MedPath

Aluminum sulfate

Generic Name
Aluminum sulfate
Brand Names
Domeboro, Riarify (previously CHF 5993 Chiesi Farmaceutici S.p.A.), Trixeo Aerosphere
Drug Type
Small Molecule
Chemical Formula
Al2O12S3
CAS Number
10043-01-3
Unique Ingredient Identifier
I7T908772F

Overview

Aluminum (Al), also spelled aluminum, chemical element, a lightweight, silvery-white metal of main Group 13 (IIIa, or boron group) of the periodic table . It is a chemical agent used in water purification, the pH regulation of garden soil, and other commercial or industrial applications. Medically, it is primarily used as a coagulating agent in minor cuts and abrasions as well as deodorant . Aluminum (Al) is ubiquitous and represents the third most common element in the Earth’s crust. It most commonly exists in a combined state with various other elements. Al is found in materials used in the pharmaceutical industry, and in manufactured foodstuffs, cosmetics, and tap water. By overcoming the body barriers, Al may infiltrate into the blood and lead to toxic effects in liver, bone and the central nervous system .

Background

Aluminum (Al), also spelled aluminum, chemical element, a lightweight, silvery-white metal of main Group 13 (IIIa, or boron group) of the periodic table . It is a chemical agent used in water purification, the pH regulation of garden soil, and other commercial or industrial applications. Medically, it is primarily used as a coagulating agent in minor cuts and abrasions as well as deodorant . Aluminum (Al) is ubiquitous and represents the third most common element in the Earth’s crust. It most commonly exists in a combined state with various other elements. Al is found in materials used in the pharmaceutical industry, and in manufactured foodstuffs, cosmetics, and tap water. By overcoming the body barriers, Al may infiltrate into the blood and lead to toxic effects in liver, bone and the central nervous system .

Indication

Solutions containing 5 to 10% aluminum sulfate have been used as local applications to ulcers and to arrest foul discharges from mucous surfaces. Aluminum sulfate is also used in the preparation of aluminum acetate ear drops . It is often purchased over the counter and is available in solid stick or powder form for minor cuts and abrasions after shaving , . Aluminum sulfate is also used as an adjuvant in vaccines .

Associated Conditions

  • Bleeding

Clinical Trials

Title
Posted
Study ID
Phase
Status
Sponsor

No clinical trials found

No clinical trials found for this drug

FDA Approved Products

Product Name
Manufacturer
Route
Strength
Approved
NDC Code
TOPICAL
1347 mg in 2299 mg
2025/03/03
81469-999

EMA Approved Products

Medicine Name
EMA Number
Auth. Holder
Country
Drug Type
Status
Issued
Opinion
Revision
EMEA/H/C/003745
the netherlands
N/A
Authorised
2014/11/19
2014/09/25
16
EMEA/H/C/002348
the netherlands
N/A
Authorised
2014/04/28
N/A
13
EMEA/H/C/004257
Italy
N/A
Authorised
2017/07/17
2017/05/18
9
EMEA/H/C/004245
Sweden
N/A
Authorised
2018/12/18
2018/10/18
8
EMEA/H/C/004882
the netherlands
N/A
Authorised
2020/04/03
2020/01/30
6
EMEA/H/C/004836
Italy
N/A
Withdrawn
2018/04/23
2018/02/22
7
EMEA/H/C/004836
Italy
N/A
Withdrawn
2018/04/23
2018/02/22
7
EMEA/H/C/004983
Sweden
N/A
Authorised
2020/12/09
2020/10/15
6
EMEA/H/C/003890
the netherlands
N/A
Authorised
2014/04/28
N/A
13
EMEA/H/C/003969
the netherlands
N/A
Authorised
2014/11/19
N/A
16

NMPA Approved Products

Product Name
Approval No.
Manufacturer
Dosage Form
Trade Name
Strength
Type
Status
Date
Import

No NMPA products found

No NMPA products found for this drug

PPB Approved Products

Product Name
Registration Code
Company
Category
Sale Type
Reg. Date
HK-68475
Part 1, Schedule 1 & Schedule 3 Poison
POM
2024/12/03
HK-68474
Part 1, Schedule 1 & Schedule 3 Poison
POM
2024/12/03

TGA Approved Products

Product Name
ARTG ID
Sponsor
Status
Reg. Date
Ingredient
80877
Active
2004/05/05
formoterol fumarate dihydrate
115555
Active
2006/02/22
formoterol fumarate dihydrate
295674
Active
2017/12/22
formoterol fumarate dihydrate
60142
Active
1997/11/10
formoterol fumarate dihydrate
177875
Active
2013/06/14
formoterol fumarate dihydrate
267384
Active
2016/12/19
formoterol fumarate dihydrate
408415
Active
2025/03/24
formoterol fumarate dihydrate
267385
Active
2016/12/19
formoterol fumarate dihydrate
60141
Active
1997/11/10
formoterol fumarate dihydrate
396689
Active
2022/12/06
formoterol fumarate dihydrate
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