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Sacubitril/Valsartan Study Explores Glucose Metabolism Effects in Healthy African Americans

• A research study is investigating the impact of sacubitril/valsartan on glucose metabolism in healthy African American adults aged 18-60. • The trial excludes individuals with a history of diabetes, heart disease, or kidney problems to focus on baseline metabolic effects. • Participants will undergo exercise and blood sample collection while taking sacubitril/valsartan, receiving $675 compensation for full participation. • The study aims to understand how sacubitril/valsartan, a blood pressure-related medication, affects sugar handling in this specific population.

A clinical trial is underway at the University of Alabama at Birmingham (UAB) to examine the effects of sacubitril/valsartan on glucose metabolism in healthy African American adults. The study seeks to understand how this medication, commonly used for blood pressure management, influences the way the body processes sugar in individuals without pre-existing conditions like diabetes.

Study Design and Eligibility

The trial is enrolling healthy African American men and women between the ages of 18 and 60. Participants must have no history of diabetes, heart disease, or kidney problems to ensure a focus on the medication's effects on baseline glucose metabolism. The study protocol involves participants performing exercise, taking sacubitril/valsartan, and providing blood samples for analysis.

Sacubitril/Valsartan and Glucose Metabolism

Sacubitril/valsartan is a combination medication primarily used to treat heart failure and hypertension. The trial aims to explore its potential impact on glucose metabolism, an area of increasing research interest. Understanding how sacubitril/valsartan affects glucose handling in healthy individuals could provide insights into its broader metabolic effects and potential applications.

Participant Compensation

Participants who complete all study visits will receive $675 as compensation for their time and effort. This compensation aims to encourage participation and ensure adequate representation in the study.

Contact Information

Individuals interested in participating in the study are encouraged to contact Tiffany at 205-934-0534 or via email at nauticalstudy@uabmc.edu.
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Reference News

[1]
Are you a healthy African American between the ages of 18 and 60? - The Reporter | UAB
uab.edu · Oct 23, 2024

Eligible healthy African American men and women without diabetes, heart disease, or kidney problems can participate in a...

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