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Akari Therapeutics

Akari Therapeutics logo
🇬🇧United Kingdom
Ownership
Public
Established
2004-01-01
Employees
12
Market Cap
-
Website
http://www.akaritx.com

Nomacopan Therapy in Adult Patients With Bullous Pemphigoid Receiving Adjunct Oral Corticosteroid Therapy (ARREST-BP)

Phase 3
Withdrawn
Conditions
Bullous Pemphigoid
Interventions
First Posted Date
2021-09-30
Last Posted Date
2024-02-08
Lead Sponsor
AKARI Therapeutics
Registration Number
NCT05061771
Locations
🇺🇸

Tulane University Health Sciences Center, Los Angeles, California, United States

🇺🇸

North Shore University Health System, Skokie, Illinois, United States

🇺🇸

Dawes Fretzin Clinical Research Group LLC, Indianapolis, Indiana, United States

and more 9 locations

Nomacopan (rVA576) in Transplant Associated Thrombotic Microangiopathy

Phase 3
Terminated
Conditions
Thrombotic Microangiopathies
Interventions
First Posted Date
2021-03-05
Last Posted Date
2024-07-16
Lead Sponsor
AKARI Therapeutics
Target Recruit Count
10
Registration Number
NCT04784455
Locations
🇬🇧

St. Georges University Hospital, London, United Kingdom

🇺🇸

Children's Hospital Los Angeles, Los Angeles, California, United States

🇺🇸

Duke University Medical Center, Children's Health Center, Durham, North Carolina, United States

and more 6 locations

Topical rVA576 for Treatment of Atopic Keratoconjunctivitis

Phase 1
Terminated
Conditions
Atopic Keratoconjunctivitis (AKC)
Interventions
Drug: rVA576
Other: Placebo
First Posted Date
2019-07-30
Last Posted Date
2021-03-18
Lead Sponsor
AKARI Therapeutics
Target Recruit Count
12
Registration Number
NCT04037891
Locations
🇬🇧

Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom

rVA576 in Adult Mild to Moderate Bullous Pemphigoid Subjects

Phase 2
Completed
Conditions
Bullous Pemphigoid (BP)
Interventions
Drug: rVA576
First Posted Date
2019-07-29
Last Posted Date
2021-06-28
Lead Sponsor
AKARI Therapeutics
Target Recruit Count
9
Registration Number
NCT04035733
Locations
🇳🇱

UMCG Groningen, Groningen, Hanzeplein 1, Netherlands

🇩🇪

University of Lubeck, Lubeck, Germany

rVA576 (Coversin) Long Term Safety and Efficacy Surveillance Study

Phase 3
Terminated
Conditions
Paroxysmal Nocturnal Hemoglobinuria
Interventions
Drug: rVA576 (Coversin)
First Posted Date
2019-02-04
Last Posted Date
2021-06-28
Lead Sponsor
AKARI Therapeutics
Target Recruit Count
15
Registration Number
NCT03829449
Locations
🇵🇱

Instytut Hematologii i Transfuzjologii, Warsaw, Poland

Treating Paroxysmal Nocturnal Haemoglobinuria Patients With rVA576

Phase 3
Completed
Conditions
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions
Drug: rVA576
Other: Standard of care (SOC)
First Posted Date
2018-07-17
Last Posted Date
2020-11-04
Lead Sponsor
AKARI Therapeutics
Target Recruit Count
9
Registration Number
NCT03588026
Locations
🇱🇰

University of Kelaniya, Faculty of Medicine, Thalagolla Road, Colombo, Sri Lanka

🇰🇿

Almaty City Hospital No.7, Almaty, Microdistrict Kalkaman, Kazakhstan

🇱🇹

Vilnius University Hospital Santaros Klinikos , Santariškių St. 2, LT-08661,, Vilnius, Lithuania

Coversin in PNH in Patients With Resistance to Eculizumab Due to Complement C5 Polymorphisms

Phase 2
Completed
Conditions
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions
First Posted Date
2018-02-09
Last Posted Date
2024-12-20
Lead Sponsor
AKARI Therapeutics
Target Recruit Count
1
Registration Number
NCT03427060
Locations
🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

Coversin in Paroxysmal Nocturnal Haemoglobinuria (PNH)

Phase 2
Completed
Conditions
Paroxysmal Nocturnal Haemoglobinuria (PNH)
Interventions
First Posted Date
2015-10-30
Last Posted Date
2023-07-12
Lead Sponsor
AKARI Therapeutics
Target Recruit Count
1
Registration Number
NCT02591862
Locations
🇳🇱

Dr Saskia Langemeijer, Nijmegen, Netherlands

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