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Atossa Therapeutics

Atossa Therapeutics logo
🇺🇸United States
Ownership
Public
Established
2009-01-01
Employees
12
Market Cap
$169.7M
Website
http://www.atossatherapeutics.com
Introduction

Atossa Therapeutics, Inc. operates as a clinical-stage pharmaceutical company, which engages in the development of novel therapeutics and delivery methods for the treatment of breast cancer and other breast conditions. The company was founded by Steven C. Quay and Shu Chih Chen in December 2008 and is headquartered in Seattle, WA.

Clinical Trials

10

Active:2
Completed:5

Trial Phases

3 Phases

Phase 1:3
Phase 2:4
Phase 3:1

Drug Approvals

0

Drug Approvals

No drug approvals found

This company may not have drug approvals in our database

Clinical Trials

Distribution across different clinical trial phases (8 trials with phase data)• Click on a phase to view related trials

Phase 2
4 (50.0%)
Phase 1
3 (37.5%)
Phase 3
1 (12.5%)

(Z)-Endoxifen for the Treatment of Premenopausal Women With ER+/HER2- Breast Cancer

Phase 2
Recruiting
Conditions
Breast Neoplasms
Invasive Breast Cancer
Estrogen-receptor-positive Breast Cancer
HER2-negative Breast Cancer
Interventions
First Posted Date
2022-11-07
Last Posted Date
2025-07-02
Lead Sponsor
Atossa Therapeutics, Inc.
Target Recruit Count
214
Registration Number
NCT05607004
Locations
🇺🇸

California Research Institute, Los Angeles, California, United States

🇺🇸

Mayo Clinic Arizona, Phoenix, Arizona, United States

🇺🇸

University of Arizona, Tucson, Arizona, United States

and more 10 locations

Effect of Oral (Z)-Endoxifen in Premenopausal Women With Measurable Breast Density

Phase 2
Active, not recruiting
Conditions
Breast Density
Interventions
Drug: Placebo
First Posted Date
2021-10-05
Last Posted Date
2024-04-26
Lead Sponsor
Atossa Therapeutics, Inc.
Target Recruit Count
240
Registration Number
NCT05068388
Locations
🇸🇪

Karma Study Centre, Stockholm, Sweden

Topical Endoxifen in Women

Phase 2
Completed
Conditions
Mammographic Breast Density
Interventions
Drug: Placebo
Drug: Topical endoxifen
First Posted Date
2020-11-05
Last Posted Date
2021-07-12
Lead Sponsor
Atossa Therapeutics, Inc.
Target Recruit Count
90
Registration Number
NCT04616430
Locations
🇸🇪

Karolinska Institutet, Stockholm, Sodersjukhuset, Sweden

AT-301 Nasal Spray in Healthy Adults

Phase 1
Completed
Conditions
Healthy
Interventions
First Posted Date
2020-08-20
Last Posted Date
2021-01-19
Lead Sponsor
Atossa Therapeutics, Inc.
Target Recruit Count
32
Registration Number
NCT04519788
Locations
🇦🇺

CMAX Clinical Research, Adelaide, South Australia, Australia

A Pre-Surgical PK Study of IM and Intraductally Delivered Fulvestrant

Phase 2
Terminated
Conditions
Female Breast Carcinoma
Female Ductal Carcinoma In Situ
Interventions
First Posted Date
2015-09-03
Last Posted Date
2024-04-03
Lead Sponsor
Atossa Therapeutics, Inc.
Target Recruit Count
3
Registration Number
NCT02540330
Locations
🇺🇸

The Johns Hopkins School of Medicine, Baltimore, Maryland, United States

🇺🇸

Montefiore Medical Center, Bronx, New York, United States

🇺🇸

Columbia University Medical Center, New York, New York, United States

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News

Atossa's (Z)-Endoxifen Shows 77.7% Tumor Reduction in Phase 2 Breast Cancer Trial

Atossa Therapeutics' low-dose (Z)-endoxifen demonstrated significant tumor shrinkage with a 77.7% reduction in functional tumor volume in women with ER+/HER2- breast cancer during the I-SPY 2 trial.

Atossa Therapeutics Shifts Focus to Metastatic Breast Cancer with (Z)-Endoxifen, Strengthens Patent Portfolio

Atossa Therapeutics has strategically repositioned (Z)-endoxifen to target metastatic breast cancer, addressing a significant unmet medical need where current treatments offer limited durability and substantial side effects.

Atossa Therapeutics Unveils SMART 2.0 Study to Reduce Interval Breast Cancer in High-Risk Women

Atossa Therapeutics has proposed a pioneering Phase 3 clinical study called SMART 2.0 to investigate if oral (Z)-endoxifen can reduce interval breast cancer in high-risk women identified through advanced mammographic screening.

Nona Biosciences Expands Reach with Strategic Partnerships in Animal Health and Breast Cancer Therapeutics

Nona Biosciences has entered a strategic collaboration with Invetx to develop next-generation animal health biotherapeutics using their proprietary HCAb Harbour Mice® platform, marking their first expansion into the animal health sector.

Atossa Therapeutics' (Z)-Endoxifen Shows Promise in Phase 2 Breast Cancer Trial

Atossa Therapeutics presented Phase 2 EVANGELINE trial data at SABCS 2024, evaluating (Z)-endoxifen for ER+/HER2-negative breast cancer in premenopausal women.

Atossa's Endoxifen Shows Promise in Reducing Mammographic Breast Density in Phase II Trial

Novel selective estrogen receptor modulator (Z)-endoxifen demonstrates significant reduction in mammographic breast density in premenopausal women during Phase II KARISMA trial.

(Z)-Endoxifen Demonstrates Significant Reduction in Mammographic Breast Density in Phase 2 Trial

Atossa Therapeutics' Phase 2 KARISMA-Endoxifen trial shows (Z)-endoxifen significantly reduces mammographic breast density (MBD) in premenopausal women.

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