4SC AG
A Phase 1, Open-label Study of the Absorption, Metabolism, Excretion of [14C]-Resminostat
- Conditions
- Interventions
- First Posted Date
- 2021-07-08
- Last Posted Date
- 2022-02-18
- Lead Sponsor
- 4SC AG
- Target Recruit Count
- 5
- Registration Number
- NCT04955340
- Locations
- 🇬🇧
Covance Clinical research Unit Ltd., Leeds, United Kingdom
Domatinostat in Combination With Avelumab in Patients With Treatment-naïve Metastatic Merkel Cell Carcinoma (MERKLIN 1)
- Conditions
- Interventions
- First Posted Date
- 2021-05-06
- Last Posted Date
- 2021-11-18
- Lead Sponsor
- 4SC AG
- Registration Number
- NCT04874831
Domatinostat in Combination With Avelumab in Patients With Advanced Merkel Cell Carcinoma Progressing on Anti-PD-(L)1
- Conditions
- Interventions
- First Posted Date
- 2020-05-19
- Last Posted Date
- 2024-05-08
- Lead Sponsor
- 4SC AG
- Target Recruit Count
- 19
- Registration Number
- NCT04393753
- Locations
- 🇳🇱
Netherlands Cancer Institute Amsterdam, Amsterdam, Netherlands
🇮🇹Istituto Nazionale Tumori Fondazione G.Pascale, Naples, Italy
🇮🇹IOV - Istituto Oncologico Veneto IRCCS, Padova, Italy
4SC-202 in Combination With Pembrolizumab in Patients Primary Refractory/Non-responding to Prior Anti-PD-1 Therapy
- Conditions
- Interventions
- First Posted Date
- 2017-09-12
- Last Posted Date
- 2022-02-04
- Lead Sponsor
- 4SC AG
- Target Recruit Count
- 40
- Registration Number
- NCT03278665
- Locations
- 🇩🇪
Universitätsklinikum Essen, Essen, Germany
🇩🇪Universitätsklinikum Heidelberg, Heidelberg, Germany
🇩🇪Universitätsklinikum Würzburg, Würzburg, Germany
Resminostat for Maintenance Treatment of Patients With Advanced Stage Mycosis Fungoides (MF) or Sézary Syndrome (SS)
- Conditions
- Interventions
- First Posted Date
- 2016-11-02
- Last Posted Date
- 2023-09-06
- Lead Sponsor
- 4SC AG
- Target Recruit Count
- 201
- Registration Number
- NCT02953301
- Locations
- 🇯🇵
Okayama University Hospital, Okayama, Japan
🇵🇱Uniwersytecki Szpital Kliniczny im. WAM - CSW, Łódź, Poland
🇬🇷ATTIKON Hospital and Cutaneous Lymphoma Clinic, Athens, Greece
Oral Histone Deacetylase Inhibitor 4SC-202 in Patients With Advanced Hematologic Malignancies (TOPAS)
- Conditions
- First Posted Date
- 2011-04-29
- Last Posted Date
- 2015-04-01
- Lead Sponsor
- 4SC AG
- Target Recruit Count
- 36
- Registration Number
- NCT01344707
- Locations
- 🇩🇪
Universiätsklinikum Köln, Köln, Germany
🇩🇪Robert-Bosch-Krankenhaus, Stuttgart, Germany
🇩🇪Universitätsklinikum Würzburg, Würzburg, Germany
4SC-201 (Resminostat) in Advanced Colorectal Carcinoma
- Conditions
- Interventions
- First Posted Date
- 2011-01-14
- Last Posted Date
- 2015-04-01
- Lead Sponsor
- 4SC AG
- Target Recruit Count
- 17
- Registration Number
- NCT01277406
- Locations
- 🇩🇪
KTB-Klinik für Tumorbiologie, Klinik für Internistische Onkologie, Freiburg, Germany
🇩🇪University of Heidelberg, Heidelberg, Germany
🇩🇪Universitaetsklinikum Tuebingen; Med. Klinik und Poliklinik II, Tuebingen, Germany
Open Label, Dose Escalation Trial of Oral Eg5 Kinesin-spindle Inhibitor 4SC-205 in Patients With Advanced Malignancies
- Conditions
- Interventions
- First Posted Date
- 2010-02-09
- Last Posted Date
- 2015-04-13
- Lead Sponsor
- 4SC AG
- Target Recruit Count
- 60
- Registration Number
- NCT01065025
- Locations
- 🇩🇪
Universitätsklinikum Essen, Essen, Germany
🇩🇪Klinik für Tumorbiologie an der Albert-Ludwigs-Universität Freiburg (KTB), Freiburg, Germany
Single Dose Study With 4SC-203 in Healthy Volunteers
- First Posted Date
- 2010-01-22
- Last Posted Date
- 2011-01-13
- Lead Sponsor
- 4SC AG
- Target Recruit Count
- 60
- Registration Number
- NCT01054937
- Locations
- 🇩🇪
Charité Research Organisation, Berlin, Germany
Resminostat (4SC-201) in Relapsed or Refractory Hodgkin's Lymphoma
- First Posted Date
- 2009-12-23
- Last Posted Date
- 2014-01-16
- Lead Sponsor
- 4SC AG
- Target Recruit Count
- 37
- Registration Number
- NCT01037478
- Locations
- 🇨🇿
Fakultní nemocnice Kralovske Vinohrady, Praha, Czech Republic
🇵🇱Uniwersyteckie Centrum Kliniczne, Gdańsk, Poland
🇵🇱Samodzielny Publiczny Szpital Kliniczny Nr.1 w Poznaniu, Poznan, Poland