CHILDREN'S HOSPITAL OF ORANGE COUNTY

🇺🇸United States

Country: 🇺🇸United States

Ownership: Private

Established: 1964-01-01

Employees: -

Market Cap: -

Website: http://www.choc.org

Clinical Trials

Exparel vs. ACB With Bupivacaine for ACL Reconstruction

Phase 1

Recruiting

Conditions: ACL Tear
Opioid Misuse
Pain
Anxiety

Interventions: Drug: Exparel

First Posted Date: 2024-02-23

Last Posted Date: 2024-02-23

Lead Sponsor: Children's Hospital of Orange County

Target Recruit Count: 96

Registration Number: NCT06274008

Locations: 🇺🇸
CHOC Children's Hospital, Orange, California, United States

Peppermint Oil as a Treatment for Children With Bladder and Bowel Dysfunction

Not Applicable

Conditions: Bladder and Bowel Dysfunction

Interventions: Dietary Supplement: Peppermint Oil

First Posted Date: 2022-11-14

Last Posted Date: 2024-02-07

Lead Sponsor: Children's Hospital of Orange County

Target Recruit Count: 30

Registration Number: NCT05613153

Locations: 🇺🇸
Children's Hospital, Orange County, Orange, California, United States

Use of Levocarnitine to Reduce Asparaginase Hepatotoxicity in Patients With Acute Lymphoblastic Leukemia

Early Phase 1

Recruiting

Conditions: Acute Lymphoblastic Leukemia
Hepatotoxicity

Interventions: Drug: Levocarnitine

First Posted Date: 2022-08-16

Last Posted Date: 2024-08-21

Lead Sponsor: Children's Hospital of Orange County

Target Recruit Count: 20

Registration Number: NCT05501899

Locations: 🇺🇸
Children's Hospital of Orange County, Orange, California, United States
🇺🇸
Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange, California, United States

Cardiovascular Structure and Function in the Mucopolysaccharidoses

Recruiting

Conditions: Carotid Disease
Inflammation
Mucopolysaccharidoses
Cardiac Disease

First Posted Date: 2021-10-01

Last Posted Date: 2023-08-30

Lead Sponsor: Children's Hospital of Orange County

Target Recruit Count: 30

Registration Number: NCT05063435

Locations: 🇺🇸
Children's Hospital of Orange County, Orange, California, United States

Percutaneous Electrical Nerve Field Stimulation (PENFS) in Patients With Post Concussion Syndrome (PCS)

Not Applicable

Recruiting

Conditions: COVID Long-Haul
COVID-19
Post-Concussion Syndrome

Interventions: Device: percutaneous electrical nerve-field stimulation, PENFS (sham device)
Device: percutaneous electrical nerve-field stimulation, PENFS
Device: percutaneous electrical nerve-field stimulation, PENFS (COVID active device)

First Posted Date: 2021-07-27

Last Posted Date: 2023-09-26

Lead Sponsor: Children's Hospital of Orange County

Target Recruit Count: 125

Registration Number: NCT04978571

Locations: 🇺🇸
CHOC Children's, Orange, California, United States

Ganglioside and IBD

Not Applicable

Conditions: Inflammatory Bowel Diseases

Interventions: Other: Anhydrous Milk Fat
Other: Buttermilk Powder

First Posted Date: 2021-03-04

Last Posted Date: 2022-07-27

Lead Sponsor: Children's Hospital of Orange County

Target Recruit Count: 48

Registration Number: NCT04782544

Locations: 🇺🇸
Children's Hospital of Orange County, Orange, California, United States

Comparison of microMend® Devices to Sutures in Closing Lacerations in Children

Not Applicable

Conditions: Laceration
Skin Wound
Wound Heal

Interventions: Device: Closure with Sutures
Device: microMend®

First Posted Date: 2020-09-22

Last Posted Date: 2022-03-28

Lead Sponsor: Children's Hospital of Orange County

Target Recruit Count: 30

Registration Number: NCT04557761

Locations: 🇺🇸
CHOC Children's, Orange, California, United States

Utility of Pupillary Metrics in Diagnosis and Management of Concussion in Children

Conditions: Brain Concussion
Post-Concussion Syndrome
Reflex, Pupillary
Brain Injuries, Traumatic

Interventions: Other: Pupillary Assessment

First Posted Date: 2020-09-07

Last Posted Date: 2022-03-11

Lead Sponsor: Children's Hospital of Orange County

Target Recruit Count: 130

Registration Number: NCT04540445

Locations: 🇺🇸
CHOC Children's, Orange, California, United States

Comparison of 2 Application Techniques for LET Gel Used Prior to Simple Laceration Repair

Phase 4

Completed

Conditions: LET
Laceration of Skin

Interventions: Drug: LET (lidocaine 4%; epinephrine 0.1%; tetracaine 0.5%) gel (1 application)
Drug: LET (lidocaine 4%; epinephrine 0.1%; tetracaine 0.5%) gel (3 applications)

First Posted Date: 2020-09-02

Last Posted Date: 2020-09-02

Lead Sponsor: Children's Hospital of Orange County

Target Recruit Count: 48

Registration Number: NCT04536493

Locations: 🇺🇸
CHOC Children's, Orange, California, United States

Treatment of Refractory Infantile Spasms With Fenfluramine

Phase 2

Recruiting

Conditions: Infantile Spasm

Interventions: Drug: Fenfluramine

First Posted Date: 2020-02-28

Last Posted Date: 2024-02-07

Lead Sponsor: Children's Hospital of Orange County

Target Recruit Count: 10

Registration Number: NCT04289467

Locations: 🇺🇸
UCLA Health, Los Angeles, California, United States
🇺🇸
Children's Hospital of Orange County, Orange, California, United States

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