gastric acid levels. It also used in the short term treatment of active benign gastric ulcers and maintenance therapy of gastric ulcers at a reduced dose. In addition to the above, ranitidine can be used for the treatment of GERD symptoms, treatment of erosive esophagitis (endoscopically diagnosed) and the maintenance of gastric or duodenal ulcer healing.

Associated Conditions

  • Acid Aspiration Syndrome
  • Ankylosing Spondylitis (AS)
  • Duodenal Ulcer
  • Erosive Esophagitis
  • Gastric Ulcer
  • Gastric hypersecretion
  • Gastro-esophageal Reflux Disease (GERD)
  • Healing
  • Heartburn
  • Osteoarthritis (OA)
  • Peptic Ulcer Disease
  • Rheumatoid Arthritis
  • Stress Ulcers
  • Zollinger-Ellison Syndrome
  • Active Duodenal ulcer
  • Benign gastric ulcer healing
  • Benign gastric ulcers
  • Duodenal ulcer healing
  • Post-operative peptic ulcer
  • Recurrent hemorrhage from bleeding ulcers

FDA Approved Products

Ranitidine
Manufacturer:Unit Dose Services
Route:ORAL
Strength:150 mg in 1 1
Approved: 2018/12/07
NDC:50436-6930
Ranitidine
Manufacturer:Carilion Materials Management
Route:ORAL
Strength:15 mg in 1 mL
Approved: 2016/03/18
NDC:68151-2890
Ranitidine Immediate release
Manufacturer:Aphena Pharma Solutions - Tennessee, LLC
Route:ORAL
Strength:150 mg in 1 1
Approved: 2020/01/15
NDC:71610-378
Ranitidine
Manufacturer:NuCarePharmaceuticals, Inc.
Route:ORAL
Strength:150 mg in 1 1
Approved: 2021/02/11
NDC:68071-3248
Ranitidine
Manufacturer:Par Pharmaceutical Inc
Route:ORAL
Strength:150 mg in 1 1
Approved: 2016/08/19
NDC:49884-544

Singapore Approved Products

ZYNOL-150 TABLET 150 mg
Manufacturer:MICRO LABS LTD
Form:TABLET, FILM COATED
Strength:150 mg
Online:Yes
Approved: 1998/10/10
Approval:SIN10248P
HYZAN TABLET 150 mg
Manufacturer:XEPA-SOUL PATTINSON (MALAYSIA) SDN BHD
Form:TABLET, FILM COATED
Strength:150 mg
Online:Yes
Approved: 1998/10/02
Approval:SIN10146P
GASTRIL INJECTION 50 mg/2 ml
Manufacturer:DUOPHARMA (M) SDN BHD
Form:INJECTION
Strength:50 mg/2 ml
Online:Yes
Approved: 1998/09/25
Approval:SIN10081P
APO-RANITIDINE TABLET 150 mg
Manufacturer:APOTEX INC
Form:TABLET, FILM COATED
Strength:150 mg
Online:Yes
Approved: 1991/02/18
Approval:SIN05429P
ACILOC 150 TABLET 150 mg
Manufacturer:CADILA PHARMACEUTICALS LTD
Form:TABLET, FILM COATED
Strength:150 mg
Online:Yes
Approved: 2001/12/26
Approval:SIN11750P

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