A Positron Emission Tomography (PET) Study to Investigate P2X7 Receptor Occupancy by JNJ-55308942 Using [18F]-JNJ-64413739
- First Posted Date
- 2018-02-19
- Last Posted Date
- 2025-04-27
- Lead Sponsor
- Janssen-Cilag International NV
- Target Recruit Count
- 13
- Registration Number
- NCT03437590
- Locations
- π§πͺ
UZ Leuven Gasthuisberg, Leuven, Belgium
A Study to Evaluate the Effect of Multiple Oral Doses of JNJ-42847922 on the Steady-state Pharmacokinetics of an Oral Contraceptive Containing Ethinyl Estradiol and Levonorgestrel in Healthy Female Adult Participants
Phase 1
Completed
- Conditions
- Healthy
- Interventions
- First Posted Date
- 2017-08-15
- Last Posted Date
- 2025-04-27
- Lead Sponsor
- Janssen-Cilag International NV
- Target Recruit Count
- 24
- Registration Number
- NCT03249402
- Locations
- π§πͺ
SGS Life Science Services, Antwerpen, Belgium
A Safety Study of Ustekinumab in the Treatment of Pediatric Participants Aged 6 Years and Older With Moderate to Severe Plaque Psoriasis
- First Posted Date
- 2017-07-14
- Last Posted Date
- 2025-05-23
- Lead Sponsor
- Janssen-Cilag International NV
- Target Recruit Count
- 133
- Registration Number
- NCT03218488
- Locations
- π¦πΉ
Uniklinik Graz, Graz, Austria
π§πͺUCL Hopital Saint-Luc, Bruxelles, Belgium
π§πͺUZ Leuven, Leuven, Belgium
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of JNJ-55308942 in Healthy Male and Female Participants
Phase 1
Completed
- Conditions
- Healthy
- Interventions
- Drug: JNJ-55308942 0.5 mgDrug: JNJ-55308942 12 mgDrug: JNJ-55308942 100 mgDrug: JNJ-55308942 1.5 mgDrug: JNJ-55308942 4 mgDrug: JNJ-55308942 36 mgDrug: Placebo
- First Posted Date
- 2017-05-12
- Last Posted Date
- 2025-04-27
- Lead Sponsor
- Janssen-Cilag International NV
- Target Recruit Count
- 98
- Registration Number
- NCT03151486
- Locations
- π§πͺ
Clinical Pharmacology Unit, Merksem, Belgium
A Phase 1 Study to Evaluate the Effect of the Organic Anion Transporter Inhibitor Probenecid on the Pharmacokinetics of JNJ-64041575 in Healthy Adults
- First Posted Date
- 2017-04-10
- Last Posted Date
- 2018-08-13
- Lead Sponsor
- Janssen-Cilag International NV
- Target Recruit Count
- 18
- Registration Number
- NCT03105986
- Locations
- π©πͺ
CharitΓ© Research Organisation GmbH, Berlin, Germany
A Study to Investigate P2X7 Receptor Occupancy by JNJ-54175446 With the Newly Developed P2X7 Receptor Positron Emission Tomography (PET) Tracer 18F-JNJ-64413739
- First Posted Date
- 2017-03-23
- Last Posted Date
- 2025-04-27
- Lead Sponsor
- Janssen-Cilag International NV
- Target Recruit Count
- 16
- Registration Number
- NCT03088644
- Locations
- π§πͺ
UZ Leuven, Leuven, Belgium
A Study to Assess the Relative Oral Bioavailability of a Single Dose of JNJ-63623872/Oseltamivir Fixed-dose Combination Tablet and Single Agent Concept Formulations of JNJ-63623872 Compared to Their Respective Reference Formulation in Healthy Adult Participants
- First Posted Date
- 2017-01-18
- Last Posted Date
- 2017-05-25
- Lead Sponsor
- Janssen-Cilag International NV
- Target Recruit Count
- 45
- Registration Number
- NCT03023852
- Locations
- π§πͺ
SGS Life Science Services, Antwerp, Belgium
Safety, Tolerability, Pharmacokinetic and Absolute Bioavailability Study of JNJ-63623872 Administered as an Intravenous Infusion and a 600-Milligram (mg) Oral Dose in Healthy Adults
- First Posted Date
- 2016-08-09
- Last Posted Date
- 2018-01-30
- Lead Sponsor
- Janssen-Cilag International NV
- Target Recruit Count
- 66
- Registration Number
- NCT02860806
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-48816274
- First Posted Date
- 2016-08-02
- Last Posted Date
- 2025-04-27
- Lead Sponsor
- Janssen-Cilag International NV
- Target Recruit Count
- 90
- Registration Number
- NCT02852395
- Locations
- π¬π§
University of Surrey, Guildford, United Kingdom
π¬π§Quotient Clinical Limited, United Kingdom, United Kingdom
Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-61393215 in Healthy Participants
- First Posted Date
- 2016-06-24
- Last Posted Date
- 2025-04-27
- Lead Sponsor
- Janssen-Cilag International NV
- Target Recruit Count
- 80
- Registration Number
- NCT02812251