Largest study to date of high-dose methotrexate associated ...
Glucarpidase treatment in HDMTX-AKI patients showed higher kidney recovery odds, reduced mortality, and faster recovery from neutropenia and liver enzyme normalization compared to non-treated patients. The study, the largest on HDMTX-AKI, supports early glucarpidase use, especially within the first 60 hours and in severe AKI cases.
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Largest study to date of high-dose methotrexate associated ...
Glucarpidase treatment in HDMTX-AKI patients showed higher kidney recovery odds, reduced mortality, and faster recovery from neutropenia and liver enzyme normalization compared to non-treated patients. The study, the largest on HDMTX-AKI, supports early glucarpidase use, especially within the first 60 hours and in severe AKI cases.