PFIZER INC.

🇺🇸United States

Country: 🇺🇸United States

Ownership: Public

Established: 1849-01-01

Employees: 88K

Market Cap: $163.3B

Website: http://www.pfizer.com

Clinical Trials

A Study of HR+/HER2- Metastatic Breast Cancer Patients Treated With Palbociclib Together With an Aromatase Inhibitor From 2017 to 2023 in Denmark.

Completed

Conditions: Breast Cancer

Interventions: Drug: Palbociclib in combination with AI

First Posted Date: 2024-03-12

Last Posted Date: 2024-05-02

Lead Sponsor: Pfizer

Target Recruit Count: 1

Registration Number: NCT06307457

Locations: 🇩🇰
Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark

A Study to Learn About the Study Medicine Bosulif in Adult Patients With Chronic Myeloid Leukemia(CML).

Not yet recruiting

Conditions: Chronic Leukemia Myelogenous

Interventions: Drug: Bosulif

First Posted Date: 2024-03-07

Last Posted Date: 2024-07-26

Lead Sponsor: Pfizer

Target Recruit Count: 600

Registration Number: NCT06297161

A Study to Learn About the Effectiveness of Etrasimod in People With Ulcerative Colitis

Recruiting

Conditions: Colitis, Ulcerative

Interventions: Drug: Etrasimod

First Posted Date: 2024-03-06

Last Posted Date: 2024-12-20

Lead Sponsor: Pfizer

Target Recruit Count: 260

Registration Number: NCT06294925

Locations: 🇩🇪
Praxis Heil und Müller, Andernach, Germany
🇬🇧
Imperial College Healthcare NHS, London, United Kingdom
🇬🇧
University College London Hospital, London, United Kingdom

and more 26 locations

A Study to Learn About the Use of Paxlovid in Patients With COVID-19 in the Kingdom of Bahrain.

Completed

Conditions: COVID-19

Interventions: Other: Controls
Drug: nirmatrelvir, ritonavir

First Posted Date: 2024-03-04

Last Posted Date: 2024-06-04

Lead Sponsor: Pfizer

Target Recruit Count: 3000

Registration Number: NCT06291831

Locations: 🇧🇭
Pfizer Gulf FZ, Busaiteen, Bahrain

A Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors

Phase 1

Terminated

Conditions: Melanoma
Urothelial Carcinoma
Colorectal Carcinoma
Neoplasms
Non-small-cell Lung Cancer
Squamous Cell Carcinoma of the Head and Neck
Renal Cell Carcinoma
Ovarian Carcinoma

Interventions: Drug: PF-07820435
Biological: Sasanlimab

First Posted Date: 2024-02-29

Last Posted Date: 2025-03-13

Lead Sponsor: Pfizer

Target Recruit Count: 9

Registration Number: NCT06285097

Locations: 🇺🇸
Florida Cancer Specialists Sarasota Drug Development Unit, Sarasota, Florida, United States
🇺🇸
Corewell Health (reference non-engagement letter), Grand Rapids, Michigan, United States
🇺🇸
START Midwest, Grand Rapids, Michigan, United States

and more 7 locations

Litfulo Capsules Special Investigation

Active, not recruiting

Conditions: Alopecia Areata

Interventions: Drug: LITFULO

First Posted Date: 2024-02-28

Last Posted Date: 2025-03-13

Lead Sponsor: Pfizer

Target Recruit Count: 191

Registration Number: NCT06279221

Locations: 🇯🇵
Pfizer, Tokyo, Japan

A Study to Learn How Different Amounts of PF-06954522 Are Tolerated and Act in Adults With Type 2 Diabetes Mellitus

Phase 1

Completed

Conditions: Type 2 Diabetes Mellitus (T2DM)
Obesity

Interventions: Drug: Rosuvastatin
Drug: Placebo
Drug: Midazolam
Drug: Omeprazole
Drug: PF-06954522

First Posted Date: 2024-02-28

Last Posted Date: 2025-06-03

Lead Sponsor: Pfizer

Target Recruit Count: 50

Registration Number: NCT06279234

Locations: 🇺🇸
Anaheim Clinical Trials, LLC, Anaheim, California, United States
🇺🇸
Qps-Mra, Llc, South Miami, Florida, United States

A Study to Learn About Lorlatinib in Patients With Non-Small Cell Lung Cancer Which Could Not Be Controlled

Completed

Conditions: Non-Small Cell Lung Carcinoma

Interventions: Drug: Lorlatinib

First Posted Date: 2024-02-28

Last Posted Date: 2024-02-28

Lead Sponsor: Pfizer

Target Recruit Count: 73

Registration Number: NCT06282991

Locations: 🇨🇳
Taichung Veterans General Hospital, Taichung, Taiwan
🇨🇳
Taipei Veterans General Hospital, Taipei, Taiwan
🇨🇳
CHANG GUNG MEMORIAL HOSPITAL Kaohsiung Branch, Kaohsiung City, Taiwan

and more 3 locations

A Study to Learn How Different Forms of Study Medicine Tafamidis Are Taken Up Into The Blood in Healthy Adults

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: Tafamidis 61 mg free acid tablet (Test 1)
Drug: Tafamidis 70 mg free acid tablet (Test 1)
Drug: Tafamidis 61 mg free acid capsule (Reference)

First Posted Date: 2024-02-23

Last Posted Date: 2024-06-26

Lead Sponsor: Pfizer

Target Recruit Count: 12

Registration Number: NCT06273839

Locations: 🇧🇪
Pfizer Clinical Research Unit - Brussels, Brussels, Bruxelles-capitale, Région DE, Belgium

A Study to Learn If the Study Medicine Esomeprazole Changes How the Body Processes the Other Study Medicine Vepdegestrant

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: vepdegestrant
Drug: esomeprazole

First Posted Date: 2024-02-23

Last Posted Date: 2024-06-03

Lead Sponsor: Pfizer

Target Recruit Count: 12

Registration Number: NCT06275841

Locations: 🇺🇸
Pfizer Clinical Research Unit - New Haven, New Haven, Connecticut, United States

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