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The Sidney Kimmel Comprehensive Cancer Center

🇺🇸United States
Ownership
Private, Subsidiary
Employees
-
Market Cap
-
Website
http://www.hopkinsmedicine.org/kimmel_cancer_center

Determining Dose of Regadenoson Most Likely to Transiently Alter the Integrity of the Blood-Brain Barrier in Patients With High Grade Gliomas

Phase 1
Terminated
Conditions
High Grade Glioma
Glioblastoma
Anaplastic Astrocytoma
Anaplastic Oligodendroglioma
Interventions
Drug: Regadensoson 0.1mg
Drug: Regadensoson 0.2mg
Drug: Regadensoson 0.4mg
Drug: Regadensoson 0.7mg
Drug: Regadensoson 1.0mg
Drug: Regadensoson 1.4mg
First Posted Date
2019-06-03
Last Posted Date
2023-10-06
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
7
Registration Number
NCT03971734
Locations
🇺🇸

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States

🇺🇸

Wake Forest University Comprehensive Cancer Center, Winston-Salem, North Carolina, United States

AXL Inhibitor BGB324 in Treating Participants With Recurrent Glioblastoma Undergoing Surgery

Early Phase 1
Terminated
Conditions
Brain and Central Nervous System Tumors
Interventions
Drug: BGB 324 (after surgery)
Drug: BGB 324 (before surgery)
First Posted Date
2019-05-29
Last Posted Date
2024-02-08
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
10
Registration Number
NCT03965494
Locations
🇺🇸

University of Pennsylvania, Philadelphia, Pennsylvania, United States

🇺🇸

Henry Ford Hospital, Detroit, Michigan, United States

🇺🇸

Comprehensive Cancer Center at University of Alabama at Birmingham, Birmingham, Alabama, United States

and more 3 locations

Trial of Anti-Tim-3 in Combination With Anti-PD-1 and SRS in Recurrent GBM

Phase 1
Active, not recruiting
Conditions
Glioblastoma Multiforme
Interventions
First Posted Date
2019-05-23
Last Posted Date
2025-01-03
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
16
Registration Number
NCT03961971
Locations
🇺🇸

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland, United States

🇺🇸

Stanford University, Stanford, California, United States

Neoadjuvant Immune Checkpoint Blockade in Resectable Malignant Pleural Mesothelioma

Phase 2
Active, not recruiting
Conditions
Mesothelioma
Interventions
First Posted Date
2019-04-17
Last Posted Date
2025-05-22
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
30
Registration Number
NCT03918252
Locations
🇺🇸

Johns Hopkins University, Baltimore, Maryland, United States

🇺🇸

University of Texas M.D. Anderson Cancer Center, Houston, Texas, United States

🇺🇸

Greenebaum Comprehensive Cancer Center University of Maryland School of Medicine, Baltimore, Maryland, United States

BGB-290 and Temozolomide in Treating Patients With Recurrent Gliomas With IDH1/2 Mutations

Phase 1
Completed
Conditions
Recurrent Glioblastoma
IDH2 Mutation
Recurrent WHO Grade III Glioma
IDH1 Mutation
Recurrent WHO Grade II Glioma
Interventions
Drug: PARP Inhibitor BGB-290
Procedure: Therapeutic Conventional Surgery
First Posted Date
2019-04-16
Last Posted Date
2025-01-14
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
67
Registration Number
NCT03914742
Locations
🇺🇸

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States

🇺🇸

University of Virginia, Charlottesville, Virginia, United States

🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

and more 9 locations

A Study of Pemigatinib in Non-muscle Invasive Bladder Cancer Patients With Recurrent Low- or Intermediate-Risk Tumors

Phase 2
Recruiting
Conditions
Bladder Cancer
NMIBC
Non-Muscle Invasive Bladder Cancer
Urothelial Carcinoma Recurrent
Interventions
First Posted Date
2019-04-16
Last Posted Date
2025-05-21
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
43
Registration Number
NCT03914794
Locations
🇺🇸

Associated Medical Professionals Urology, Syracuse, New York, United States

🇺🇸

Midlantic Urology, Bala-Cynwyd, Pennsylvania, United States

🇺🇸

Sibley Memorial Hospital, Washington, District of Columbia, United States

and more 3 locations

Non-Invasive Neurosensory Testing For Chemotherapy-Induced Peripheral Neuropathy

Completed
Conditions
Malignancy
Neuropathy
Chemotherapy-induced Peripheral Neuropathy
Neuropathies Sensory
Cancer
Malignant Neoplasm
Interventions
Device: Neurosensory testing with Pressure-Specified Sensory Device
First Posted Date
2019-04-10
Last Posted Date
2019-11-27
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
26
Registration Number
NCT03909464
Locations
🇺🇸

Johns Hopkins University School of Medicine, Baltimore, Maryland, United States

Neoadjuvant Dupilumab in Men With Localized High-Risk Prostate Cancer

Phase 2
Terminated
Conditions
Prostate Cancer
Interventions
First Posted Date
2019-03-22
Last Posted Date
2021-10-15
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
7
Registration Number
NCT03886493
Locations
🇺🇸

Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, United States

Preoperative Immune Checkpoint Inhibitor for Patients With Primary Untreated or Recurrent/Metastatic SCCHN

Phase 2
Completed
Conditions
Head and Neck Cancer Metastatic
Head and Neck Squamous Cell Carcinoma
Head and Neck Cancer
Interventions
First Posted Date
2019-03-18
Last Posted Date
2024-11-21
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
26
Registration Number
NCT03878979
Locations
🇺🇸

Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, United States

Dose-Escalation Study of E7727, an Oral Cytidine Deaminase Inhibitor With Oral Decitabine in Subjects With Solid Tumors

Phase 1
Recruiting
Conditions
Solid Tumor
Interventions
First Posted Date
2019-03-14
Last Posted Date
2025-03-04
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
35
Registration Number
NCT03875287
Locations
🇺🇸

USC Norris Comprehensive Cancer Center, Los Angeles, California, United States

🇺🇸

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States

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