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Ripasudil

Generic Name
Ripasudil
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C15H18FN3O2S
CAS Number
223645-67-8
Unique Ingredient Identifier
11978226XX
Background

Ripasudil, as hydrochloride hydrate (K-115), is a specifc Rho-associated coiled-coil containing protein kinase (ROCK) inhibitor used for the treatment of glaucoma and ocular hypertension. It was first approved for treatment in Japan in September 2014. This medication is available in the form of a 0.4% eye drop solution under the brand name Glanatec. Ripasudil is a well tolerated medication that is used when other drugs have been proven to be non-effective or cannot be administered.

Indication

Ripasudil has been proven to be effective in the twice daily treatment of glaucoma and ocular hypertension. It is currently in studies to be approved for both diabetic retinopathy and diabetic macular oedema.

Associated Conditions
Ocular Hypertension, Open Angle Glaucoma (OAG)
Associated Therapies
-
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