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PFIZER INC.

PFIZER INC. logo
🇺🇸United States
Ownership
Public
Established
1849-01-01
Employees
88K
Market Cap
$163.3B
Website
http://www.pfizer.com

Study of the Combination of Binimetinib and Encorafenib in Adolescent Patients With Unresectable or Metastatic BRAF V600-mutant Melanoma

Phase 1
Terminated
Conditions
Melanoma
Interventions
First Posted Date
2019-03-18
Last Posted Date
2023-04-03
Lead Sponsor
Pfizer
Target Recruit Count
1
Registration Number
NCT03878719
Locations
🇮🇹

Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Lombardy, Italy

Acute Treatment Trial in Adult Subjects With Migraines

Phase 2
Completed
Conditions
Migraine
Interventions
Drug: Zavegepant
Drug: Zavegepant matching placebo
Device: Intranasal Aptar Pharma Unit Dose System
First Posted Date
2019-03-13
Last Posted Date
2023-09-25
Lead Sponsor
Pfizer
Target Recruit Count
2154
Registration Number
NCT03872453
Locations
🇺🇸

CT Clinical Research, Cromwell, Connecticut, United States

🇺🇸

Elite Clinical Studies, Phoenix, Arizona, United States

🇺🇸

Optimus Medical Group, San Francisco, California, United States

and more 72 locations

OPEN LABEL, 2-PERIOD STUDY, TO COMPARE BIO-AVAILABILITY OF 2 DIFFERENT FORMULATIONS OF PF-05221304 IN HEALTHY ADULTS

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: PF-05221304 Formulation B
Drug: PF-05221304 Formulation A
First Posted Date
2019-03-12
Last Posted Date
2020-05-20
Lead Sponsor
Pfizer
Target Recruit Count
10
Registration Number
NCT03871439
Locations
🇺🇸

Pfizer New Haven Clinical Research Unit, New Haven, Connecticut, United States

Pharmacokinetic Drug-drug Interaction Study of Encorafenib and Binimetinib on Probe Drugs in Patients With BRAF V600-mutant Melanoma or Other Advanced Solid Tumors

First Posted Date
2019-03-06
Last Posted Date
2023-06-08
Lead Sponsor
Pfizer
Target Recruit Count
56
Registration Number
NCT03864042
Locations
🇨🇦

Sir Mortimer B Davis Jewish General Hospital, Montreal, Quebec, Canada

🇺🇸

UC Irvine Health, Orange, California, United States

🇺🇸

University of Colorado Hospital - Anschutz Cancer Pavilion (ACP), Aurora, Colorado, United States

and more 26 locations

Evaluate Severe Hepatic Impairment on Dacomitinib PK

Phase 1
Completed
Conditions
Severe Hepatic Impairment
Interventions
First Posted Date
2019-03-06
Last Posted Date
2020-11-06
Lead Sponsor
Pfizer
Target Recruit Count
16
Registration Number
NCT03865446
Locations
🇺🇸

Investigational Drug Services (IDS) University of Miami Hospitals and Clinics, Research Pharmacy, Miami, Florida, United States

🇺🇸

University of Miami Division of Clinical Pharmacology, Miami, Florida, United States

🇺🇸

Orlando Clinical Research Center, Orlando, Florida, United States

Study Evaluating the Effects of PSI-697 on Platelets in Subjects Who Smoke

Phase 1
Completed
Conditions
Healthy
Interventions
Drug: PSI-697
Drug: Placebo
First Posted Date
2019-03-04
Last Posted Date
2019-03-04
Lead Sponsor
Pfizer
Target Recruit Count
30
Registration Number
NCT03860506

A Study to Evaluate the Efficacy and Safety of Factor IX Gene Therapy With PF-06838435 in Adult Males With Moderately Severe to Severe Hemophilia B

Phase 3
Active, not recruiting
Conditions
Hemophilia B
Interventions
Biological: PF-06838435/ fidanacogene elaparvovec
First Posted Date
2019-03-04
Last Posted Date
2024-12-03
Lead Sponsor
Pfizer
Target Recruit Count
51
Registration Number
NCT03861273
Locations
🇸🇦

King Abdulaziz Medical City-Ministry of national guard, Riyadh, Kingdom OF Saudi Arabia, Saudi Arabia

🇺🇸

University of California, San Francisco - Clinical Research Center, San Francisco, California, United States

🇺🇸

University of California, San Francisco - Outpatient Hematology Clinic, San Francisco, California, United States

and more 60 locations

A Dose Escalation Study Of PF-06939999 In Participants With Advanced Or Metastatic Solid Tumors

Phase 1
Terminated
Conditions
Metastatic Solid Tumors
Advanced Solid Tumors
Interventions
Drug: PF-06939999 dose escalation
Drug: PF-06939999 monotherapy
Drug: PF-06939999 in combination with docetaxel
First Posted Date
2019-02-26
Last Posted Date
2022-11-22
Lead Sponsor
Pfizer
Target Recruit Count
54
Registration Number
NCT03854227
Locations
🇺🇸

Scottsdale Healthcare Hospitals d/b/a HonorHealth, Scottsdale, Arizona, United States

🇺🇸

Virginia G. Piper Cancer Pharmacy, Scottsdale, Arizona, United States

🇺🇸

Keck Hospital of USC, Los Angeles, California, United States

and more 19 locations

Dose Ranging Study To Assess Efficacy, Safety and Tolerability Of PF-06700841 Topical Cream In Psoriasis

Phase 2
Completed
Conditions
Psoriasis
Interventions
Drug: Vehicle (Placebo)
Drug: PF-06700841
First Posted Date
2019-02-21
Last Posted Date
2022-06-29
Lead Sponsor
Pfizer
Target Recruit Count
344
Registration Number
NCT03850483
Locations
🇯🇵

Tanpopo Skin Clinic, Ota Ku, Tokyo, Japan

🇱🇻

Aesthetic dermatology clinic of Prof. J. Kisis, Riga, Latvia

🇱🇻

Health and Aesthetics Ltd, Riga, Latvia

and more 74 locations

A DOSE-RANGING STUDY TO EVALUATE EFFICACY AND SAFETY OF PF-06700841 IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

Phase 2
Completed
Conditions
Systemic Lupus Erythematosus
Interventions
First Posted Date
2019-02-19
Last Posted Date
2023-11-01
Lead Sponsor
Pfizer
Target Recruit Count
350
Registration Number
NCT03845517
Locations
🇺🇸

Stamford Therapeutics Consortium, Stamford, Connecticut, United States

🇺🇸

Institute of Arthritis Research, Idaho Falls, Idaho, United States

🇺🇸

Northshore University Hospital, Manhasset, New York, United States

and more 154 locations
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