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🇺🇸United States

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Clinical Trials

Study of Pelvic Hypofractionated Radiotherapy in Endometrial Cancer

Phase 1

Recruiting

Conditions: Endometrial Cancer

Interventions: Radiation: Hypofractionated Radiation
Other: Clinical Follow-Up and Assessments

First Posted Date: 2020-12-24

Last Posted Date: 2024-10-14

Lead Sponsor: University of Chicago

Target Recruit Count: 100

Registration Number: NCT04683653

Locations: 🇺🇸
University of Illinois at Chicago (UIC), Chicago, Illinois, United States
🇺🇸
MD Anderson Cancer Center, Houston, Texas, United States
🇺🇸
Huntsman Cancer Institute, Salt Lake City, Utah, United States

and more 1 locations

Telotristat Ethyl for Reducing Intraoperative Carcinoid Crisis in Patients With Neuroendocrine Tumors

Phase 2

Withdrawn

Conditions: Neuroendocrine Tumors

Interventions: Drug: Telotristat Ethyl Oral Tablet

First Posted Date: 2020-12-17

Last Posted Date: 2021-12-17

Lead Sponsor: University of Chicago

Registration Number: NCT04672876

Drugs Brain and Behavior (DDP)

Early Phase 1

Completed

Conditions: Stimulant Use

Interventions: Drug: Methamphetamine
Drug: placebo oral tablet

First Posted Date: 2020-11-24

Last Posted Date: 2024-08-19

Lead Sponsor: University of Chicago

Target Recruit Count: 113

Registration Number: NCT04642820

Locations: 🇺🇸
University of Chicago, Chicago, Illinois, United States

Gut Microbiome and Sex as Risk Factors for Kidney Stones After Bariatric Surgery

Not Applicable

Recruiting

Conditions: Bariatric Surgery Candidate

Interventions: Other: Special diet

First Posted Date: 2020-10-19

Last Posted Date: 2024-05-24

Lead Sponsor: University of Chicago

Target Recruit Count: 28

Registration Number: NCT04590690

Locations: 🇺🇸
University of Chicago Medical Center, Chicago, Illinois, United States

Genicular Artery Embolization to Reduce Pain Associated With Unilateral Mild to Moderate Osteoarthritis

Not Applicable

Completed

Conditions: Knee Osteoarthritis

Interventions: Device: the Terumo Hydropearl® microspheres device

First Posted Date: 2020-10-19

Last Posted Date: 2024-11-04

Lead Sponsor: University of Chicago

Target Recruit Count: 5

Registration Number: NCT04592562

Locations: 🇺🇸
University of Chicago Hospital, Chicago, Illinois, United States

Pilot Study of Chemotherapy for HPV-Associated Oropharyngeal Cancer

Phase 1

Completed

Conditions: Oropharyngeal Squamous Cell Carcinoma

Interventions: Other: Transoral Robotic Surgery (TORS) or Radiotherapy
Other: Chemotherapy and Low-Dose Radiotherapy
Other: Chemotherapy and High-Dose Radiotherapy
Drug: Paclitaxel
Drug: Carboplatin

First Posted Date: 2020-10-01

Last Posted Date: 2023-07-07

Lead Sponsor: University of Chicago

Target Recruit Count: 50

Registration Number: NCT04572100

Locations: 🇺🇸
University of Chicago Medical Center, Chicago, Illinois, United States

Alterations of the Microbiome During Critical Illness With Short and Long Term Clinical Outcomes

Active, not recruiting

Conditions: Critical Illness
Microbiome

First Posted Date: 2020-09-17

Last Posted Date: 2024-12-09

Lead Sponsor: University of Chicago

Target Recruit Count: 500

Registration Number: NCT04552834

Locations: 🇺🇸
University of Chicago Medical Center, Chicago, Illinois, United States

The PhOCus Trial: Implementation of Pharmacogenomic Testing in Oncology Care

Not Applicable

Recruiting

Conditions: Gastrointestinal Cancer
UGT1A1 Gene Mutation
Head and Neck Cancer
Dihydropyrimidine Dehydrogenase Deficiency
Breast Cancer

Interventions: Other: Availability of clinical decision support based on pharmacogenomic results.

First Posted Date: 2020-09-09

Last Posted Date: 2024-01-29

Lead Sponsor: University of Chicago

Target Recruit Count: 860

Registration Number: NCT04541381

Locations: 🇺🇸
University of Chicago Medical Center, Chicago, Illinois, United States

Olaparib in Patients With HRD Malignant Mesothelioma

Phase 2

Recruiting

Conditions: Mesothelioma
Homologous Recombination Deficiency

Interventions: Drug: Olaparib

First Posted Date: 2020-08-17

Last Posted Date: 2024-10-23

Lead Sponsor: University of Chicago

Target Recruit Count: 56

Registration Number: NCT04515836

Locations: 🇺🇸
University of Chicago Medical Center, Chicago, Illinois, United States

Implementing a Multilevel Intervention to Accelerate Colorectal Cancer Screening and Follow-up

Completed

Conditions: Colorectal Cancer

First Posted Date: 2020-08-14

Last Posted Date: 2024-12-13

Lead Sponsor: Milton S. Hershey Medical Center

Target Recruit Count: 74560

Registration Number: NCT04514341

Locations: 🇺🇸
PCC Community Wellness Centers, Oak Park, Illinois, United States

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