Capsaicin

Generic Name
Capsaicin
Brand Names
Capzasin Quick Relief, Capzasin-HP, Castiva Warming, Dendracin Neurodendraxcin, Lidopro, Medi-derm, Medi-derm With Lidocaine, Medrox, Qutenza, Rematex, Xoten-C, Zostrix
Drug Type
Small Molecule
Chemical Formula
C18H27NO3
CAS Number
404-86-4
Unique Ingredient Identifier
S07O44R1ZM
Background

Capsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. The most recent capsaicin F...

Indication

The capsaicin 8% patch is indicated in the treatment of neuropathic pain associated with post-herpetic neuralgia. There are multiple topical capsaicin formulations available, including creams and solutions, indicated for temporary analgesia in muscle and join pain as well as neuropathic pain.

Associated Conditions
Back Pain Lower Back, Back pain, Bursitis, Contusions, Inflammatory Reaction caused by Rheumatism, Muscle Cramps, Musculoskeletal Pain, Neuropathic Pain, Osteoarthritis (OA), Pain caused by Rheumatism, Periarthritis, Soft Tissue Injury, Tendinitis, Acute nonspecific tenosynovitis, Articular inflammation
Associated Therapies
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Analgesic Efficacy of Capsaicin 8% Patch (QUTENZA®) in Coccygodygnia

Not yet recruiting
Conditions
First Posted Date
2023-08-09
Last Posted Date
2023-08-09
Lead Sponsor
Nantes University Hospital
Target Recruit Count
106
Registration Number
NCT05983263

Capsaicin 179 mg Patch Versus Oral Duloxetine in Patients With Chemotherapy-induced Peripheral Neuropathy

First Posted Date
2023-05-03
Last Posted Date
2024-08-02
Lead Sponsor
Institut Cancerologie de l'Ouest
Target Recruit Count
274
Registration Number
NCT05840562
Locations
🇫🇷

Centre François Baclesse, Caen, France

🇫🇷

CHU Grenoble, Grenoble, France

🇫🇷

Centre Léon Bérard, Lyon, France

and more 7 locations

Capsaicin for Cerebral Perfusion Augmentation

Phase 2
Completed
Conditions
Interventions
First Posted Date
2022-09-16
Last Posted Date
2023-03-14
Lead Sponsor
Instituto Mexicano del Seguro Social
Target Recruit Count
20
Registration Number
NCT05543837
Locations
🇲🇽

Centenario Hospital Miguel Hidalgo, Aguascalientes, Mexico

Study With Two Capsaicin Topic Treatments in Diabetic Neuropathy.

Phase 3
Completed
Conditions
Interventions
First Posted Date
2021-08-31
Last Posted Date
2021-09-14
Lead Sponsor
Arafarma Group, S.A.
Target Recruit Count
161
Registration Number
NCT05029297

Capsaicin to Prevent Delayed Chemotherapy Induced Nausea and Vomiting (CapCIN)

First Posted Date
2021-06-08
Last Posted Date
2022-05-20
Lead Sponsor
Christian Medical College, Vellore, India
Target Recruit Count
160
Registration Number
NCT04918069
Locations
🇮🇳

Christian Medical College, Vellore, Tamilnadu, India

Evaluation of Peripheral Itch Mechanisms Following Injection of Morphine (Second Sub-Project)

First Posted Date
2021-01-07
Last Posted Date
2022-01-27
Lead Sponsor
Aalborg University
Target Recruit Count
26
Registration Number
NCT04700007
Locations
🇩🇰

Mech-Sense, Medicinsk Gastroenterologisk ambulatorium, Medicineshus, Aalborn Universitethospitalet, AAlborg, Nordjylland, Denmark

Capsaicin for Cerebral Perfusion Augmentation.

Phase 1
Completed
Conditions
Interventions
First Posted Date
2020-09-11
Last Posted Date
2020-09-11
Lead Sponsor
Juan Manuel Marquez Romero
Target Recruit Count
30
Registration Number
NCT04545892
Locations
🇲🇽

Unidad de Medicina de Alta Especialidad en Torre Médica CMQ, Aguascalientes, Ags., Mexico

Capsaicin for the Treatment of Cannabinoid Hyperemesis Syndrome

First Posted Date
2020-02-25
Last Posted Date
2024-10-18
Lead Sponsor
University of Virginia
Target Recruit Count
20
Registration Number
NCT04283292
Locations
🇺🇸

UVA Health System, Charlottesville, Virginia, United States

Quantitative Ultrasound Response of Capsaicin

First Posted Date
2019-05-10
Last Posted Date
2020-12-03
Lead Sponsor
Toronto Rehabilitation Institute
Target Recruit Count
20
Registration Number
NCT03944889
Locations
🇨🇦

Toronto Rehabilitation Institute, Toronto, Ontario, Canada

Evaluation in the Treatment of Neuropathic Pain Post Breast Surgery

Phase 3
Completed
Conditions
Interventions
First Posted Date
2019-01-07
Last Posted Date
2023-08-01
Lead Sponsor
Institut Cancerologie de l'Ouest
Target Recruit Count
140
Registration Number
NCT03794388
Locations
🇫🇷

Centre Leon Berard, Lyon, France

🇫🇷

Ch Valenciennes, Valenciennes, France

🇫🇷

Institut de Cancerologie de L'Ouest, Angers, France

and more 8 locations
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