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Regeneron Pharmaceuticals

Regeneron Pharmaceuticals logo
πŸ‡ΊπŸ‡ΈUnited States
Ownership
Public
Established
1988-01-01
Employees
13.4K
Market Cap
$132.4B
Website
http://www.regeneron.com
Introduction

Regeneron Pharmaceuticals, Inc. is a biotechnology company, which engages in the discovery, invention, development, manufacture, and commercialization of medicines. Its product portfolio includes the following brands: Dupixent, Evkeeza, Eylea, Inmazeb, and Kevzara. The firm accelerates the traditional drug development process through its proprietary VelociSuite technologies such as VelocImmune, which uses unique genetically humanized mice to produce optimized fully human antibodies and bispecific antibodies. The company was founded by Alferd G. Gilman, Leonard S. Schleifer, George Damis Yancopoulos, and Eric M. Shooter on January 8, 1988, and is headquartered in Tarrytown, NY.

Cemiplimab and ISA101b Vaccine in Adult Participants With Recurrent/Metastatic Human Papillomavirus (HPV)16 Cervical Cancer Who Have Experienced Disease Progression After First Line Chemotherapy

Phase 2
Active, not recruiting
Conditions
Cervical Cancer
Interventions
First Posted Date
2020-11-27
Last Posted Date
2023-10-03
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
113
Registration Number
NCT04646005
Locations
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Arizona Oncology Associates, Tucson, Arizona, United States

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Universitair Ziekenhuis Gent, Gent, East Flanders, Belgium

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CHIREC Delta Hospital / Chirec Cancer Institute, Brussels, Belgium

and more 22 locations

CMP-001 in Combination With Pembrolizumab in Subjects With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Phase 2
Terminated
Conditions
Squamous Cell Carcinoma of Head and Neck
Interventions
First Posted Date
2020-11-18
Last Posted Date
2025-05-11
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT04633278
Locations
πŸ‡ΊπŸ‡Έ

University of Chicago Medical Center, Chicago, Illinois, United States

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University of Southern California: Norris Oncology/Hematology - Newport Beach, Newport Beach, California, United States

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University of California - San Diego, La Jolla, California, United States

and more 16 locations

A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancers

Phase 1
Recruiting
Conditions
Advanced Solid Tumors
Interventions
Drug: Platinum-based doublet chemotherapy
Drug: Trifluridine-tipiracil
First Posted Date
2020-11-12
Last Posted Date
2025-05-11
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
933
Registration Number
NCT04626635
Locations
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Hospital 12 de Octubre, Madrid, Spain

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Netherlands Cancer Institute, Amsterdam, Netherlands

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Valkyrie Clinical Trials, Los Angeles, California, United States

and more 45 locations

Compassionate Use of REGN-COV2 for the Treatment of COVID-19

Conditions
COVID-19
First Posted Date
2020-11-05
Last Posted Date
2023-10-03
Lead Sponsor
Regeneron Pharmaceuticals
Registration Number
NCT04617535

Study of the Safety, Tolerability, and Pharmacokinetics of REGN6490 in Healthy Japanese Adult Volunteers

Phase 1
Terminated
Conditions
Healthy Volunteer
Interventions
Drug: Placebo
First Posted Date
2020-11-04
Last Posted Date
2021-11-11
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
19
Registration Number
NCT04616105
Locations
πŸ‡ΊπŸ‡Έ

Regeneron Study Site, Glendale, California, United States

Ascending Dose Study of the Safety and Tolerability of REGN6490 in Healthy Volunteers

Phase 1
Terminated
Conditions
Healthy Volunteer
Interventions
Drug: Placebo
First Posted Date
2020-11-04
Last Posted Date
2021-11-11
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
57
Registration Number
NCT04616079
Locations
πŸ‡§πŸ‡ͺ

Regeneron Study Site, Ghent, Belgium

T Cell Receptor (TCR) Sequencing and Transcriptional Profiling in Adult Celiac Disease Patients Undergoing Gluten Challenge

Not Applicable
Completed
Conditions
Celiac Disease
Interventions
Dietary Supplement: Gluten Powder
First Posted Date
2020-11-04
Last Posted Date
2024-06-27
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT04614571
Locations
πŸ‡ΊπŸ‡Έ

Celiac Research Centre Mass General Hospital, Boston, Massachusetts, United States

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Pozelimab in Combination With Cemdisiran in Healthy Adult Volunteers

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2020-10-26
Last Posted Date
2021-11-12
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
19
Registration Number
NCT04601844
Locations
πŸ‡§πŸ‡ͺ

Regeneron Research Site, Antwerp, Belgium

A Trial to Find Out How Safe REGN5668 is and How Well it Works When Given With Either Cemiplimab or REGN4018

Phase 1
Recruiting
Conditions
Ovarian Cancer
Fallopian Tube Cancer
Primary Peritoneal Cancer
Endometrial Cancer
Interventions
First Posted Date
2020-10-19
Last Posted Date
2025-04-10
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
612
Registration Number
NCT04590326
Locations
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Hopital Lyon Sud, Pierre-Benite, Lyon, France

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Institut Gustave Roussy, Villejuif, France

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The City of Hope Orange County Lennar Foundation Cancer Center, Irvine, California, United States

and more 20 locations

Study to Assess the Efficacy and Safety of Garetosmab in Japanese Adult Patients With Fibrodysplasia Ossificans Progressiva (FOP)

Phase 3
Withdrawn
Conditions
Fibrodyplasia Ossificans Progressiva (FOP)
Heterotopic Ossification (HO)
Interventions
First Posted Date
2020-10-08
Last Posted Date
2021-11-01
Lead Sponsor
Regeneron Pharmaceuticals
Registration Number
NCT04577820
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