Isosorbide mononitrate
- Generic Name
- Isosorbide mononitrate
- Brand Names
- Imdur, Ismo, Monoket
- Drug Type
- Small Molecule
- Chemical Formula
- C6H9NO6
- CAS Number
- 16051-77-7
- Unique Ingredient Identifier
- LX1OH63030
- Background
Isosorbide mononitrate is an organic nitrate with vasodilating properties. It is an anti-anginal agent that works by relaxing the smooth muscles of both arteries and veins, but but predominantly veins to reduce cardiac preload. Isosorbide mononitrate is an active metabolite of isosorbide dinitrate. Like other organic nitrates, isosorbide mononitrate acts as ...
- Indication
Isosorbide mononitrate is indicated for the prevention and management of angina pectoris due to coronary artery disease. The onset of action of oral isosorbide mononitrate is not sufficiently rapid to be useful in aborting an acute anginal episode.
- Associated Conditions
- Angina Pectoris
- Associated Therapies
- -
Misoprostol Versus Effox as Cervical Ripening Agent Prior Surgical Evacuation
- Conditions
- Interventions
- First Posted Date
- 2016-04-14
- Last Posted Date
- 2016-04-14
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 90
- Registration Number
- NCT02738177
- Locations
- 🇪🇬
Kasr Elainy Hospital (Cairo University), Cairo, Egypt
Nitric Oxide Donors for Treatment of Isolated Oligohydramnios
- Conditions
- Interventions
- First Posted Date
- 2016-03-18
- Last Posted Date
- 2016-03-18
- Lead Sponsor
- Benha University
- Target Recruit Count
- 100
- Registration Number
- NCT02712125
PK, PD and Safety Comparative Trial of Isosorbide Mononitrate Gel in Healthy Participants and With Anal Fissure
- First Posted Date
- 2016-01-29
- Last Posted Date
- 2017-07-17
- Lead Sponsor
- Biolab Sanus Farmaceutica
- Registration Number
- NCT02667535
Termination Of Anembryonic Pregnancy
- Conditions
- Interventions
- First Posted Date
- 2015-10-09
- Last Posted Date
- 2024-07-31
- Lead Sponsor
- Assiut University
- Registration Number
- NCT02573051
- Locations
- 🇪🇬
Assiut university, Assiut, Egypt
Lacunar Intervention Trial 1 (LACI-1)
- Conditions
- Interventions
- First Posted Date
- 2015-06-25
- Last Posted Date
- 2018-01-19
- Lead Sponsor
- University of Edinburgh
- Target Recruit Count
- 57
- Registration Number
- NCT02481323
- Locations
- 🇬🇧
University of Edinburgh, Edinburgh, United Kingdom
🇬🇧University of Nottingham, Nottingham, United Kingdom
Efficacy and Safety of Monocordil Manufactured by Laboratórios Baldacci
- First Posted Date
- 2014-06-02
- Last Posted Date
- 2014-06-02
- Lead Sponsor
- Laboratórios Baldacci S.A
- Target Recruit Count
- 86
- Registration Number
- NCT02152579
- Locations
- 🇧🇷
Clinicordis, Campinas, SP, Brazil
Nitrate's Effect on Activity Tolerance in Heart Failure With Preserved Ejection Fraction
- First Posted Date
- 2014-02-03
- Last Posted Date
- 2016-11-28
- Lead Sponsor
- Adrian Hernandez
- Target Recruit Count
- 110
- Registration Number
- NCT02053493
- Locations
- 🇺🇸
Lancaster General Hospital, Lancaster, Pennsylvania, United States
🇺🇸University of Pennsylvania Health System, Philadelphia, Pennsylvania, United States
🇺🇸Tufts Medical Center, Boston, Massachusetts, United States
Secondary Prophylaxis After Variceal Bleeding in Non-Responders
- Conditions
- First Posted Date
- 2007-03-21
- Last Posted Date
- 2007-03-21
- Target Recruit Count
- 50
- Registration Number
- NCT00450164
- Locations
- 🇪🇸
Unidad de Sangrantes, HSCSP, Barcelona, Spain
Drug Development Updates
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