DeepMed Research

ABBVIE

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 2013-01-01

Employees: -

Market Cap: $346B

Website: http://www.abbvie.com

Clinical Trials

A Study of Glecaprevir (GLE)/Pibrentasvir (PIB) in Treatment-Naive Adults With Chronic Hepatitis C Virus (HCV) Genotype 1-6 Infection and Compensated Cirrhosis

Phase 3

Completed

Conditions: Hepatitis C Virus (HCV)

Interventions: Drug: Glecaprevir/Pibrentasvir

First Posted Date: 2017-03-24

Last Posted Date: 2020-07-13

Lead Sponsor: AbbVie

Target Recruit Count: 343

Registration Number: NCT03089944

Locations: 🇺🇸
Piedmont Hospital /ID# 162646, Atlanta, Georgia, United States
🇬🇷
General Hospital of Athens Laiko /ID# 162786, Athens, Attiki, Greece
🇬🇷
Bioclinic Thessaloniki /ID# 162785, Thessaloniki, Greece

and more 110 locations

A Study on the Safety and Tolerability of Rovalpituzumab Tesirine in Japanese Patients With Advanced, Recurrent Small Cell Lung Cancer

Phase 1

Completed

Conditions: Small Cell Lung Cancer

Interventions: Drug: Rovalpituzumab tesirine

First Posted Date: 2017-03-22

Last Posted Date: 2021-08-03

Lead Sponsor: AbbVie

Target Recruit Count: 29

Registration Number: NCT03086239

Locations: 🇯🇵
National Cancer Ctr Hosp East /ID# 161432, Kashiwa-shi, Chiba, Japan
🇯🇵
Kyushu University Hospital /ID# 161430, Fukuoka-shi, Fukuoka, Japan
🇯🇵
Kinki University -Osakasayama Campus /ID# 161431, Osakasayama-shi, Osaka, Japan

and more 2 locations

A Phase 3 Study to Compare Upadacitinib to Abatacept in Subjects With Rheumatoid Arthritis on Stable Dose of Conventional Synthetic Disease- Modifying Antirheumatic Drugs (csDMARDs) Who Have an Inadequate Response or Intolerance to Biologic DMARDs

Phase 3

Completed

Conditions: Rheumatoid Arthritis (RA)

Interventions: Drug: Placebo for abatacept (0.9% Sodium Chloride Injection or Solution for Infusion)
Drug: Abatacept
Drug: Upadacitinib
Drug: Placebo for upadacitinib

First Posted Date: 2017-03-22

Last Posted Date: 2024-07-18

Lead Sponsor: AbbVie

Target Recruit Count: 657

Registration Number: NCT03086343

Locations: 🇺🇸
SunValley Arthritis Center, Lt /ID# 154558, Peoria, Arizona, United States
🇺🇸
AZ Arthritis & Rheum Research /ID# 156539, Sun City, Arizona, United States
🇺🇸
CHI St. Vincent Medical Group /ID# 154561, Hot Springs, Arkansas, United States

and more 158 locations

A Study of the Safety and Tolerability of ABBV-621 in Participants With Previously-Treated Solid Tumors and Hematologic Malignancies

Phase 1

Completed

Conditions: Advanced Solid Tumors
Hematologic Malignancies
Cancer

Interventions: Drug: ABBV-621
Drug: FOLFIRI
Drug: Bevacizumab
Drug: Venetoclax

First Posted Date: 2017-03-17

Last Posted Date: 2022-12-09

Lead Sponsor: AbbVie

Target Recruit Count: 153

Registration Number: NCT03082209

Locations: 🇺🇸
Millennium Oncology /ID# 214981, Houston, Texas, United States
🇺🇸
Yale University /ID# 158029, New Haven, Connecticut, United States
🇺🇸
The University of Chicago Medical Center /ID# 158030, Chicago, Illinois, United States

and more 16 locations

A Study of the Safety, Tolerability and Pharmacokinetics of ABBV-368 as a Single Agent and Combination in Subjects With Locally Advanced or Metastatic Solid Tumors

Phase 1

Completed

Conditions: Advanced Solid Tumors Cancer

Interventions: Drug: ABBV-368
Drug: ABBV-181

First Posted Date: 2017-03-07

Last Posted Date: 2022-04-28

Lead Sponsor: AbbVie

Target Recruit Count: 139

Registration Number: NCT03071757

Locations: 🇫🇷
Institut Gustave Roussy /ID# 165035, Villejuif Cedex, Val-de-Marne, France
🇫🇷
AP-HM - Hopital de la Timone /ID# 165036, Marseille CEDEX 05, Bouches-du-Rhone, France
🇺🇸
Carolina BioOncology Institute /ID# 160786, Huntersville, North Carolina, United States

and more 24 locations

A Study of Venetoclax in Combination With Low Dose Cytarabine Versus Low Dose Cytarabine Alone in Treatment Naive Patients With Acute Myeloid Leukemia Who Are Ineligible for Intensive Chemotherapy

Phase 3

Active, not recruiting

Conditions: Acute Myeloid Leukemia (AML)

Interventions: Drug: Placebo
Drug: Venetoclax
Drug: Cytarabine

First Posted Date: 2017-03-03

Last Posted Date: 2025-03-21

Lead Sponsor: AbbVie

Target Recruit Count: 211

Registration Number: NCT03069352

Locations: 🇺🇸
H. Lee Moffit Cancer Center /ID# 164273, Tampa, Florida, United States
🇺🇸
Norton Cancer Institute /ID# 158998, Louisville, Kentucky, United States
🇦🇷
Cemic /Id# 159676, Buenos Aires, Argentina

and more 106 locations

A Study to Evaluate the Efficacy and Safety of Glecaprevir/Pibrentasvir in Adults With Chronic Hepatitis C Virus Genotype 1 - 6 Infection and Renal Impairment

Phase 3

Completed

Conditions: Hepatitis C Virus (HCV)

Interventions: Drug: Glecaprevir/pibrentasvir

First Posted Date: 2017-03-03

Last Posted Date: 2019-03-04

Lead Sponsor: AbbVie

Target Recruit Count: 101

Registration Number: NCT03069365

Locations: 🇺🇸
Northwest Louisiana Nephrology /ID# 160652, Shreveport, Louisiana, United States
🇩🇪
Univ Johannes Gutenberg /ID# 160828, Mainz, Germany
🇵🇷
School of Medicine University of Puerto Rico-Medical Sciences Campus /ID# 160755, San Juan, Puerto Rico

and more 35 locations

A Study to Evaluate the Pharmacokinetics, Safety, and Efficacy of Glecaprevir/Pibrentasvir in Pediatric Subjects With Genotypes 1-6 Chronic Hepatitis C Virus (HCV) Infection

Phase 2

Completed

Conditions: Hepatitis C Virus (HCV)

Interventions: Drug: Glecaprevir + Pibrentasvir Pediatric Formulation
Drug: Glecaprevir/Pibrentasvir Adult Formulation

First Posted Date: 2017-03-01

Last Posted Date: 2023-05-09

Lead Sponsor: AbbVie

Target Recruit Count: 129

Registration Number: NCT03067129

Locations: 🇺🇸
Boston Childrens Hospital /ID# 157988, Boston, Massachusetts, United States
🇺🇸
Indiana University /ID# 158001, Indianapolis, Indiana, United States
🇧🇪
UZ Leuven /ID# 162174, Leuven, Belgium

and more 35 locations

Study Comparing Rovalpituzumab Tesirine Versus Topotecan in Subjects With Advanced or Metastatic Small Cell Lung Cancer With High Levels of Delta-like Protein 3 (DLL3) and Who Have First Disease Progression During or Following Front-line Platinum-based Chemotherapy (TAHOE)

Phase 3

Completed

Conditions: Small Cell Lung Cancer

Interventions: Drug: Topotecan
Drug: Rovalpituzumab tesirine
Drug: Dexamethasone

First Posted Date: 2017-02-23

Last Posted Date: 2021-02-23

Lead Sponsor: AbbVie

Target Recruit Count: 444

Registration Number: NCT03061812

Locations: 🇺🇸
Georgia Cancer Center /ID# 160206, Atlanta, Georgia, United States
🇺🇸
Cedars-Sinai Medical Center /ID# 157102, Beverly Hills, California, United States
🇺🇸
Mitchell Cancer Institute /ID# 158151, Mobile, Alabama, United States

and more 192 locations

Real World Evidence of the Effectiveness of Paritaprevir/Ritonavir (r) - Ombitasvir, + Dasabuvir Without Ribavirin in Participants With Chronic Hepatitis C and Compensated Liver Cirrhosis in the Russian Federation

Completed

Conditions: Chronic Hepatitis C

First Posted Date: 2017-02-15

Last Posted Date: 2019-03-14

Lead Sponsor: AbbVie

Target Recruit Count: 60

Registration Number: NCT03053180

Locations: 🇷🇺
KOGBUZ Kirovsk Infect Hosp, Kirov, Russian Federation
🇷🇺
South-Ural State Med. Academy, Chelyabinsk, Russian Federation
🇷🇺
Specialized Clinical Infectiou, Krasnodar, Russian Federation

and more 4 locations

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