MASSACHUSETTS EYE AND EAR INFIRMARY

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1824-01-01

Employees: -

Market Cap: -

Website: http://www.masseyeandear.org/

Clinical Trials

Latanoprost Eluting Contact Lens for Treating Glaucoma and Ocular Hypertension

Phase 1

Recruiting

Conditions: Glaucoma
Ocular Hypertension

Interventions: Drug: Topical Latanoprost
Drug: Latanoprost eluting contact lens

First Posted Date: 2020-08-05

Last Posted Date: 2023-04-06

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 31

Registration Number: NCT04500574

Locations: 🇺🇸
Massachusetts Eye and Ear, Boston, Massachusetts, United States

Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy

Phase 2

Recruiting

Conditions: Fuchs Endothelial Corneal Dystrophy

Interventions: Drug: N-acetyl cysteine (NAC) 10% solution
Drug: N-acetyl cysteine (NAC) 20% solution
Drug: Visine Dry Eye Relief eye drops

First Posted Date: 2020-06-19

Last Posted Date: 2024-06-20

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 45

Registration Number: NCT04440280

Locations: 🇺🇸
Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

Feasibility Tests for Various Prism Configurations for Visual Field Loss

Not Applicable

Recruiting

Conditions: Hemianopia, Homonymous
Visual Field Defect, Peripheral
Visual Field Constriction Bilateral
Tunnel Vision
Visual Field Defect Homonymous Bilateral

Interventions: Device: High power prisms

First Posted Date: 2020-06-11

Last Posted Date: 2024-03-13

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 20

Registration Number: NCT04424979

Locations: 🇺🇸
Schepens Eye Research Institute, Boston, Massachusetts, United States

Brain-Computer Interfaces in Laryngeal Dystonia

Not Applicable

Recruiting

Conditions: Laryngeal Dystonia

Interventions: Device: neurofeedback brain-computer interface (BCI)

First Posted Date: 2020-06-09

Last Posted Date: 2024-11-21

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 40

Registration Number: NCT04421365

Locations: 🇺🇸
Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

Lenvatinib in Locally Advanced Invasive Thyroid Cancer

Phase 2

Recruiting

Conditions: Advanced Cancer
Differentiated Thyroid Cancer

Interventions: Drug: LENVATINIB

First Posted Date: 2020-03-25

Last Posted Date: 2023-11-03

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 30

Registration Number: NCT04321954

Locations: 🇺🇸
Memorial Sloan Kettering Cancer Center, New York, New York, United States
🇺🇸
Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States
🇺🇸
MD Anderson Cancer Center, Houston, Texas, United States

Anti-VEGF Therapy for Acute Thyroid Eye Disease

Phase 2

Recruiting

Conditions: Thyroid Eye Disease

Interventions: Drug: Sub-tenon injection of saline followed by a sub-tenon injection of aflibercept
Drug: Sub-tenon injection of hyaluronidase (HA) followed by a sub-tenon injection of aflibercept
Drug: Sub-tenon injection of hyaluronidase (HA) alone

First Posted Date: 2020-03-17

Last Posted Date: 2023-03-20

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 24

Registration Number: NCT04311606

Locations: 🇺🇸
Mass Eye and Ear, Boston, Massachusetts, United States

Therapeutic Contact Lens Drug Delivery System (TCL-DDS) in Patients With Recurrent Cystoid Macular Edema

Phase 1

Recruiting

Conditions: Cystoid Macular Edema

Interventions: Drug: Dexamethasone

First Posted Date: 2020-01-13

Last Posted Date: 2022-10-31

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 6

Registration Number: NCT04225611

Locations: 🇺🇸
MEEI, Boston, Massachusetts, United States

Analysis of Vestibular Compensation Following Clinical Intervention for Vestibular Schwannoma

Not Applicable

Conditions: Vestibular Schwannoma
Vestibular Disorder
Dizziness
Migraine
Vestibular Migraine
Motion Sickness

Interventions: Behavioral: Temporal Binding Adaptation - TBW training
Behavioral: Temporal Binding Adaptation - PSS adaptation with VI stimulation
Behavioral: Temporal Binding Adaptation - PSS training
Behavioral: Chronic Motion-modulated Stimulation

First Posted Date: 2019-12-12

Last Posted Date: 2023-03-16

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 472

Registration Number: NCT04196933

Locations: 🇺🇸
Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

An FMRI Investigation of the Effects of IV Lidocaine on Tinnitus

Early Phase 1

Recruiting

Conditions: Tinnitus

Interventions: Drug: IV Lidocaine

First Posted Date: 2019-12-10

Last Posted Date: 2024-11-21

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 40

Registration Number: NCT04192773

Locations: 🇺🇸
Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

Assessment of Corneal Endothelial Function Following Hypoxic Stress

Phase 1

Recruiting

Conditions: Fuchs' Endothelial Corneal Dystrophy

Interventions: Device: Wearing of contact lens

First Posted Date: 2019-11-25

Last Posted Date: 2024-06-20

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 20

Registration Number: NCT04175938

Locations: 🇺🇸
Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

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