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CENTRE GEORGES FRANCOIS LECLERC

🇫🇷France
Ownership
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Employees
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Market Cap
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Website

Study Evaluating the Safety and the Efficacy of Combination of Atezolizumab, Tiragolumab and and Stereotactic Body Radiation Therapy in Patients With Oligometastatic Multiorgan (IMMUNOs-SBRT)

Phase 1
Recruiting
Conditions
Metastatic Bladder Cancer
Metastatic Non Small Cell Lung Cancer
Metastatic Renal Cell Carcinoma
Metastatic Head and Neck Cancer
Interventions
Drug: Atezolizumab 60 MG/1 ML Intravenous Solution [TECENTRIQ]
Drug: Tiragolumab
Radiation: Stereotactic body radiation therapy (SBRT)
First Posted Date
2022-02-28
Last Posted Date
2023-10-17
Lead Sponsor
Centre Georges Francois Leclerc
Target Recruit Count
92
Registration Number
NCT05259319
Locations
🇫🇷

Centre Georges François Leclerc (CGFL), Dijon, Bourgogne, France

Evaluation of Efficacy of Trifluridine/Tipiracil Plus an Anti-IL-1α True Human Antibody Versus Trifluridine/Tipiracil Plus Placebo in Metastatic Colorectal Cancer Patients After Failure of Oxaliplatin, Irinotecan, Fluoropyrimidine

Phase 1
Recruiting
Conditions
Metastatic Colorectal Cancer
Interventions
Drug: trifluridine/tipiracil + placebo
Drug: trifluridine/tipiracil + XB2001
First Posted Date
2022-01-21
Last Posted Date
2024-02-14
Lead Sponsor
Centre Georges Francois Leclerc
Target Recruit Count
160
Registration Number
NCT05201352
Locations
🇫🇷

ICO Angers, Angers, France

🇫🇷

Institut Sainte Catherine, Avignon, France

🇫🇷

CHU Jean Minjoz, Besançon, France

and more 11 locations

Value of Information of Secondary dAta in ONCOGEnetics

Conditions
Secondary Fundings
Cancer
Genetic Predisposition
First Posted Date
2021-07-22
Last Posted Date
2021-07-22
Lead Sponsor
Centre Georges Francois Leclerc
Target Recruit Count
70
Registration Number
NCT04972409
Locations
🇫🇷

Centre Georges Francois Leclerc, Dijon, France

Modifications in Retinal Microvascularization With Targeted Anti-angiogenic Therapy in Colorectal Cancer

Not Applicable
Recruiting
Conditions
Colorectal Cancer
Interventions
Other: OCT- Angiographie
First Posted Date
2021-07-07
Last Posted Date
2024-02-13
Lead Sponsor
Centre Georges Francois Leclerc
Target Recruit Count
30
Registration Number
NCT04952688
Locations
🇫🇷

Centre Georges François Leclerc, Dijon, France

🇫🇷

CHU de Dijon, Dijon, France

Assessment of Health Related Quality of Life in Women Who Underwent Breast Reconstruction After Radical Surgery

Recruiting
Conditions
Breast Cancer
First Posted Date
2021-06-24
Last Posted Date
2021-06-24
Lead Sponsor
Centre Georges Francois Leclerc
Target Recruit Count
200
Registration Number
NCT04938505
Locations
🇫🇷

Centre Georges Francois Leclerc, Dijon, France

Mechanisms of Anti COVID-19 Humoral and Cellular Immune Response After Vaccination in a Sample of Patients and Salaried Staff From a French Anti-cancer Center

Not Applicable
Completed
Conditions
Cancer
Interventions
Biological: serology and ELISPOT test
Biological: serology
First Posted Date
2021-06-23
Last Posted Date
2023-10-11
Lead Sponsor
Centre Georges Francois Leclerc
Target Recruit Count
539
Registration Number
NCT04935528
Locations
🇫🇷

Centre Georges Francois Leclerc, Dijon, France

Immunomonitoring of Breast Cancer Patients During Systemic Treatment

Not Applicable
Recruiting
Conditions
Breast Cancer
Interventions
Other: blood sample
First Posted Date
2021-06-14
Last Posted Date
2023-10-17
Lead Sponsor
Centre Georges Francois Leclerc
Target Recruit Count
150
Registration Number
NCT04925856
Locations
🇫🇷

Centre Georges Francois Leclerc, Dijon, France

🇫🇷

CHRU Jean Minjoz, Besançon, France

Evaluation of the Efficacy and the Safety of a Stereotaxic Prostatic Radiotherapy Delivered With Linac MRI, in Patients With Prostate Adenocarcinoma

Not Applicable
Active, not recruiting
Conditions
Adenocarcinoma of the Prostate
Interventions
Radiation: Stereotactic Radiotherapy with Linac MRI
First Posted Date
2021-06-01
Last Posted Date
2024-02-13
Lead Sponsor
Centre Georges Francois Leclerc
Target Recruit Count
68
Registration Number
NCT04909294
Locations
🇫🇷

Centre Georges François Leclerc, Dijon, France

Immuno Monitoring in Patient With Epithelial Ovarian Cancer Eligible to PARP Inhibitors

Active, not recruiting
Conditions
Ovarian Cancer
Interventions
Biological: blood samples
First Posted Date
2020-12-19
Last Posted Date
2023-12-07
Lead Sponsor
Centre Georges Francois Leclerc
Target Recruit Count
50
Registration Number
NCT04675320
Locations
🇫🇷

Centre Georges Francois Leclerc, Dijon, France

🇫🇷

CHRU Jean Minjoz, Besançon, France

Exome Analysis (Complexe vs Simple) to Help the Therapeutic Decision for the Precision Medicine

Phase 2
Recruiting
Conditions
Cancer
Interventions
Genetic: Exome analysis
First Posted Date
2020-11-04
Last Posted Date
2023-10-23
Lead Sponsor
Centre Georges Francois Leclerc
Target Recruit Count
2518
Registration Number
NCT04614480
Locations
🇫🇷

CHRU Jean Minjoz, Besançon, France

🇫🇷

Institut Bergonie, Bordeaux, France

🇫🇷

CHU Amiens Picardie, Amiens, France

and more 6 locations
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