GS-441524
- Generic Name
- GS-441524
- Drug Type
- Small Molecule
- Chemical Formula
- C12H13N5O4
- CAS Number
- 1191237-69-0
- Unique Ingredient Identifier
- 1BQK176DT6
- Background
GS-441524 is an adenosine nucleotide analog antiviral, similar to remdesivir. This molecule was patented in 2009. In vitro studies of GS-441524 have determined it has a higher EC than remdesivir against a number of viruses, meaning GS-441524 is less potent. GS-441524 continues to be studied in the treatment of Feline Infectious Peritonitis Virus, a coronavirus that only infects cats.
GS-441524 for COVID-19 SAD, FE, and MAD Study in Healthy Subjects
- First Posted Date
- 2024-02-23
- Last Posted Date
- 2025-02-14
- Lead Sponsor
- National Center for Advancing Translational Sciences (NCATS)
- Target Recruit Count
- 70
- Registration Number
- NCT06274853
First-in-Human Study of Orally Administered GS-441524 for COVID-19
- First Posted Date
- 2021-04-26
- Last Posted Date
- 2021-08-10
- Lead Sponsor
- Copycat Sciences LLC
- Target Recruit Count
- 1
- Registration Number
- NCT04859244
- Locations
- 🇺🇸
Copycat Sciences Study Site, Houston, Texas, United States
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