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Clinical and Radiographic Evaluation of Silver Diamine Fluoride Versus Mineral Trioxide Aggregate in Indirect Pulp Capping

A randomized clinical trial compared the effectiveness of Silver Diamine Fluoride (SDF) and Mineral Trioxide Aggregate (MTA) in indirect pulp capping (IPC) for first permanent molars with deep carious lesions. Both materials showed a 100% clinical and radiographic success rate after 12 months, with no significant differences in dentin bridge thickness. The study highlights the potential of SDF as a cost-effective alternative to MTA for IPC in permanent teeth, despite the need for further research.

The First permanent molar (FPM) is crucial for oral function but is highly susceptible to dental decay. Indirect Pulp Capping (IPC) is preferred for treating deep caries without irreversible pulp alterations, aiming to preserve pulp vitality. This study evaluated the clinical and radiographic outcomes of using Silver Diamine Fluoride (SDF) versus Mineral Trioxide Aggregate (MTA) in IPC for permanent molars.
Materials and Methods:
  • Study Design: Randomized clinical trial adhering to CONSORT guidelines.
  • Sample Size: 30 first permanent molars were randomly allocated to SDF (intervention) and MTA (control) groups.
  • Eligibility Criteria: Included vital deeply carious first permanent mandibular molars in children aged 9-14 years.
  • Outcomes: Clinical and radiographic success rates, dentin bridge thickness, and post-operative pain were assessed over 12 months.
Results:
  • Both SDF and MTA groups showed a 100% clinical and radiographic success rate after 12 months.
  • No significant differences were found in dentin bridge thickness between the two groups.
  • Post-operative pain was minimal and subsided in follow-up visits.
Conclusion: The study suggests that SDF is as effective as MTA for IPC in permanent molars with deep carious lesions, offering a cost-effective alternative. However, further research is needed to confirm these findings and explore the long-term outcomes of SDF use in IPC.
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NCT05425368Unknown StatusNot Applicable
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Reference News

[1]
Clinical and radiographic evaluation of silver diamine fluoride versus mineral trioxide ... - Nature
nature.com · Jan 9, 2025

The study compares Silver Diamine Fluoride (SDF) and Mineral Trioxide Aggregate (MTA) for Indirect Pulp Capping (IPC) in...

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