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Regeneron Pharmaceuticals

Regeneron Pharmaceuticals logo
🇺🇸United States
Ownership
Public
Established
1988-01-01
Employees
13.4K
Market Cap
$132.4B
Website
http://www.regeneron.com
Introduction

Regeneron Pharmaceuticals, Inc. is a biotechnology company, which engages in the discovery, invention, development, manufacture, and commercialization of medicines. Its product portfolio includes the following brands: Dupixent, Evkeeza, Eylea, Inmazeb, and Kevzara. The firm accelerates the traditional drug development process through its proprietary VelociSuite technologies such as VelocImmune, which uses unique genetically humanized mice to produce optimized fully human antibodies and bispecific antibodies. The company was founded by Alferd G. Gilman, Leonard S. Schleifer, George Damis Yancopoulos, and Eric M. Shooter on January 8, 1988, and is headquartered in Tarrytown, NY.

Clinical Trials

750

Active:368
Completed:221

Trial Phases

5 Phases

Phase 1:436
Phase 2:104
Phase 3:99
+2 more phases

Drug Approvals

5

FDA:5

Drug Approvals

Praluent

Approval Date
Mar 8, 2024
FDA

LIBTAYO

Approval Date
Mar 4, 2024
FDA

EYLEA

Approval Date
Dec 14, 2023
FDA

Evkeeza

Approval Date
Mar 30, 2023
FDA

Inmazeb

Approval Date
Dec 20, 2022
FDA

Clinical Trials

Distribution across different clinical trial phases (667 trials with phase data)• Click on a phase to view related trials

Phase 1
436 (65.4%)
Phase 2
104 (15.6%)
Phase 3
99 (14.8%)
Not Applicable
12 (1.8%)
Phase 4
10 (1.5%)
phase_1_2
4 (0.6%)
phase_2_3
2 (0.3%)

First-in-Human Study of ALN-SNCA in Adult Participants With Early Parkinson's Disease (PD)

Not Applicable
Not yet recruiting
Conditions
Parkinsons Disease
Interventions
Drug: ALN-SNCA
Drug: Placebo
First Posted Date
2025-10-14
Last Posted Date
2025-10-14
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
46
Registration Number
NCT07216066

REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants

Not Applicable
Not yet recruiting
Conditions
Symptomatic Venous Thromboembolism (VTE)
Interventions
Drug: Acetylsalicylic Acid (ASA)
Drug: Placebo
First Posted Date
2025-10-09
Last Posted Date
2025-10-09
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
2000
Registration Number
NCT07213778

A First-in-Human Safety and Efficacy Study of ALN-CFB, a Small Interfering RNA (siRNA) Targeting Complement Factor B, in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria With Persistent Anemia on a C5 Inhibitor

Not Applicable
Not yet recruiting
Conditions
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Persistent Anemia
Interventions
Drug: ALN-CFB
Drug: Placebo
First Posted Date
2025-09-23
Last Posted Date
2025-09-23
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT07187401

Study of Growth and Bone Mineral Density in Children With Atopic Dermatitis (AD) Treated With Dupilumab

Not Applicable
Not yet recruiting
Conditions
Severe Atopic Dermatitis (AD)
Interventions
First Posted Date
2025-09-22
Last Posted Date
2025-09-22
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
85
Registration Number
NCT07187089

Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation

Not Applicable
Not yet recruiting
Conditions
Atrial Fibrillation (AF)
Interventions
First Posted Date
2025-09-16
Last Posted Date
2025-09-16
Lead Sponsor
Regeneron Pharmaceuticals
Target Recruit Count
1200
Registration Number
NCT07175428
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News

Excellergy Raises $70M Series A to Advance Novel Trifunctional Allergy Treatment Platform

Excellergy secured $70 million in Series A funding to develop first-in-class trifunctional Effector Cell Response Inhibitors (ECRIs) for allergic conditions.

Regeneron's DB-OTO Gene Therapy Restores Hearing in 11 of 12 Children with Genetic Hearing Loss

Regeneron's investigational gene therapy DB-OTO demonstrated clinically meaningful hearing improvements in 11 of 12 children with profound genetic hearing loss due to OTOF gene variants in the pivotal CHORD trial.

Eli Lilly and AstraZeneca Emerge as Leading Candidates for Next Trump Administration Drug Pricing Deal

Wall Street analysts predict Eli Lilly and AstraZeneca are the most likely pharmaceutical companies to strike the next drug pricing deal with the Trump administration following Pfizer's September 29 agreement.

Amgen's Repatha Demonstrates Long-Term Cardiovascular Benefits in Phase III VESALIUS-CV Trial

Amgen's Phase III VESALIUS-CV trial met both primary endpoints, demonstrating that Repatha significantly reduces major adverse cardiovascular events in high-risk patients without prior heart attack or stroke.

MiNK Therapeutics Appoints Dr. Terese Hammond to Lead iNKT Cell Therapy Pipeline Toward Pivotal Trials

MiNK Therapeutics has appointed Dr. Terese C. Hammond as Head of Inflammatory and Pulmonary Diseases to accelerate their invariant natural killer T (iNKT) cell therapy pipeline toward pivotal development.

Regeneron's Garetosmab Achieves 90% Reduction in Bone Formation in Rare Disease Trial

Regeneron's Phase 3 OPTIMA trial of garetosmab met its primary endpoint, demonstrating a 90% or greater reduction in new heterotopic ossification lesions in adults with fibrodysplasia ossificans progressiva at 56 weeks.

Ollin Biosciences Emerges with $100M to Challenge Leading Eye Disease Treatments

Ollin Biosciences launched with $100 million in Series A funding led by ARCH Venture Partners, Mubadala Capital, and Monograph Capital to develop next-generation ophthalmology treatments.

Dualitas Therapeutics Emerges from Stealth with $65M Series A to Advance Bispecific Antibody Pipeline

Dualitas Therapeutics launched from stealth with $65 million Series A funding co-led by Versant Ventures and Qiming Venture Partners USA, with participation from Eli Lilly and Company and other strategic investors.

Australian Court Denies Preliminary Injunction Against Sandoz Aflibercept Biosimilar Launch

The Federal Court of Australia denied Regeneron and Bayer's preliminary injunction application against Sandoz's aflibercept biosimilars, allowing the launch of Afqlir and Enzeevu to proceed as planned.

Regeneron's Libtayo Combination Therapy Demonstrates 19.4% Five-Year Survival Rate in Advanced Lung Cancer

Regeneron's Phase 3 EMPOWER-Lung 3 trial shows Libtayo plus chemotherapy achieved a 19.4% five-year survival rate compared to 8.8% with chemotherapy alone in advanced non-small cell lung cancer patients.

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