MedPath

Dimethyl Sulfoxide

Generic Name
Dimethyl Sulfoxide
Brand Names
Rimso-50
Drug Type
Small Molecule
Chemical Formula
C2H6OS
CAS Number
67-68-5
Unique Ingredient Identifier
YOW8V9698H
Background

A highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during cryopreservation. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.

Indication

⑴作透皮促进剂,常用于氢化可的松、地塞米松、氟轻松、睾酮、胰岛素、肝素、维生素类、水杨酸类等的制剂。5%以下无透皮作用,5%以上随浓度增加而作用增强,常用其30%~50%水溶液。目前仅供外用。 ⑵作溶剂和防冻剂,60%水溶液能降低冰点至-80℃。

Associated Conditions
Interstitial Cystitis
Associated Therapies
Extravasation of chemotherapy drugs
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