MedPath

Tiragolumab

Generic Name
Tiragolumab
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
1918185-84-8
Unique Ingredient Identifier
6XG22YQM2Z
Background

Tiragolumab is under investigation in clinical trial NCT04513925 (A Study of Atezolizumab and Tiragolumab Compared With Durvalumab in Participants With Locally Advanced, Unresectable Stage III Non-small Cell Lung Cancer (NSCLC)).

Associated Conditions
-
Associated Therapies
-

A Phase 2 Clinical Trial Evaluating the Efficacy and Safety of Dual Immune Checkpoint Inhibition With Anti-PD-L1 (Atezolizumab) and Anti-TIGIT (Tiragolumab) in Cancer of Unknown Primary

Phase 2
Not yet recruiting
Conditions
Cancer
Interventions
First Posted Date
2024-12-31
Last Posted Date
2024-12-31
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
35
Registration Number
NCT06754501
Locations
🇺🇸

The University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States

Immunotherapies in Combination With Stereotactic Body Radiation Radiotherapy in Microsatellite Stable (MSS) Metastatic Colorectal Cancer (mCRC)

Phase 2
Not yet recruiting
Conditions
Microsatellite Stable Metastatic Colorectal Cancer
Metastatic Colorectal Cancer
Colorectal Cancer
Interventions
Biological: Tiragolumab
Biological: Atezolizumab
Radiation: Stereotactic Body Radiation Therapy (SBRT)
First Posted Date
2024-09-19
Last Posted Date
2025-01-03
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
36
Registration Number
NCT06603818
Locations
🇺🇸

National Institutes of Health Clinical Center, Bethesda, Maryland, United States

Testing the Combination of Anti-cancer Drugs Tiragolumab and Atezolizumab to Improve Outcomes for Patients With Recurrent Glioblastoma

Phase 2
Withdrawn
Conditions
Recurrent Glioblastoma, IDH-Wildtype
Interventions
Biological: Atezolizumab
Procedure: Biospecimen Collection
Procedure: Magnetic Resonance Imaging
Procedure: Surgical Procedure
Biological: Tiragolumab
First Posted Date
2024-03-25
Last Posted Date
2024-12-30
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
52
Registration Number
NCT06328036

A Rollover Study for Participants Previously Enrolled in a Genentech and/or F. Hoffman-La Roche Sponsored Study

Phase 3
Recruiting
Conditions
Cancer
Interventions
First Posted Date
2023-05-17
Last Posted Date
2025-01-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
60
Registration Number
NCT05862285
Locations
🇧🇪

GHdC Site Notre Dame, Charleroi, Belgium

🇫🇷

Institut de Cancérologie de Bourgogne, Dijon, France

🇫🇷

Centre Régional de Lutte Contre Le Cancer Val D'aurelle Paul Lamarque, Montpellier, France

and more 21 locations

An Umbrella Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Gastric or Gastroesophageal Junction Carcinoma

Phase 1
Active, not recruiting
Conditions
Gastric and Gastroesophageal Junction Carcinoma
Interventions
First Posted Date
2022-02-23
Last Posted Date
2025-01-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
40
Registration Number
NCT05251948
Locations
🇨🇳

the First Hospital of Jilin University, Changchun, China

🇨🇳

First Affiliated Hospital of Gannan Medical University, Ganzhou, China

🇨🇳

Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China

and more 7 locations

Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatments and Combinations in Patients With Urothelial Carcinoma (MORPHEUS-UC)

First Posted Date
2019-03-11
Last Posted Date
2025-01-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
272
Registration Number
NCT03869190
Locations
🇫🇷

Centre Francois Baclesse, Caen, France

🇬🇷

Attiko Hospital University of Athens, Athens, Greece

🇬🇷

Athens Medical Center, Athens, Greece

and more 30 locations
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