Interventional, Monocentric, Double-blind Randomized Category 2b Study Evaluating the Evaluation of the Tolerance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post -Inflammatory Hyperpigmentation (Pih)) on the Face
Not Applicable
Completed
- Conditions
- LentigoSolar LentigoPost Inflammatory Hyperpigmentation
- Interventions
- Device: CRYONOVE (EC14_4osc)Device: CRYONOVE (EC05osc)
- First Posted Date
- 2024-04-11
- Last Posted Date
- 2024-12-24
- Lead Sponsor
- Cryonove Pharma
- Target Recruit Count
- 30
- Registration Number
- NCT06361251
- Locations
- πΏπ¦
SMU - Photobiology Laboratory, Sefako Makgatho Health Sciences University, Pretoria, South Africa
Evaluation of the Tolerance (Main Objective) and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post-inflammatory Hyperpigmentation) on the Face
Not Applicable
Not yet recruiting
- Conditions
- Solar LentigoLentigoPost Inflammatory Hyperpigmentation
- Interventions
- Device: CRYONOVE (EC14_4osc)Device: CRYONOVE (EC+05_1osc)Device: CRYONOVE (EC+05_2osc)
- First Posted Date
- 2024-03-12
- Last Posted Date
- 2024-04-17
- Lead Sponsor
- Cryonove Pharma
- Target Recruit Count
- 45
- Registration Number
- NCT06305897
Performance and Tolerance of Cyto-selective Difluoroethane-based Cryotherapy in th Treatment of Brown Spots (Solar and Senile Lentigines, Post-Inflammatory Hyperpigmentation) on the Face and Hands of Asian Ethnicity Skins
Not Applicable
Not yet recruiting
- Conditions
- Solar LentigoSenile Lentigo
- Interventions
- Device: prototypes 1 everydayDevice: prototypes 2 every two weeksDevice: prototypes 1 every weekDevice: prototypes 3 every two weeksDevice: prototypes 1 every two weeks
- First Posted Date
- 2023-06-02
- Last Posted Date
- 2023-06-02
- Lead Sponsor
- Cryonove Pharma
- Target Recruit Count
- 120
- Registration Number
- NCT05886010
- Locations
- π«π·
Laboratoire BIO-EC, Longjumeau, France
Tolerance and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post-Inflammatory Hyperpigmentation)
Not Applicable
Not yet recruiting
- Conditions
- Solar LentigoPost Inflammatory HyperpigmentationSenile Lentigo
- First Posted Date
- 2023-06-01
- Last Posted Date
- 2023-06-01
- Lead Sponsor
- Cryonove Pharma
- Target Recruit Count
- 80
- Registration Number
- NCT05883657
- Locations
- πΏπ¦
Photobiology Laboratory, Sefako Makgatho Health Sciences University, Pretoria, Gauteng, South Africa
Tolerance and Performance (Mode of Administration) of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots
Not Applicable
Completed
- Conditions
- Lentigo SolarSenile Lentigo
- Interventions
- Device: Prototypes (816-v1 301) to (816-v1 355) every two weeksDevice: Prototypes (816-v1 301) to (816-v1 355) every week
- First Posted Date
- 2023-03-31
- Last Posted Date
- 2023-11-03
- Lead Sponsor
- Cryonove Pharma
- Target Recruit Count
- 20
- Registration Number
- NCT05793619
- Locations
- π¬πͺ
Ltd "Health", Batumi, Georgia
Tolerance and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots.
Not Applicable
Completed
- Conditions
- Solar LentigoPost-inflammatory HyperpigmentationSenile Lentigo
- Interventions
- Device: Prototype (816-v1 051) to (816-v1 100)Device: Prototypes (816-v1 001) to (816-v1 050)Device: Prototypes (816-v1 151) to (816-v1 200)Device: Prototypes (816-v1 101) to (816-v1 150)
- First Posted Date
- 2022-11-23
- Last Posted Date
- 2024-01-19
- Lead Sponsor
- Cryonove Pharma
- Target Recruit Count
- 32
- Registration Number
- NCT05625815
- Locations
- πΏπ¦
SMU - Photobiology Laboratory, Sefako Makgatho Health Sciences University, Pretoria, South Africa
Tolerance and Performance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots
Not Applicable
Completed
- Conditions
- Lentigo Solar
- Interventions
- Device: Prototype (815-v1 051) to (815-v1 100)Device: Prototypes (815-v1 001) to (815-v1 050)Device: Prototypes (815-v1 151) to (815-v1 200)Device: Prototypes (815-v1 101) to (815-v1 150)
- First Posted Date
- 2022-10-31
- Last Posted Date
- 2023-06-15
- Lead Sponsor
- Cryonove Pharma
- Target Recruit Count
- 33
- Registration Number
- NCT05600049
- Locations
- π¬πͺ
Ltd "Health", Batumi, Georgia
Tolerance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Post-inflamamatory Hyperpigmentation (PIH).
Not Applicable
Completed
- Conditions
- Post-inflammatory Hyperpigmentation
- Interventions
- Device: Prototype (814C-v1)Device: Prototype (814B-v1)Device: Prototype (814A-v1)Device: Prototype (814D-v1)
- First Posted Date
- 2022-08-10
- Last Posted Date
- 2023-06-26
- Lead Sponsor
- Cryonove Pharma
- Target Recruit Count
- 12
- Registration Number
- NCT05495503
- Locations
- πΏπ¦
Photobiology Laboratory, Sefako Makgatho Health Sciences University, Pretoria, Gauteng, South Africa
Tolerance of Cyto-selective Difluoroethane-based Cryotherapy
Not Applicable
Completed
- Conditions
- Solar Lentigo
- Interventions
- Device: Prototypes (812A-v1), (812C-v1), (812D-v1) and (812F-v1)
- First Posted Date
- 2022-04-12
- Last Posted Date
- 2022-08-19
- Lead Sponsor
- Cryonove Pharma
- Target Recruit Count
- 3
- Registration Number
- NCT05322668
- Locations
- πΊπ¦
VIDNOVLENNYA medical center, Zhytomyr, Ukraine
Tolerance and Mode of Administration of Cyto-selective Cryotherapy Treatments in Face Brown Spots: Proof of Concept
Not Applicable
Completed
- Conditions
- Solar Lentigo
- Interventions
- Device: (810A-v1) device prototypeDevice: (810C-v1) device prototypeDevice: (810B-v1) device prototype
- First Posted Date
- 2022-01-24
- Last Posted Date
- 2022-08-19
- Lead Sponsor
- Cryonove Pharma
- Target Recruit Count
- 23
- Registration Number
- NCT05203263
- Locations
- πΊπ¦
VIDNOVLENNYA medical center, Zhytomyr, Ukraine
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