Cevimeline

Generic Name
Cevimeline
Brand Names
Evoxac
Drug Type
Small Molecule
Chemical Formula
C10H17NOS
CAS Number
107233-08-9
Unique Ingredient Identifier
K9V0CDQ56E
Background

Cevimeline is a parasympathomimetic agent that act as an agonist at the muscarinic acetylcholine receptors M1 and M3. It is indicated by the Food and Drug Administration for the treatment of dry mouth associated with Sjögren's syndrome.

Indication

用于治疗各型青光眼。FDA批准用于干燥综合征和放疗引起的口干症。

Associated Conditions
Dry Mouth
Associated Therapies
-
Clinical Trials
Related News

Crossover Bioequivalence Study of Cevimeline 30 mg Capsules Under Fed Conditions

Early Phase 1
Completed
Conditions
Dry Mouth
Interventions
Drug: Cevimeline
First Posted Date
2013-07-19
Last Posted Date
2018-01-23
Lead Sponsor
Roxane Laboratories
Target Recruit Count
27
Registration Number
NCT01903109
Locations
🇺🇸

Novum Pharmaceutical Research Services, Las Vegas, Nevada, United States

Crossover Bioequivalence Study of Cevimeline 30 mg Capsules Under Fasted Conditions

Early Phase 1
Completed
Conditions
Dry Mouth
Interventions
Drug: Cevimeline
First Posted Date
2013-07-19
Last Posted Date
2018-01-23
Lead Sponsor
Roxane Laboratories
Target Recruit Count
26
Registration Number
NCT01903122
Locations
🇺🇸

Novum Pharmaceutical Research Services, Las Vegas, Nevada, United States

Efficacy of Cevimeline Versus Pilocarpine in the Secretion of Saliva

Not Applicable
Completed
Conditions
Dry Mouth
Interventions
Drug: Cevimeline
Drug: Pilocarpine
First Posted Date
2012-09-21
Last Posted Date
2018-06-04
Lead Sponsor
University of Kentucky
Target Recruit Count
15
Registration Number
NCT01690052
Locations
🇺🇸

University of Kentucky Orofacial Pain Center College of Dentistry, Lexington, Kentucky, United States

Study of the Effectiveness of Cevimeline on Oral Health in Patients With Radiation Induced Xerostomia

Phase 4
Completed
Conditions
Xerostomia
Interventions
Drug: Cevimeline
First Posted Date
2007-04-24
Last Posted Date
2014-05-22
Lead Sponsor
American Academy of Otolaryngology-Head and Neck Surgery Foundation
Target Recruit Count
54
Registration Number
NCT00466388
Locations
🇺🇸

Fauquier ENT Consultants, Warrenton, Virginia, United States

🇺🇸

Commonwealth Ear, Nose and Throat, Louisville, Kentucky, United States

🇺🇸

Associated Otolaryngologist, Palmyra, Pennsylvania, United States

and more 3 locations
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