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TC BioPharm

🇬🇧United Kingdom
Ownership
-
Employees
41
Market Cap
-
Website
Introduction

TC Biopharm (Holdings) Plc is a clinical-stage biopharmaceutical company, which engages in the development of novel immunotherapy products based on its proprietary allogeneic gamma delta T cell platform. The company was founded by Michael Leek and Angela Scott in 2013 and is headquartered in Motherwell, the United Kingdom.

Clinical Trials

6

Active:0
Completed:2

Trial Phases

2 Phases

Phase 1:2
Phase 2:3

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (5 trials with phase data)• Click on a phase to view related trials

Phase 2
3 (60.0%)
Phase 1
2 (40.0%)

ACHIEVE2 - Safety and Preliminary Efficacy of Intravenous TCB008 in Patients With Relapse or Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)/AML

Phase 1
Not yet recruiting
Conditions
Acute Myeloid Leukemia
Myelodysplastic Syndromes
Interventions
First Posted Date
2024-06-17
Last Posted Date
2024-06-17
Lead Sponsor
TC Biopharm
Target Recruit Count
69
Registration Number
NCT06463327

ACHIEVE - Efficacy and Effectiveness of Adoptive Cellular tHerapy wIth Ex-Vivo Expanded Allogeneic γδ T-lymphocytes (TCB008) for Patients With Refractory or Relapsed Acute Myeloid Leukaemia (AML)

Phase 2
Recruiting
Conditions
Acute Myeloid Leukemia
Myelodysplastic Syndromes
Interventions
First Posted Date
2022-05-03
Last Posted Date
2024-06-21
Lead Sponsor
TC Biopharm
Target Recruit Count
53
Registration Number
NCT05358808
Locations
🇬🇧

Bristol and Weston NHS foundation trust, Bristol, United Kingdom

🇬🇧

Cardiff and Vale University LHB, Cardiff, United Kingdom

🇬🇧

Queen Elizabeth University Hospital, Glasgow, United Kingdom

and more 3 locations

A Phase II Safety and Tolerability Study of TCB008 in Patients With COVID-19

Phase 2
Withdrawn
Conditions
COVID - 19
Interventions
First Posted Date
2021-04-06
Last Posted Date
2023-04-21
Lead Sponsor
TC Biopharm
Registration Number
NCT04834128
Locations
🇬🇧

Royal Victoria Infirmary, Newcastle, United Kingdom

Ex-vivo Expanded γδ T-lymphocytes (OmnImmune®) in Patients With Acute Myeloid Leukaemia (AML)

Phase 1
Completed
Conditions
Acute Myeloid Leukemia
First Posted Date
2018-12-31
Last Posted Date
2021-03-30
Lead Sponsor
TC Biopharm
Target Recruit Count
10
Registration Number
NCT03790072
Locations
🇨🇿

UHKT (Ustav hematologie a krevni transfuze), Praha, Czechia

ImmuniCell® in Patients With Advanced Cancers

Phase 2
Terminated
Conditions
Malignant Melanoma
Non-small Cell Lung Cancer
Renal Cell Cancer
First Posted Date
2015-06-01
Last Posted Date
2022-03-10
Lead Sponsor
TC Biopharm
Target Recruit Count
8
Registration Number
NCT02459067
Locations
🇬🇧

Velindre Cancer Centre and University Hospital of Wales, Cardiff, United Kingdom

🇬🇧

Western General Hospital, Edinburgh, United Kingdom

🇬🇧

Beatson West of Scotland Cancer Centre, Glasgow, United Kingdom

and more 4 locations

News

TC Biopharm Leads Gamma Delta T Cell Therapy Development with Over 25 Clinical Programs Worldwide

TC Biopharm's OmnImmune is advancing through a pivotal Phase 2/3 trial for acute myeloid leukemia, representing one of the most advanced gamma delta T cell therapies globally.

Allogeneic Cell Therapies Emerge as Next-Generation Cancer Treatment to Address Manufacturing and Cost Challenges

Allogeneic "off-the-shelf" cell therapies are being developed to overcome the complex manufacturing and supply chain limitations of current autologous CAR-T treatments, which require 9-14 days to produce individualized therapies.

TC BioPharm to Acquire Ophthalmic Pharmaceutical Company with FDA-Approved Glaucoma Treatment

TC BioPharm has signed a non-binding letter of intent to acquire a commercial-stage ophthalmic pharmaceutical company with an FDA-approved once-daily eye drop for glaucoma and ocular hypertension.

CareDx and TC BioPharm Partner to Enhance AlloCell Monitoring in AML Trial

CareDx partners with TC BioPharm to perform pharmacokinetic analysis in the ACHIEVE clinical trial using its AlloCell solution.

TC BioPharm's TCB008 Shows Promise in Phase 2b ACHIEVE Trial for Acute Myeloid Leukemia

TC BioPharm's ACHIEVE Phase 2b trial evaluates TCB008 for acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS/AML).

TC BioPharm Expands ACHIEVE AML Trial with New Site at Guys and St. Thomas Hospital

TC BioPharm has opened a new clinical trial site at Guys and St. Thomas Hospital in London to accelerate enrollment in the ACHIEVE study.

TC BioPharm's TCB008 Shows Promising Safety Profile in ACHIEVE Trial for AML/MDS

TC BioPharm announced the first patient completed the full dosing regimen of TCB008 in the ACHIEVE Phase 2b trial without drug-related adverse events.

TC BioPharm to Explore Gamma Delta T-Cell Therapy TCB008 for Mpox Treatment

TC BioPharm is initiating preclinical studies for TCB008, an unmodified cell therapy, to treat Mpox, leveraging the role of gamma delta T-cells in viral infections.

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