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Nebicapone

Generic Name
Nebicapone
Drug Type
Small Molecule
Chemical Formula
C14H11NO5
CAS Number
274925-86-9
Unique Ingredient Identifier
NM2KXJ990T
Background

Nebicapone is under investigation in clinical trial NCT03097211 (Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics With a Single-dose of Levodopa/Benserazide 200/50 mg or With a Single-dose of Levodopa/Benserazide 200/50 mg Plus a Single-dose of Nebicapone 150 mg).

Efficacy and Tolerability of Nebicapone in Parkinson's Disease Patients With "Wearingoff" Phenomenon

Phase 2
Completed
Conditions
Parkinson Disease
Interventions
Drug: Levodopa/DDCI
Drug: Placebo
First Posted Date
2017-04-06
Last Posted Date
2017-04-06
Lead Sponsor
Bial - Portela C S.A.
Target Recruit Count
254
Registration Number
NCT03103399

Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics With a Single-dose of Levodopa/Benserazide 200/50 mg or With a Single-dose of Levodopa/Benserazide 200/50 mg Plus a Single-dose of Nebicapone 150 mg

Phase 1
Completed
Conditions
Parkinson Disease
Interventions
Drug: Placebo
Drug: Madopar® 250
First Posted Date
2017-03-31
Last Posted Date
2017-03-31
Lead Sponsor
Bial - Portela C S.A.
Target Recruit Count
38
Registration Number
NCT03097211
Locations
🇵🇹

Human Pharmacology Unit (UFH) - BIAL - Portela & Cª, SA, S. Mamede do Coronado, Portugal

Study to Investigate the Tolerability, Steady-state Pharmacokinetics and Erythrocyte COMT Inhibition of BIA 3-202

Phase 1
Completed
Conditions
Parkinson's Disease
Interventions
Drug: Placebo
First Posted Date
2016-05-13
Last Posted Date
2016-05-13
Lead Sponsor
Bial - Portela C S.A.
Target Recruit Count
22
Registration Number
NCT02772627
Locations
🇵🇹

Human Pharmacology Unit - BIAL - Portela & Ca, S.A., S. Mamede do Coronado, Portugal

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