PFIZER INC.

🇺🇸United States

Country: 🇺🇸United States

Ownership: Public

Established: 1849-01-01

Employees: 88K

Market Cap: $163.3B

Website: http://www.pfizer.com

Clinical Trials

An Open-label Study of Encorafenib + Binimetinib in Patients With BRAFV600-mutant Non-small Cell Lung Cancer

Phase 2

Active, not recruiting

Conditions: Non-small Cell Lung Cancer

Interventions: Drug: encorafenib
Drug: binimetinib

First Posted Date: 2019-04-16

Last Posted Date: 2024-10-17

Lead Sponsor: Pfizer

Target Recruit Count: 98

Registration Number: NCT03915951

Locations: 🇺🇸
Ohio State CarePoint East, Columbus, Ohio, United States
🇺🇸
The Ohio State University James Cancer Hospital, Columbus, Ohio, United States
🇺🇸
Ohio State Eye and Ear Institute, Columbus, Ohio, United States

and more 114 locations

THE EFFECT OF MULTIPLE DOSES OF PF-06835919 ON THE PHARMACOKINETICS OF A SINGLE ORAL MIDAZOLAM DOSE IN HEALTHY PARTICIPANTS

Phase 1

Completed

Conditions: Healthy Volunteer

Interventions: Drug: PF 06835919
Drug: Midazolam

First Posted Date: 2019-04-16

Last Posted Date: 2019-07-16

Lead Sponsor: Pfizer

Target Recruit Count: 10

Registration Number: NCT03916406

Locations: 🇧🇪
Brussels Clinical Research Unit, Brussels, Be-bru, Belgium

PF-06651600 Taste Study.

Phase 1

Completed

Conditions: Healthy Participants

Interventions: Drug: PF-06651600 20 mg
Other: Bitrex solution

First Posted Date: 2019-04-16

Last Posted Date: 2019-06-05

Lead Sponsor: Pfizer

Target Recruit Count: 10

Registration Number: NCT03916393

Locations: 🇧🇪
Pfizer Clinical Research Unit, Brussels, Be-bru, Belgium

REGISTRY OF COMPLETE RESPONSES TO SUNITINIB IN SPANISH PATIENTS WITH METASTATIC RENAL CELL CARCINOMA

Completed

Conditions: Carcinoma, Renal Cell

First Posted Date: 2019-04-16

Last Posted Date: 2021-12-13

Lead Sponsor: Pfizer

Target Recruit Count: 62

Registration Number: NCT03916458

Locations: 🇪🇸
Hospital Duran i Reynals, Hospitalet de Llobregat, Barcelona, Spain
🇪🇸
Hospital Universitario Son Espases, Palma de Mallorca, Mallorca, Spain
🇪🇸
Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Tenerife, Spain

and more 28 locations

Study Evaluating the Mechanism of Action of PF-04965842 Monotherapy for Moderate-to-severe Atopic Dermatitis

Phase 2

Completed

Conditions: Atopic Dermatitis

Interventions: Drug: PF-04965842 200 mg
Drug: PF-04965842 100 mg
Drug: Placebo

First Posted Date: 2019-04-16

Last Posted Date: 2023-02-08

Lead Sponsor: Pfizer

Target Recruit Count: 46

Registration Number: NCT03915496

Locations: 🇺🇸
The Indiana Clinical Trials Center, PC - Dermatology Research, Plainfield, Indiana, United States
🇺🇸
Keck School of Medicine of USC - IDS Pharmacy, Los Angeles, California, United States
🇺🇸
ForCare Clinical Research, Tampa, Florida, United States

and more 8 locations

An Open-Label, Randomized, Multicenter Trial of Encorafenib + Binimetinib Evaluating a Standard-dose and a High-dose Regimen in Patients With BRAFV600-mutant Melanoma Brain Metastasis

Phase 2

Terminated

Conditions: Brain Metastases

Interventions: Drug: encorafenib
Drug: binimetinib

First Posted Date: 2019-04-11

Last Posted Date: 2023-05-31

Lead Sponsor: Pfizer

Target Recruit Count: 13

Registration Number: NCT03911869

Locations: 🇺🇸
UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, California, United States
🇺🇸
Rocky Mountain Lions Eye Institute (RMLEI), Aurora, Colorado, United States
🇦🇺
Crows Nest Eye Surgery, Crows Nest, New South Wales, Australia

and more 22 locations

A Study of Lorlatinib in ALK Inhibitor-Treated ALK-Positive NSCLC in China

Phase 2

Completed

Conditions: Carcinoma, Non-Small-Cell Lung

Interventions: Drug: Lorlatinib

First Posted Date: 2019-04-10

Last Posted Date: 2024-11-22

Lead Sponsor: Pfizer

Target Recruit Count: 109

Registration Number: NCT03909971

Locations: 🇨🇳
The first hospital of jilin university, Changchun, Jilin, China
🇨🇳
Tangdu Hospital of Fourth Military Medical University, Xi'an, Shanxi, China
🇨🇳
Sichuan Province Cancer Hospital/Department of Pulmonary Tumor, Chengdu, Sichuan, China

and more 18 locations

LORA-PITA IV General Investigation

Completed

Conditions: Status Epilepticus

Interventions: Drug: Lorazepam

First Posted Date: 2019-04-05

Last Posted Date: 2025-03-10

Lead Sponsor: Pfizer

Target Recruit Count: 206

Registration Number: NCT03905798

Locations: 🇯🇵
Pfizer Local Country office, Tokyo, Shibuya-ku, Japan

Dose Ranging Study to Assess Efficacy, Safety, Tolerability and Pharmacokinetics of PF-06700841 Topical Cream in Participants With Mild or Moderate Atopic Dermatitis

Phase 2

Completed

Conditions: Atopic Dermatitis

Interventions: Drug: PF-06700841
Drug: Vehicle (Placebo)

First Posted Date: 2019-04-04

Last Posted Date: 2021-03-29

Lead Sponsor: Pfizer

Target Recruit Count: 292

Registration Number: NCT03903822

Locations: 🇺🇸
Center for Dermatology and Plastic Surgery, Scottsdale, Arizona, United States
🇺🇸
First OC Dermatology, Fountain Valley, California, United States
🇺🇸
California Dermatology & Clinical Research Institute, Encinitas, California, United States

and more 70 locations

A Study to Evaluate Safety and Efficacy of PF-06826647 For Moderate To Severe Plaque Psoriasis

Phase 2

Completed

Conditions: Psoriasis

Interventions: Drug: PF-06826647 or Placebo
Drug: PF-06826647

First Posted Date: 2019-03-29

Last Posted Date: 2021-08-27

Lead Sponsor: Pfizer

Target Recruit Count: 179

Registration Number: NCT03895372

Locations: 🇺🇸
DelRicht Research, Baton Rouge, Louisiana, United States
🇨🇦
Centre Radiologique de l'Estrie, Sherbrooke, Quebec, Canada
🇨🇦
Diex Recherche Sherbrooke Inc., Sherbrooke, Quebec, Canada

and more 40 locations

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