DeepMed Research

MASSACHUSETTS EYE AND EAR INFIRMARY

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1824-01-01

Employees: -

Market Cap: -

Website: http://www.masseyeandear.org/

Clinical Trials

Lenvatinib in Locally Advanced Invasive Thyroid Cancer

Phase 2

Recruiting

Conditions: Advanced Cancer
Differentiated Thyroid Cancer

Interventions: Drug: LENVATINIB

First Posted Date: 2020-03-25

Last Posted Date: 2023-11-03

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 30

Registration Number: NCT04321954

Locations: 🇺🇸
Memorial Sloan Kettering Cancer Center, New York, New York, United States
🇺🇸
Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States
🇺🇸
MD Anderson Cancer Center, Houston, Texas, United States

Anti-VEGF Therapy for Acute Thyroid Eye Disease

Phase 2

Recruiting

Conditions: Thyroid Eye Disease

Interventions: Drug: Sub-tenon injection of hyaluronidase (HA) followed by a sub-tenon injection of aflibercept
Drug: Sub-tenon injection of hyaluronidase (HA) alone
Drug: Sub-tenon injection of saline followed by a sub-tenon injection of aflibercept

First Posted Date: 2020-03-17

Last Posted Date: 2023-03-20

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 24

Registration Number: NCT04311606

Locations: 🇺🇸
Mass Eye and Ear, Boston, Massachusetts, United States

Therapeutic Contact Lens Drug Delivery System (TCL-DDS) in Patients With Recurrent Cystoid Macular Edema

Phase 1

Recruiting

Conditions: Cystoid Macular Edema

Interventions: Drug: Dexamethasone

First Posted Date: 2020-01-13

Last Posted Date: 2022-10-31

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 6

Registration Number: NCT04225611

Locations: 🇺🇸
MEEI, Boston, Massachusetts, United States

Analysis of Vestibular Compensation Following Clinical Intervention for Vestibular Schwannoma

Not Applicable

Withdrawn

Conditions: Vestibular Schwannoma
Vestibular Disorder
Dizziness
Migraine
Vestibular Migraine
Motion Sickness

Interventions: Behavioral: Temporal Binding Adaptation - TBW training
Behavioral: Temporal Binding Adaptation - PSS adaptation with VI stimulation
Behavioral: Temporal Binding Adaptation - PSS training
Behavioral: Chronic Motion-modulated Stimulation

First Posted Date: 2019-12-12

Last Posted Date: 2025-04-16

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 472

Registration Number: NCT04196933

Locations: 🇺🇸
Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

An FMRI Investigation of the Effects of IV Lidocaine on Tinnitus

Early Phase 1

Recruiting

Conditions: Tinnitus

Interventions: Drug: IV Lidocaine

First Posted Date: 2019-12-10

Last Posted Date: 2025-03-20

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 40

Registration Number: NCT04192773

Locations: 🇺🇸
Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

Assessment of Corneal Endothelial Function Following Hypoxic Stress

Phase 1

Recruiting

Conditions: Fuchs' Endothelial Corneal Dystrophy

Interventions: Device: Wearing of contact lens

First Posted Date: 2019-11-25

Last Posted Date: 2025-05-21

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 20

Registration Number: NCT04175938

Locations: 🇺🇸
Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

FLuorometholone as Adjunctive MEdical Therapy for TT Surgery (FLAME) Trial

Phase 3

Completed

Conditions: Trachomatous Trichiasis (TT)
Trichiasis
Eye Diseases
Eyelid Diseases
Trachomatous

Interventions: Drug: Fluorometholone 0.1% Oph Susp
Drug: Artificial Tears

First Posted Date: 2019-11-04

Last Posted Date: 2025-02-27

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 2410

Registration Number: NCT04149210

Locations: 🇪🇹
Oromia Health Bureau, Addis Ababa, Ethiopia

Netarsudil Use After Descemetorhexis Without Endothelial Keratoplasty

Early Phase 1

Completed

Conditions: Fuchs' Endothelial Dystrophy
Cataract

Interventions: Drug: Netarsudil 0.02% Ophthalmic Solution

First Posted Date: 2019-08-14

Last Posted Date: 2021-01-26

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 10

Registration Number: NCT04057053

Locations: 🇺🇸
Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

Pilocarpine and Brimonidine in Patients With Monofocal Lenses

Early Phase 1

Conditions: Pseudophakia
Presbyopia

Interventions: Drug: Brimonidine, pilocarpine

First Posted Date: 2019-01-31

Last Posted Date: 2019-01-31

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 33

Registration Number: NCT03825081

Locations: 🇺🇸
Massachusetts Eye and Ear, Boston, Massachusetts, United States

Clinical Trial to Improve the Magnetic Levator Prosthesis

Not Applicable

Completed

Conditions: Myasthenia Gravis
Stroke
Ptosis, Eyelid
Blepharoptosis
Traumatic Brain Injury

Interventions: Device: Magnetic Levator Prosthesis (MLP)

First Posted Date: 2019-01-28

Last Posted Date: 2024-05-10

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 17

Registration Number: NCT03818204

Locations: 🇺🇸
Schepens Eye Research Institute, Boston, Massachusetts, United States

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