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PFIZER INC.

🇺🇸United States

Country: 🇺🇸United States

Ownership: Public

Established: 1849-01-01

Employees: 88K

Market Cap: $163.3B

Website: http://www.pfizer.com

Clinical Trials

Safety and Efficacy of Benefix in Patients With Hemophilia B in Usual Care Settings in China

Phase 4

Completed

Conditions: HEMOPHILIA B

Interventions: Drug: Benefix

First Posted Date: 2015-01-12

Last Posted Date: 2017-05-04

Lead Sponsor: Pfizer

Target Recruit Count: 70

Registration Number: NCT02336178

Locations: 🇨🇳
Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China
🇨🇳
The Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China
🇨🇳
Henan Provincial People's Hospital, Zhengzhou, Henan, China

and more 13 locations

A Study To Describe The Effect Of Impaired Hepatic Function Of The Pharmacokinetics Of Palbociclib

Phase 1

Completed

Conditions: Healthy, Hepatic Insufficiency

Interventions: Drug: Palbociclib 75 mg Capsule

First Posted Date: 2015-01-08

Last Posted Date: 2018-01-24

Lead Sponsor: Pfizer

Target Recruit Count: 28

Registration Number: NCT02334800

Locations: 🇺🇸
Orlando Clinical Research Center, Orlando, Florida, United States
🇺🇸
Weston Diagnostics (Ultrasound Facility), Orlando, Florida, United States

Safety and Efficacy Study of Enzalutamide Plus Leuprolide in Patients With Nonmetastatic Prostate Cancer (EMBARK)

Phase 3

Active, not recruiting

Conditions: Hormone Sensitive Prostate Cancer
Prostate Cancer
Cancer of the Prostate

Interventions: Drug: Enzalutamide
Drug: Placebo (No longer applicable in Open Label study period)
Drug: Leuprolide Open Label

First Posted Date: 2014-12-18

Last Posted Date: 2025-02-27

Lead Sponsor: Pfizer

Target Recruit Count: 1068

Registration Number: NCT02319837

Locations: 🇸🇰
MILAB, Presov, Slovakia
🇺🇸
Emory University Hospital, Atlanta, Georgia, United States
🇺🇸
Winship Cancer Institute, Emory University, Atlanta, Georgia, United States

and more 240 locations

A Study to Estimate the Effect of CYP3A4 Inhibitors (Itraconazole, Diltiazem or Verapamil) on the Pharmacokinetics of Single Dose PF- 00489791 in Healthy Volunteers

Phase 1

Completed

Conditions: Healthy Volunteers

Interventions: Drug: itraconazole
Drug: SR verapamil
Drug: diltiazem
Drug: PF-00489791

First Posted Date: 2014-12-18

Last Posted Date: 2016-09-16

Lead Sponsor: Pfizer

Target Recruit Count: 22

Registration Number: NCT02319148

Locations: 🇧🇪
Pfizer Clinical Research Unit, Brussels, Belgium

A Single Ascending Dose Study To Evaluate Safety And Pharmacokinetics Of Compound PF-06648671 In Healthy Subjects

Phase 1

Completed

Conditions: Healthy Subjects

Interventions: Drug: PF-06648671
Drug: Placebo

First Posted Date: 2014-12-15

Last Posted Date: 2015-06-09

Lead Sponsor: Pfizer

Target Recruit Count: 18

Registration Number: NCT02316756

Locations: 🇧🇪
Pfizer Clinical Research Unit, Brussels, Belgium

Observational Study Evaluating The Efficacy And Effects On Quality Of Life Of Targeted Treatments Following TKIs In mRCC

Completed

Conditions: Renal Cell Carcinoma

First Posted Date: 2014-12-12

Last Posted Date: 2019-07-26

Lead Sponsor: Pfizer

Target Recruit Count: 102

Registration Number: NCT02315755

Locations: 🇹🇷
Gazi University, Ankara, Besevler, Turkey
🇹🇷
Trakya Universitesi Tip Fakultesi Ic Hastaliklari Anabilim Dali Tibbi Onkoloji Bilim Dal, Edirne, Turkey
🇹🇷
Abdurrahman Yurtaslan Onkoloji Hastanesi, Ankara, Demetevler, Turkey

and more 16 locations

Study Of OX40 Agonist PF-04518600 Alone And In Combination With 4-1BB Agonist PF-05082566

Phase 1

Completed

Conditions: Neoplasms

Interventions: Drug: PF-04518600 plus PF-05082566
Drug: PF-04518600

First Posted Date: 2014-12-11

Last Posted Date: 2022-04-21

Lead Sponsor: Pfizer

Target Recruit Count: 174

Registration Number: NCT02315066

Locations: 🇺🇸
The Angeles Clinic And Research Institute, A Cedars-Sinai Affiliate, Los Angeles, California, United States
🇺🇸
LAC+USC Medical Center, Los Angeles, California, United States
🇺🇸
Beth Israel Deaconess Medical Center (BIDMC), Boston, Massachusetts, United States

and more 27 locations

A Pilot Study To Investigate The Effect Of Concurrent Antacid Administration On The Bioavailability Of Six Experimental Formulations Of Palbociclib

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: Palbociclib Alone
Drug: Palbociclib + Rabeprazole

First Posted Date: 2014-12-09

Last Posted Date: 2015-05-28

Lead Sponsor: Pfizer

Target Recruit Count: 60

Registration Number: NCT02311946

Locations: 🇺🇸
MRA Clinical Research - Phase 1, Miami, Florida, United States
🇺🇸
Miami Research Associates, LLC, South Miami, Florida, United States
🇺🇸
MRA Clinical Research, LLC, South Miami, Florida, United States

Expanded Access /Compassionate Use Protocol For Relapsed Or Refractory CD33 Positive AML Patients In The USA Without Access To Comparable Or Alternative Therapy

Conditions: CD33 Positive Acute Myelogenous Leukemia

First Posted Date: 2014-12-09

Last Posted Date: 2019-08-20

Lead Sponsor: Pfizer

Registration Number: NCT02312037

Locations: 🇺🇸
Kaiser Permanente - Santa Clara, Santa Clara, California, United States
🇺🇸
Kaiser Permanente - Oakland Medical Center, Oakland, California, United States
🇺🇸
Kaiser Permanente - Roseville, Roseville, California, United States

and more 132 locations

A Phase 2 Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of PF-06252616 in Duchenne Muscular Dystrophy

Phase 2

Terminated

Conditions: Duchenne Muscular Dystrophy

Interventions: Biological: PF-06252616
Drug: Placebo

First Posted Date: 2014-12-08

Last Posted Date: 2020-12-07

Lead Sponsor: Pfizer

Target Recruit Count: 121

Registration Number: NCT02310763

Locations: 🇺🇸
Shriners Hospitals for Children - Tampa, Tampa, Florida, United States
🇺🇸
University of Iowa ICTS, Iowa City, Iowa, United States
🇺🇸
St Louis Children's Hospital, Saint Louis, Missouri, United States

and more 62 locations

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