MedPath

Septerna

🇺🇸United States
Ownership
-
Employees
68
Market Cap
-
Website
Introduction

Septerna, Inc. is a clinical-stage biotechnology company, which engages in pioneering a new era of G protein-coupled receptor oral small molecule drug discovery powered by proprietary Native Complex PlatformTM. Its pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic diseases. The company was founded by Robert Joseph Lefkowitz, Arthur Christopoulos, Patrick Sexton, and Jeffrey T. Finer in December 2019 and is headquartered in South San Francisco, CA.

Clinical Trials

5

Active:0
Completed:2

Trial Phases

1 Phases

Not Applicable:1

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (1 trials with phase data)• Click on a phase to view related trials

Not Applicable
1 (100.0%)

Oral Care Study on Burn Patients

Withdrawn
Conditions
Burn
First Posted Date
2011-02-24
Last Posted Date
2016-10-13
Lead Sponsor
Saint Elizabeth Regional Medical Center
Registration Number
NCT01302457
Locations
🇺🇸

Saint Elizabeth Regional Medical Center, Lincoln, Nebraska, United States

Effect of Cranberry Extract on Infections in Burn Patients

Not Applicable
Withdrawn
Conditions
Burn
Interventions
Dietary Supplement: Cranberry Extract
Drug: Inert Placebo Capsule
First Posted Date
2010-10-20
Last Posted Date
2016-10-13
Lead Sponsor
Saint Elizabeth Regional Medical Center
Registration Number
NCT01225107
Locations
🇺🇸

Saint Elizabeth Regional Medical Center, Lincoln, Nebraska, United States

Efficiency and Efficacy of the Distress Thermometer in the Burn and Wound Population (Research Mentoring High Student Project)

Completed
Conditions
Burns
First Posted Date
2010-07-26
Last Posted Date
2010-07-26
Lead Sponsor
Saint Elizabeth Regional Medical Center
Registration Number
NCT01169285

A Prospective Study of Body Image, Social Avoidance and Distress and Psychological Functioning in Burn Patients

Withdrawn
Conditions
Depression
Anxiety
Body Image
First Posted Date
2010-06-03
Last Posted Date
2016-10-13
Lead Sponsor
Saint Elizabeth Regional Medical Center
Registration Number
NCT01136070
Locations
🇺🇸

Saint Elizabeth Regional Medical Center, Lincoln, Nebraska, United States

Cesarean Postoperative Pain Satisfaction

Completed
Conditions
Cesarean
First Posted Date
2009-06-17
Last Posted Date
2011-07-20
Lead Sponsor
Saint Elizabeth Regional Medical Center
Target Recruit Count
120
Registration Number
NCT00922142
Locations
🇺🇸

Saint Elizabeth Regional Medical Center, Lincoln, Nebraska, United States

News

Novo Nordisk and Septerna Partner on $2.2 Billion Deal to Develop Oral Obesity Treatments

Novo Nordisk and Septerna have formed a $2.2 billion collaboration to develop oral small molecule therapies targeting GLP-1, GIP, and glucagon receptors for obesity and cardiometabolic diseases.

Novo Nordisk Invests $2 Billion in Chinese "Triple G" Weight Loss Treatment

Novo Nordisk has committed $2 billion to develop a novel "triple G" weight loss injection in China, expanding its portfolio beyond its successful GLP-1 medications Ozempic and Wegovy.

Septerna Halts Phase 1 Trial of SEP-786 for Hypoparathyroidism Due to Safety Concerns

Septerna discontinues Phase 1 trial of SEP-786, an oral PTH1R agonist for hypoparathyroidism, following two cases of severe elevated unconjugated bilirubin in multiple-ascending dose study.

Septerna Raises $288M in Upsized IPO to Advance Novel GPCR-Targeting Drug Pipeline

• Septerna successfully completed an upsized IPO raising $288 million, selling 16 million shares at $18 each, demonstrating strong investor confidence in clinical-stage biotech companies. • The company's lead drug candidate SEP-786, targeting hypoparathyroidism, recently entered Phase 1 clinical trials with data expected by mid-2025. • Septerna plans to allocate $117 million of the proceeds to advance SEP-786 and $37 million for developing SEP-631 for chronic spontaneous urticaria and mast cell conditions.

Septerna Initiates Phase 1 Trial of Oral PTH1R Agonist SEP-786 for Hypoparathyroidism

Septerna has commenced a Phase 1 clinical trial for SEP-786, a novel oral small molecule agonist targeting the parathyroid hormone 1 receptor (PTH1R).

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