Flunarizine

Generic Name
Flunarizine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C26H26F2N2
CAS Number
52468-60-7
Unique Ingredient Identifier
R7PLA2DM0J
Background

Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. It is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.

Indication

Used in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy.

Associated Conditions
Severe Migraine
Associated Therapies
-

Comparison of the Effectiveness of First-line Preventive Treatment of Migraine in Primary Care

First Posted Date
2024-07-12
Last Posted Date
2024-07-12
Lead Sponsor
Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Target Recruit Count
460
Registration Number
NCT06499116

Decoding Pain Sensitivity in Migraine With Multimodal Brainstem-based Neurosignature

Phase 4
Recruiting
Conditions
Interventions
First Posted Date
2021-01-11
Last Posted Date
2021-04-14
Lead Sponsor
Taipei Veterans General Hospital, Taiwan
Target Recruit Count
600
Registration Number
NCT04702971
Locations
🇨🇳

Headache Center, Teipei Veterans General Hospital, Taipei, Taiwan

Comparison of Therapeutic Effects of Greater Occipital Nerve Block, Topiramate, and Flunarizine on Episodic Migraine

First Posted Date
2018-10-19
Last Posted Date
2020-01-21
Lead Sponsor
Ataturk University
Target Recruit Count
120
Registration Number
NCT03712917
Locations
🇹🇷

Ataturk University Resarch Hospital, Erzurum, Turkey

Flunarizine Versus Topiramate for Chronic Migraine Prophylaxis

Phase 4
Completed
Conditions
Interventions
First Posted Date
2015-12-24
Last Posted Date
2015-12-24
Lead Sponsor
Taipei Veterans General Hospital, Taiwan
Target Recruit Count
62
Registration Number
NCT02639598

Efficacy and Tolerability of Flunarizine for the Treatment of Schizophrenia: Comparison With Haloperidol

Phase 4
Completed
Conditions
First Posted Date
2008-08-22
Last Posted Date
2008-08-22
Lead Sponsor
Ambulatório de Bipolaridade
Target Recruit Count
70
Registration Number
NCT00740259
Locations
🇧🇷

Universidade Federal de São Paulo, São Paulo, SP, Brazil

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