MedPath

Regeneron Pharmaceuticals

Regeneron Pharmaceuticals logo
🇺🇸United States
Ownership
Public
Established
1988-01-01
Employees
13.4K
Market Cap
$132.4B
Website
http://www.regeneron.com
Introduction

Regeneron Pharmaceuticals, Inc. is a biotechnology company, which engages in the discovery, invention, development, manufacture, and commercialization of medicines. Its product portfolio includes the following brands: Dupixent, Evkeeza, Eylea, Inmazeb, and Kevzara. The firm accelerates the traditional drug development process through its proprietary VelociSuite technologies such as VelocImmune, which uses unique genetically humanized mice to produce optimized fully human antibodies and bispecific antibodies. The company was founded by Alferd G. Gilman, Leonard S. Schleifer, George Damis Yancopoulos, and Eric M. Shooter on January 8, 1988, and is headquartered in Tarrytown, NY.

Single-dose Study to Describe the Pharmacodynamics (PD) and Safety of Sarilumab (REGN88/SAR153191) and Tocilizumab in Adults With Rheumatoid Arthritis (RA)

Phase 1
Completed
Conditions
Rheumatoid Arthritis
Interventions
First Posted Date
2014-03-27
Last Posted Date
2015-05-05
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
105
Registration Number
NCT02097524

Phase 1 Safety Study With Intravitreal (IVT) REGN2176-3 in Patients Aged 50 Years and Older With Wet AMD

Phase 1
Completed
Conditions
Neovascular Wet Age-related Macular Degeneration (AMD)
Interventions
First Posted Date
2014-02-13
Last Posted Date
2015-02-11
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
12
Registration Number
NCT02061865

Study of Intravitreal (IVT) REGN910-3 and IVT REGN910 in Patients With Either Neovascular ("Wet") Age Related Macular Degeneration (AMD) or Diabetic Macular Edema (DME)

Phase 1
Completed
Conditions
Diabetic Macular Edema
Neovascular Age-Related Macular Degeneration
Interventions
Drug: Intravitreal Aflibercept Injection (IAI)
First Posted Date
2013-11-27
Last Posted Date
2016-01-12
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
20
Registration Number
NCT01997164

Study to Determine the Safety and Effectiveness of Dupilumab for Treatment of Atopic Dermatitis (AD)

Phase 2
Completed
Conditions
Atopic Dermatitis (AD)
Interventions
Drug: Placebo
Other: Background treatment
First Posted Date
2013-11-08
Last Posted Date
2020-03-18
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
54
Registration Number
NCT01979016

Study of the Safety and Efficacy of REGN1033 (SAR391786) in Patients With Sarcopenia

Phase 2
Completed
Conditions
Sarcopenia
Interventions
Drug: REGN1033 (SAR391786)
Drug: placebo
First Posted Date
2013-10-16
Last Posted Date
2016-03-28
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
253
Registration Number
NCT01963598

Open-label Study of Dupilumab in Patients With Atopic Dermatitis

Phase 3
Completed
Conditions
Atopic Dermatitis
Interventions
First Posted Date
2013-09-24
Last Posted Date
2023-10-17
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
2733
Registration Number
NCT01949311
Locations
🇵🇱

Regeneron Study Site 5, Warszawa, Mazowieckie, Poland

🇪🇸

Regeneron Study Site 4, Barcelona, Spain

🇬🇧

Regeneron Study Site 1, London, United Kingdom

and more 6 locations

An Ascending Single-Dose Study of the Safety, Tolerability and Bioeffect of REGN1193

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Other: Placebo
First Posted Date
2013-09-02
Last Posted Date
2015-03-13
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
56
Registration Number
NCT01933763

Study to Evaluate the Efficacy and Safety of an Every Four Weeks Treatment Regimen of Alirocumab (REGN727/ SAR236553) in Patients With Primary Hypercholesterolemia (ODYSSEY CHOICE 1)

Phase 3
Completed
Conditions
Hypercholesterolemia
Interventions
Drug: Placebo (for alirocumab)
First Posted Date
2013-08-21
Last Posted Date
2017-03-21
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
803
Registration Number
NCT01926782

Single Ascending-dose Study of the Safety, Tolerability, and Pharmacokinetics of REGN1908-1909 in Allergic, Adult Subjects

Phase 1
Completed
Conditions
Allergy
Interventions
Other: placebo
First Posted Date
2013-08-14
Last Posted Date
2014-06-10
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT01922661

Study to Assess the Safety and Bioeffect of REGN1033 (SAR391786)

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Other: placebo
Drug: REGN1033 (SAR391786)
First Posted Date
2013-07-29
Last Posted Date
2014-11-10
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
125
Registration Number
NCT01910220
© Copyright 2025. All Rights Reserved by MedPath