Clinical Trial News
New Insights into Bladder Cancer Screening and Awareness Campaign Launch
Recent studies have provided new insights into bladder cancer screening, showing the benefits of early detection. Additionally, a new awareness campaign has been launched by the AUA Foundation and BCAN, with actor Tate Donovan as the national spokesperson.
HonorHealth's Cancer Research Program: A Leader in Clinical Trials and Treatment Innovation
HonorHealth's cancer research program at the HonorHealth Research Institute is at the forefront of cancer treatment innovation, offering patients access to clinical trials from phase I to IV. The program emphasizes early drug development, providing patients with new medications and treatment approaches before they are widely available. With a comprehensive support system, including navigators and concierge services, HonorHealth is dedicated to advancing medical care and improving patient outcomes.
Ceftriaxone Shows Promise in Alleviating Fatigue in Post-Lyme Disease Syndrome
• A randomized, double-blind, placebo-controlled trial assessed the efficacy of ceftriaxone in treating post-Lyme disease syndrome (PLS) patients with persistent fatigue.
• Ceftriaxone therapy demonstrated a significant improvement in fatigue compared to placebo in PLS patients, as measured by a fatigue questionnaire.
• The study found no beneficial effect of ceftriaxone on cognitive function or experimental measures of persistent infection in PLS patients.
• Due to adverse events and the improvement of only fatigue, the study does not support routine antibiotic therapy with ceftriaxone for PLS patients.
FDA Approves Expanded Use of MED-EL Cochlear Implant System
The FDA has approved the MED-EL Cochlear Implant System for a broader range of patients, including adults with bilateral moderate to profound sensorineural hearing loss who benefit minimally from hearing aids.
Home-Based Exercise Program Significantly Reduces Knee Pain, Study Finds
A two-year study involving 786 participants with knee pain found that a simple home-based exercise program significantly reduces knee pain and improves physical function. The study highlights the importance of exercise adherence for pain reduction and suggests that social support alone does not improve health outcomes.
Culturally Tailored Interventions Boost Cervical Cancer Screening Among Chinese Women in North America
A randomized controlled trial demonstrates that culturally and linguistically appropriate interventions significantly increase Pap testing rates among Chinese women in North America, highlighting the effectiveness of outreach worker visits and direct mail strategies.
Intensive Chemo Shows Promise in Relapsed Ovarian Cancer
• A new intensive chemotherapy regimen demonstrates high effectiveness in treating women with relapsed ovarian cancer after initial chemotherapy failure.
• The treatment, combining cisplatin and etoposide, achieved an 80% tumor shrinkage rate, with 43% of patients showing complete remission.
• The intensive regimen, involving weekly cisplatin administration, proved more effective than standard therapies, offering new hope for patients with limited options.
• Researchers noted the treatment was well-tolerated, with manageable side effects, and the drugs are readily available for immediate patient benefit.
Early Antithymocyte Globulin Therapy Enhances Survival in Steroid-Resistant Acute GVHD Patients
A study reviewing the treatment of 79 hematopoetic stem cell transplant patients with steroid-resistant acute GVHD using equine antithymocyte globulin (ATG) showed a 32% survival rate at one year. The therapy was particularly effective in patients with skin GVHD and early signs of steroid resistance.
ASCO 2024: Lenvatinib plus Pembrolizumab Shows Superiority Over Sunitinib in Advanced Renal Cell Carcinoma
At the 2024 ASCO Annual Meeting, Dr. Viktor Grünwald presented findings from the CLEAR trial, highlighting the efficacy of lenvatinib plus pembrolizumab over sunitinib in treating advanced clear cell renal cell carcinoma. The combination therapy demonstrated significant improvements in overall survival, prolonged time to tumor progression across various organs, and a lower median tumor burden at disease progression.
Regional Chemotherapy for Liver Metastases of Colorectal Cancer Shows Varied Perfusion Patterns
A study involving 82 patients with liver metastases from colorectal cancer treated with continuous chemotherapy via hepatic artery infusion pumps revealed varied liver perfusion patterns. While 70% of patients showed homogeneous liver perfusion, 24% had distinct inhomogeneities, and 6% exhibited selective perfusion of one hepatic lobe, impacting the response to therapy.