SOUTH TEXAS VETERANS HEALTH CARE SYSTEM

Clinical Trials Advance for Potential Kennedy's Disease Therapies

6 months ago

• Structured exercise programs are under Phase 2 trials to improve muscle strength and function in Kennedy's disease patients. • Clenbuterol, an asthma drug, is in Phase 2 trials to assess its ability to enhance muscle stamina and quality of life. • AJ201, a curcumin-based drug, is undergoing Phase 1/2a trials to evaluate safety and its potential to break down faulty androgen receptor protein. • Leuprorelin acetate, originally for prostate cancer, is in Phase 3 trials to determine its long-term efficacy and safety in slowing Kennedy's disease progression.

Semaglutide Investigated for Diabetes, Obesity in Spinal Cord Injury Patients

9 months ago

• A clinical trial is underway to investigate the mechanisms behind diabetes and obesity in individuals with spinal cord injuries. • The study will assess the safety and efficacy of semaglutide, a GLP-1 receptor agonist, in treating these metabolic conditions in this population. • Researchers aim to understand how semaglutide impacts glucose tolerance, insulin action, and body composition in patients with spinal cord injury. • The trial seeks to address the lack of research and treatment guidelines for diabetes and obesity in this high-risk population.