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89bio

89bio logo
🇺🇸United States
Ownership
Public
Established
2018-01-01
Employees
70
Market Cap
$968M
Website
http://www.89bio.com

Clinical Trials

12

Active:5
Completed:4

Trial Phases

3 Phases

Phase 1:7
Phase 2:2
Phase 3:3

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (12 trials with phase data)• Click on a phase to view related trials

Phase 1
7 (58.3%)
Phase 3
3 (25.0%)
Phase 2
2 (16.7%)

Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH (ENLIGHTEN-Cirrhosis)

Phase 3
Recruiting
Conditions
Metabolic Dysfunction-Associated Steatohepatitis (MASH) with Compensated Cirrhosis
First Posted Date
2024-10-04
Last Posted Date
2025-05-28
Lead Sponsor
89bio Inc.
Target Recruit Count
155
Registration Number
2023-510395-31-00
Locations
🇵🇱

Santa Sp. z o.o., Lodz, Poland

🇵🇱

ID Clinic Arkadiusz Pisula, Myslowice, Poland

🇵🇱

Uniwersyteckie Centrum Kliniczne Im. Prof. K. Gibinskiego Slaskiego Uniwersytetu Medycznego W Katowicach, Katowice, Poland

and more 61 locations

A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

Phase 3
Recruiting
Conditions
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis
Interventions
First Posted Date
2024-03-19
Last Posted Date
2025-07-08
Lead Sponsor
89bio, Inc.
Target Recruit Count
1050
Registration Number
NCT06318169
Locations
🇬🇧

89bio Clinical Study Site, York, United Kingdom

To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia

Phase 3
Active, not recruiting
Conditions
Severe Hypertriglyceridemia
Interventions
Drug: Placebo
First Posted Date
2023-05-10
Last Posted Date
2025-02-28
Lead Sponsor
89bio, Inc.
Target Recruit Count
360
Registration Number
NCT05852431
Locations
🇬🇧

89bio Clinical Study Site, Cardiff, United Kingdom

🇵🇷

89Bio Clinical Study Site, San Juan, Puerto Rico

🇱🇻

89bio Clinical Trial Site, Riga, Latvia

and more 4 locations

PK Study of Liquid Formulation of BIO89-100 in Subjects With NASH With Compensation Cirrhosis

Phase 1
Completed
Conditions
NASH - Nonalcoholic Steatohepatitis
Interventions
First Posted Date
2021-08-26
Last Posted Date
2022-03-02
Lead Sponsor
89bio, Inc.
Target Recruit Count
8
Registration Number
NCT05022693
Locations
🇺🇸

89bio Clinical Study Site, Chandler, Arizona, United States

Study Evaluating the Safety, Efficacy and Tolerability of BIO89-100 in Subjects With Biopsy-confirmed Nonalcoholic Steatohepatitis (NASH)

Phase 2
Completed
Conditions
NASH - Nonalcoholic Steatohepatitis
Interventions
Drug: Placebo
First Posted Date
2021-06-18
Last Posted Date
2025-02-07
Lead Sponsor
89bio, Inc.
Target Recruit Count
222
Registration Number
NCT04929483
Locations
🇵🇷

89bio Clinical Study Site, San Juan, Puerto Rico

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News

NASH Treatment Market to Reach Significant Growth by 2032, Driven by Emerging Therapies

• The non-alcoholic steatohepatitis (NASH) market is poised for substantial growth, projected to expand significantly by 2032 across the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom), and Japan. • This growth is fueled by the introduction of novel therapies targeting NASH, with several drugs in Phase II and Phase III clinical trials showing promise for improving treatment outcomes. • Key players such as Madrigal Pharmaceuticals, Intercept Pharmaceuticals, and Novo Nordisk are actively developing innovative treatments, contributing to a dynamic and competitive market landscape. • The increasing prevalence of NASH and the growing understanding of its pathophysiology are driving the demand for effective therapies, creating opportunities for pharmaceutical companies.

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