mRNA Vaccines: How Moderna and Pfizer-BioNTech Revolutionized COVID-19 Immunization
• Moderna and Pfizer-BioNTech developed mRNA-based COVID-19 vaccines with efficacy rates exceeding 90%, representing a breakthrough in vaccine technology during the pandemic.
• Both vaccines use lipid nanoparticle technology to deliver mRNA instructions that teach cells to produce the coronavirus spike protein, triggering a protective immune response without causing infection.
• The vaccines require different storage conditions, with Pfizer's needing ultra-cold temperatures of -94°F (-70°C) while Moderna's remains stable at -4°F (-20°C), affecting global distribution logistics.