To Assess the Effect of the Special Condition on the Pharmacokinetics and Tolerability of the Esflurbiprofen Topical System (EFTS) in Healthy Volunteers.
- Conditions
- Healthy
- Interventions
- Drug: Esflurbiprofen Topical System
- First Posted Date
- 2025-03-11
- Last Posted Date
- 2025-04-22
- Lead Sponsor
- Teikoku Seiyaku Co., Ltd.
- Target Recruit Count
- 28
- Registration Number
- NCT06870422
- Locations
- 🇩🇪
SocraTec R&D GmbH Clinical Pharmacology Unit, Mainzerhofplatz, Erfurt, Germany
Phase III Trial to Assess the Safety and Efficacy of TK-254RX in Patients With Contusions
- Conditions
- Contusions
- Interventions
- Drug: Esflurbiprofen Topical System (EFTS)
- First Posted Date
- 2025-03-11
- Last Posted Date
- 2025-04-18
- Lead Sponsor
- Teikoku Seiyaku Co., Ltd.
- Target Recruit Count
- 219
- Registration Number
- NCT06871046
- Locations
- 🇩🇪
Medical Practice Ebert, Siemensstr, Bonn, Germany
🇩🇪Medical Practice Prof. Predel, Siemensstr, Bonn, Germany
🇩🇪Medical Practice Schaale-Maas, Siemensstr, Bonn, Germany
Phase III Trial to Evaluate the Efficacy and Safety in Patients With Ankle Sprains.
- Conditions
- Ankle Sprains
- Interventions
- Drug: Esflurbiprofen Topical System (EFTS)Drug: Placebo Patch
- First Posted Date
- 2025-03-10
- Last Posted Date
- 2025-04-18
- Lead Sponsor
- Teikoku Seiyaku Co., Ltd.
- Target Recruit Count
- 69
- Registration Number
- NCT06866613
- Locations
- 🇩🇪
Medical Practice Ebert, Siemensstr, Bonn, Germany
🇩🇪Medical Practice Prof. Predel, Siemensstr, Bonn, Germany
🇩🇪Medical Practice Schaale-Maas, Siemensstr, Bonn, Germany
To Assess the Bioavailability of TK-254RX in Comparison with Oral Flurbiprofen Tablets and the Adhesion of TK-254RX in Healthy Subjects
- Conditions
- Healthy
- Interventions
- Drug: Esflurbiprofen Topical SystemDrug: Flurbiprofen tablet
- First Posted Date
- 2025-02-12
- Last Posted Date
- 2025-03-11
- Lead Sponsor
- Teikoku Seiyaku Co., Ltd.
- Target Recruit Count
- 26
- Registration Number
- NCT06823284
- Locations
- 🇩🇪
SocraTec R&D GmbH Clinical Pharmacology Unit, Mainzerhofplatz 14, Erfurt, Germany
Open Label Trial to Evaluate the Adhesion of TK-254RX in Healthy Volunteers.
- First Posted Date
- 2023-09-18
- Last Posted Date
- 2024-04-12
- Lead Sponsor
- Teikoku Seiyaku Co., Ltd.
- Target Recruit Count
- 80
- Registration Number
- NCT06042192
- Locations
- 🇩🇪
Medical Practice Ebert, Brühl, Germany
🇩🇪Medical practice Pabst, Fürstenfeldbruck, Germany
🇩🇪Medical practice Gastl, Gilching, Germany
Efficacy and Safety of Esflurbiprofen Hydrogel Patch in the Treatment of Local Acute Pain
- Conditions
- Soft Tissue InjuriesContusionsStrainsSprainsBruises
- Interventions
- First Posted Date
- 2021-06-01
- Last Posted Date
- 2023-09-28
- Lead Sponsor
- Teikoku Seiyaku Co., Ltd.
- Target Recruit Count
- 200
- Registration Number
- NCT04908748
- Locations
- 🇩🇪
Deutsche Sporthochschule Köln Institut für Kreislaufforschung und Sportmedizin, Cologne, NRW, Germany
Proof-of-concept Study of NSAID Hydrogel Patch in Treatment of Acute Pain
- First Posted Date
- 2016-04-06
- Last Posted Date
- 2021-10-19
- Lead Sponsor
- Teikoku Seiyaku Co., Ltd.
- Target Recruit Count
- 6
- Registration Number
- NCT02729207
- Locations
- 🇺🇸
SNBL Clinical Pharmacology Center, Baltimore, Maryland, United States